Microsatellite instability analysis in tumors with different mechanisms for total loss of HLA expression

Cancer Immunology Immunotherapy

Volumn 48, Issue 12, 2000, Pages 684-690

  Jimenez, P ^a   Canton J ^a   Concha, A ^a   Cabrera, T ^a   Fernandez M ^a   Real, L M ^a   Garcia A ^a   Serrano, A ^a   Garrido, F ^a   Ruiz Cabello, F ^a  

^a HOSPITAL UNIVERSITARIO VIRGEN DE LAS NIEVES   (Spain)

Author keywords

Loss of heterozygosity; Microsatellite instability; 2 Microglobulin

Indexed keywords

BETA 2 MICROGLOBULIN; HLA ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; BASE MISPAIRING; DNA REPAIR; GENE MUTATION; HETEROZYGOSITY; HUMAN; HUMAN CELL; IMMUNOGENICITY; IMMUNOTHERAPY; MAJOR HISTOCOMPATIBILITY COMPLEX; MICROSATELLITE INSTABILITY; PHENOTYPE; PRIORITY JOURNAL; TUMOR CELL LINE;

EID: 0034100822     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002620050017     Document Type: Article

References (36)

1. Barnstable CJ, Bodmer WF, Brown G, Galfre BB, Milstein C, Williams AF, Ziegler A (1978) Production of monoclonal antibodies to group A erythrocytes HLA and other human cell surface antigens. New tools for genetic analysis. Cell 14:9
2. Benitez R, Godelaine D, Lopez Nevot M, Brasseur F, Marchand M, Cabrera T, Van Baren N, Andry G, Jimenez P, Landry C, Ruiz-Cabello F, Boon T, Garrido F (1998) Mutations of β2-microglobulin gene result in lack of HLA class I molecules on melanoma cells of two patients immunized with MAGE peptides. Tissue Antigens 52:520
3. Bicknell DC, Kaklamanis L, Hampson R, Bodmer WF, Karran P (1996) Selection for β2-microglobulin mutation in mismatch repair-defective colorectal carcinomas. Curr Biol 6:1695
4. Bicknell DC, Rowan A, Bodmer WF (1994) Beta-2 microglobulin gene mutations: A study of stablished colorectal cell lines and fresh tumors. Proc Natl Acad Sci USA 91:4751
5. Blanchet O, Bourge JF, Zinszer H, Tatari Z, Degos L, Paul P (1991) DNA binding of regulatory factors interacting with MHC-class-I gene enhancer correlates with MHC class I transcriptional level in class I defective cell lines. Int J Cancer 6:138
6. Branch P, Bicknell DC, Rowan A, Bodmer WF, Karran P (1995) Immune surveillance in colorectal carcinoma. Nat Genet 9:231
7. Browning DC, Rowan A, Bodmer W (1994) β2-Microglobulingene mutations: A study of established colorectal cell lines and fresh tumors. Proc Natl Acad Sci USA 91:4751
8. Burrone OR, Fefford RF, Gilmore D, Milstein C (1985) Stimulation of HLA ABC by viral IFN. The derivation of Molt4 variant and the differential expression of HLA ABC subset. EMBO J 4:2855
9. Chen HL, Gabrilovich D, Virmani A, Ratnani I, Girgis KR, Nadaf-Rahrov S, Fernandez-Viña M, Carbone P (1996) Structural and functional analysis of β2-microglobulin abnormalities in human lung and breast cancer. Int J Cancer 67:756
10. Cromme FV, Airley J, Heemels MT, Ploegh HL, Keating PJ, Stern PL, Meijer CJ, Walboomers JM (1994) Loss of transporter protein encoded by the TAP-1 gene is highly correlated with loss of HLA expression in cervical carcinomas. J Exp Med 179:335
11. Drew PD, Lonergan M, Goldstein ME, Lampson LA, Ozato K, Mc Farlin DE (1993) Regulation of MHC class I and β2-microglobulin gene expression in human neuronal cells. J Immunol 150:3300
12. D'Urso CM, Wang Z, Cao Y, Tatake R, Zeff RA, Ferrone S (1991) Lack of HLA class I antigen expression by cultured melanoma cells FO-1 due to a defect in B2 m gene expression. J Clin Invest 87:284
13. Foissac A, Crouau-Roy B, Faure S, Thomsen M, Cambon-Thomsen A (1997) Microsatellites in HLA region: an overview. Tissue Antigens 49:197
14. Garrido F, Cabrera T, López-Nevot MA, Ruiz-Cabello F (1995) HLA class I antigens in human tumors. Adv Cancer Res 67:155
15. Garrido F, Ruiz-Cabello F, Cabrera T, Perez-Villar JJ, Lopez-Botet MA, Duggan-Keen M, and Stern P (1997) Implications for imunosurveillance of altered HLA class I phenotypes in human tumors. Immunol Today 18:89
