Cefprozil concentrations in middle ear fluid of children with acute otitis media

Pediatric Infectious Disease Journal

Volumn 19, Issue 3, 2000, Pages 268-270

  Trujillo, Monica ^a,c   Correa, Nidia ^a   Olsen, Kurt ^b   Trujillo, Hugo ^a   Realpe, Teresa ^c   Mejia, Gloria I ^a   Robledo, Jaime ^a   McCracken Jr , George H ^b  

^a Corp para Invest Biológicas ^*  (Colombia)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c NONE

Author keywords

Acute otitis media; Cefprozil; Middle ear fluid

Indexed keywords

CEFPROZIL;

ADOLESCENT; ARTICLE; CHILD; CLINICAL ARTICLE; DRUG BLOOD LEVEL; DRUG EFFICACY; HAEMOPHILUS INFLUENZAE; HUMAN; INFANT; MIDDLE EAR; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OTITIS MEDIA; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIAE;

ACUTE DISEASE; ADOLESCENT; CEPHALOSPORINS; CHILD; CHILD, PRESCHOOL; HUMANS; INFANT; MICROBIAL SENSITIVITY TESTS; OTITIS MEDIA WITH EFFUSION;

EID: 0034101034     PISSN: 08913668     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006454-200003000-00026     Document Type: Article

References (11)

1. Blumer J. Clinical perspectives on sinusitis and otitis media. Pediatr Infect Dis J 1998;17:S68-72.
2. Craig WA, Andes D. Pharmacokinetics and pharmacodynamics of antibiotics in otitis media. Pediatr Infect Dis J 1996;15:255-9.
3. Pichichero ME, Pichichero CL. Persistent acute otitis media: II. Antimicrobial treatment. Pediatr Infect Dis J 1995;14: 183-8.
4. Shyu WC, Haddad J, Reilly J, et al. Penetration of cefprozil into middle ear fluid of patients with acute otitis media. Antimicrob Agents Chemother 1994;38:2210-12.
5. Simon H, Yin T. Microbioassay of antimicrobial agents. Appl Microbiol 1970;19:573-9.
6. Saez-Llorens X, Shyu WC, Shelton S, et al. Pharmacokinetics of cefprozil in infants and children. Antimicrob Agents Chemother 1990;34:2152-5.
7. Spangler SK, Jacobs MR, Appelbaum PC. Activities of RPR 106972 (a new oral streptogramin), cefditoren (a new oral cephalosporin), two new oxazolidinones (U-100592 and U-100766), and other oral and parenteral agents against 203 penicillin-susceptible and -resistant pneumococci. Antimicrob Agents Chemother 1996;40:481-4.
8. Doern GV, Brueggemann AB, Pierce G, Holley HP Jr, Rauch A. Antibiotic resistance among clinical isolates of Haemophilus influenzae in the United States in 1994 and 1995 and detection of beta-lactamase-positive strains resistant to amoxicillin-clavulanate: results of a National Multicenter Surveillance Study. Antimicrob Agents Chemother 1997;41: 292-7.
9. Klein JO. The "in vivo sensitivity test" for acute otitis media revisited. Pediatr Infect Dis J 1998;17:774-5.
10. Dagan R, Leibovitz E, Greenberg D, Yagupsky P, Fliss DM, Leiberman A. Early eradication of pathogens from middle ear fluid during antibiotic treatment of acute otitis media is associated with improved clinical outcome. Pediatr Infect Dis J 1998;17:776-782.
11. Carlin SA, Marchant CD, Shurin PA, Johnson CE, Super DM, Rehmus JM. Host factors and early therapeutic response in acute otitis media. J Pediatr 1991;118:178-83.