Weekly oxaliplatin, high-dose infusional 5-fluorouracil and folinic acid as palliative third-line therapy of advanced colorectal carcinoma

Zeitschrift fur Gastroenterologie

Volumn 38, Issue 2, 2000, Pages 153-157

  Kallen, K J ^a   Hofmann, M A K ^a   Timm, A ^a   Godderz W ^b   Galle, P R ^a   Heike, M ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b BUNDESWEHRZENTRALKRANKENHAUS KOBLENZ   (Germany)

Author keywords

5 fluorouracil; Chemotherapy; Colon neoplasms; Folinic acid oxaliplatin

Indexed keywords

FLUOROURACIL; FOLINIC ACID; OXALIPLATIN;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER SURVIVAL; CLINICAL ARTICLE; COLORECTAL CARCINOMA; CONTROLLED STUDY; DRUG EFFICACY; DRUG MEGADOSE; FEMALE; GASTROINTESTINAL TOXICITY; HUMAN; MALE; METASTASIS; OUTPATIENT CARE; TUMOR GROWTH;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; COLORECTAL NEOPLASMS; DISEASE-FREE SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; FLUOROURACIL; HUMANS; INFUSIONS, INTRAVENOUS; LEUCOVORIN; MALE; MIDDLE AGED; NEOPLASM STAGING; ORGANOPLATINUM COMPOUNDS; PALLIATIVE CARE; RETROSPECTIVE STUDIES; SALVAGE THERAPY;

EID: 0034100362     PISSN: 00442771     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2000-14853     Document Type: Article

References (25)

1. Scheithauer W, Rosen H, Kornek GV. Randomised comparison of combination chemotherapy plus supportive care with supportive care alone in patients with metastatic colorectal cancer. BMJ 1993; 306: 752-5
2. Heike M, Wölfel T, Meyer zum Büschenfelde K-H, Knuth A, Dippold WG. Adjuvante und palliative Therapie kolorektaler Karzinome. Dtsch med Wochenschr 1994; 119: 778-85
3. Jäger E, Heike M, Bernhard H et al. Weekly high-dose leucovorin versus low-dose leucovorin combined with fluorouracil in advanced colorectal cancer: Results of a randomized multicenter trial. J Clin Oncol 1996; 14: 2274-9
4. Cohen AM, Minsky BD, Schilsky RL. Cancer of the colon, rectum. In: de Vita V, Hellman S, Rosenberg S (eds.). Cancer - Principles & Practice of Oncology. New York, Philadelpia, Lippincott-Raven, 1997
5. Goldberg RM. Is repeated treatment with a 5-fluorouracil-based regimen useful in colorectal cancer? Semin Oncol 1998; 25: 21-8
6. Jäger E, Klein O, Wächter B et al. Second-line treatment with high-dose 5-fluorouracil and folinic acid in advanced colorectal cancer refractory to standard-dose 5-fluorouracil treatment. Oncology 1995; 52: 470-3
7. Rougier PR, Bugat R, Douillard JY et al. Phase II study of irinotecan in the treatment of advanced colorectal cancer in chemotherapy-naive patients and patients pretreated with fluorouracil based chemotherapy. J Clin Oncol 1997; 15: 251-60
8. Mathé G, Kidani Y, Triana Kea. A phase 1 trial of trans-1-diaminocyclohexane oxalo-platinum (L-OHP). Biomed Pharmcother 1986; 25: 199-303
9. Diaz-Rubio E, Sastre J, Zaniboni A et al. Oxaliplatin as a single agent in previously untreated colorectal carcinoma patients: A phase II multicentric study. Ann Oncol 1998; 9: 105-8
10. Bleiberg H, de Gramont A. Oxaliplatin plus 5-fluorouracil: Clinical experience in patients with advanced colorectal cancer. Semin Oncol 1998; 25: 32-9
11. De Braud F, Munzone E, Nole F et al. Synergistic activity of oxaliplatin and 5-fluorouracil in patients with metastatic colorectal cancer with progressive disease while on or after 5-fluorouracil. Am J Clin Oncol 1998; 21: 279-3
12. Raymond E, Chaney SG, Taamma A, Cvitkovic E. Oxaliplatin: A review of preclinical and clinical studies. Ann Oncol 1998; 9: 1053-71
13. Buechele T, Schoeber C, Kroening H et al. Weekly high dose 5-fluorouracil (5-FU) and folinic acid (FA) with addition of oxaliplatin after documented progression under high-dose infusional 5-FU/FA in patients with advanced colorectal cancer. Proc Am Soc Clin Oncol USA 1998; 17: 287 (abstract)
14. O'Connell MJ, Maillard JA, Kahn MJ et al. Controlled trial of fluorouracil and low-dose leucovorin given for six months as postoperative adjuvant therapy for colon cancer. J Clin Oncol 1997; 15: 246-50
15. Ardalan B, Chua L, Tian EM et al. A phase II study of weekly 24-hour infusion with high-dose fluorouracil with leucovorin in colorectal carcinoma. J Clin Oncol 1991; 9: 625-30
16. Gerard B, Bleiberg H, Van Daele D et al. Oxaliplatin combined to 5-fluorouracil and folinic acid: An effective therapy in patients with advanced colorectal cancer. Anticancer Drugs 1998; 9: 301-8
17. Aaronson NK, Ahmedzai S, Bergman B et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 1993; 85: 365-76
18. De Gramont A, Gastiaburu J, Tournigand Cea. Oxaliplatin with high-dose folinic acid and 5-fluorouracil 48 hour infusion in pretreated metastatic colorectal cancer. Proc Am Soc Clin Oncol USA 1994; 13: 220 (abstract)
19. André T, Louvet C, Tournigand C, de Gramont A. Bimonthly high-dose leucovorin, 5-fluorouracil infusion and oxaliplatin (FOLFOX3) for metastatic colorectal cancer resistant to the same leucovorin and 5-fluorouracil regimen. Ann Oncol 1998; 9: 1251-3
20. De Gramont A, Vignoud J, Tournigand C et al. Oxaliplatin with high-dose leucovorin and 5-fluorouracil 48-hour continuous infusion in pretreated metastatic colorectal cancer. Eur J Cancer 1997; 33: 214-9
21. Brienza S, Lévi F, Valori VM et al. Intensified (every 2 weeks) chronotherapy with 5-fluorouracil (5-FU), folinic acid (FA) and oxaliplatin (L-OHP) in previously treated patients with metastatic colorectal cancer. Proc Am Soc Clin Oncol USA 1993; 12: 197 (abstract)
22. Bertheault-Cvitkovic F, Jami A, Ithzaki M et al. Bi-weekly intensified ambulatory chronomodulated chemotherapy with oxaliplatin, fluorouracil and leucovorin in patients with metastatic colorectal cancer. J Clin Oncol 1996; 14: 2950-8
23. Lévi F, Zidani R, Misset JL. Randomised multicentre trial of chronotherapy with oxaliplatin, fluorouracil, and folinic acid in metastatic colorectal cancer. International Organization for Cancer Chronotherapy. Lancet 1997; 350: 681-6
24. Garufi C, Brienza S, Bensmaine MAea. Addition of oxaliplatin (L-OHP) to chronomodulated (CM), 5-fluorouracil (5-FU) and folinic acid (FA) for reversal of acquired chemoresistance in patients with advanced colorectal cancer. Proc Am Soc Clin Oncol USA 1995; 14: 192 (abstract)
25. Misset J-L. Oxaliplatin in practice. Br J Cancer 1998; 77 (suppl 4): 4-7