16. Gyapay G, Morisette J, Vignal A, Dib C, Fizames C, Millasseau P, Marc S, Bernardi G, Lathrop M, Weissenbach J (1994) The 1993-1994 Genethon human genetic maps. Nat Genet 7:246
17. Hanawalt PC, Cooper PK, Ganesa AK, Smith CA (1979) DNA repair in bacteria and mammalians cells. Anna Rev Biochem 48:783
18. Hicklin DJ, Dellaratta DV, Kishore R, Liang B, Kageshita T, Ferrone S (1997) Beta 2-microglobulin gene mutations in human melanoma cells: molecular characterization and implications for immune surveillance. Melanoma Res 7:S67-S74
19. Hoang JM, Cottu PH, Thuille B, Salmon RJ, Thomas G, Hamelin R (1997) BAT-26 an indicator of the replication error phenotype in colorectal cancer and cell lines. Cancer Res 57:300
20. Huang J, Papadopoulos N, McKinley AJ, Farrington SM, Curtis LJ, Wyllie AH, Zheng S, Willson JKV, Markowitz SS, Morin P, Kinzler KW, Vogelstein B, Dunlop MG (1996) APC mutations in colorectal tumors with mismatch repair deficiency. Proc Natl Acad Sci USA 93:9049
21. Hutter R (1987) Worldwide agreement of the staging of cancer. Arch Surg 122:1235
22. Ionov Y, Peinado MA, Malkhosyan S, Shibata D, Perucho M (1993) Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 363:558
23. Jager E, Ringhoffer M, Altmannsberger M, Arand M, Karbach J, Jager D, Oesch F, Knuth A (1997) Immunoselection in vivo: independent loss of MHC class I and melanocyte differentiation antigen expression in metastatic melanoma. Int J Cancer 71:142
24. Lehmann F, Marchand M, Hainaut P, Pouillart P, Sastre X, Ikeda H, Boon T, Coulie PG (1995) Differences in the antigens recognized by cytolytic T cells on two successive metastases of a melanoma patient are consistent with immune selection. Eur J Immunol 25:340
25. Loeb LA (1998) Cancer cells exhibit a mutator phenotype. Adv Cancer Res 72:25
26. Lopez-Nevot MA, Cabrera T, de la Higuera B, Ruiz-Cabello F, Garrido F (1986) Production and characterization of monoclonal antibodies against leukemic cells. Inmunología 5:51
27. Miller SA, Dykes DD, Polesky HF (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16:1215
28. Pérez B, Benitez R, Fernandez MA, Oliva MR, Soto JL, Serrano MA, Lopez Nevot MA, Garrido F (1999) A new B2m mutation found in a melanoma tumor cell line. Tissue Antigens 53:569
29. Ploegh HL, Orr HT, Strominger JL (1981) Major histocompatibility antigens: the human (HLA-A,-B, -C) and murine(H-2K, H-2D) class I molecules. Cell 24:287
30. Restifo NP, Esquivel F, Kawakami Y, Yewdell J, Mulé JJ, Rosenberg SA (1993) Identification of human cancers deficient in antigen processing. J Exp Med 177:265
31. Restifo NP, Marincola FM, Kawakami Y, Taubenberger J, Yannelli JR, Rosenberg S (1996) A. Loss of functional beta2-microglobulin in metastatic melanomas from five patients receiving immunotherapy. J Natl Cancer Inst 88:100
32. Rosa F, Berissi H, Weissenbach J, Maroteaux L, Fellous M, Revel M (1983) The beta-2-microglobulin mRNA in human Daudi cells has a mutated initiation codon but is still inducible by interferon. EMBO J 2:239
33. Spear BT, Korbluth J, Strominger JL, Wilson DB (1985) Evidence for a shared HLA-A intralocus determinant defined by monoclonal antibody A131. J Exp Med 162:1802
34. Vasen HFA, Mecklin JP, Meera KP, Lynch HT (1991) The international collaborative group on hereditary nonpolyposis colorectal cancer (ICG-HNPCC). Dis Colon Rectum 34:424
35. Vitale M, Rezzani R, Zauli L, Gricolato P, Cadei M, Hicklin DJ, Ferrone S (1998) HLA class I antigen transporter associated with antigen processing (TAP1 and TAP2) down-regulation in high-grade primary breast carcinomas lesions. Cancer Res 58:737
36. Wang Z, Cao Y, Albino AP, Zeff RA, Houghton A, Ferrone S (1993) Lack of HLA class I antigen expression by melanoma cells SK-MEL-33 caused by a reading frameshift in beta 2-microglobulin messenger RNA. J Clin Invest 91:684