The 460Trp polymorphism of the human α-adducin gene is not associated with isolated systolic hypertension in elderly Australian Caucasians

Journal of Human Hypertension

Volumn 14, Issue 3, 2000, Pages 199-203

  Alam, Shahin ^a   Liyou, N ^a   Davis, D ^a   Tresillian, M ^a   Johnson, A G ^a  

^a PRINCESS ALEXANDRA HOSPITAL   (Australia)

Author keywords

Blood pressure; Genotypes; Isolated systolic hypertension; Adducin

Indexed keywords

ADDUCIN;

AGED; ARTICLE; AUSTRALIA; CAUCASIAN; CONTROLLED STUDY; FEMALE; GENE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; SYSTOLIC HYPERTENSION;

EID: 0034099902     PISSN: 09509240     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jhh.1000944     Document Type: Article

References (32)

1. Kato N et al. Lack of association between the alpha-adducin locus and essential hypertension in the Japanese population. Hypertension 1998; 31: 730-733.
2. Ward R. Familial aggregation and genetic epidemiology of blood pressure. In: Laragh JH, Brenner BM (eds). Hypertension: Pathophysiology, Diagnosis and Management. Raven Press: New York, 1995, pp 67-88.
3. Tripodi G et al. Hypertension associated point mutations in the adducin alpha and beta subunits affect actin cytoskeleton and ion transport. J Clin Invest 1996; 97: 2815-2822.
4. Castellano M et al. Alpha-adducin gene polymorphism and cardiovascular phenotypes in a general population. J Hypertens 1997; 15 (12 Pt 2): 1707-1710.
5. Cusi D et al. Polymorphisms of α-adducin and salt sensitivity in patients with essential hypertension. Lancet 1997; 349: 1353-1357.
6. Bianchi G et al. Two point mutations within the adducin genes are involved in blood pressure variation. Proc Natl Acad Sci 1994; 91: 3999-4003.
7. Bianchi G, Cusi D. The alpha-adducin polymorphism: a paradigm to analyse the genetics of primary hypertension [editorial]. Nephrol Dial Transplant 1995; 10: 763-766.
8. Manunta P, Barlassina C, Bianchi G. Adducin in essential hypertension. FEBS Lett 1998; 430: 41-44.
9. Barlassina G et al. Genetics of renal mechanisms of primary hypertension: the role of adducin. J Hypertens 1997; 15 (12 Pt 2): 1567-1571.
10. Manunta P et al. Renal genetic: mechanisms of essential hypertension. J Nephrol 1997; 10: 172-178.
11. Bianchi G et al. Genetic aspects of ion transport systems in hypertension. J Hypertens 1990; 8: S213-S218.
12. Ishikawa K et al. No association between alpha-adducin 460 polymorphism and essential hypertension in a Japanese population. Am J Hypertens 1998; 11 (4 Pt 1): 502-506.
13. Kamitani A et al. Human α-adducin gene, blood pressure, and sodium metabolism. Hypertension 1998; 32: 138-143.
14. Howes LG, Reid C, Bendle R, Weaving J. The prevalence of isolated systolic hypertension in patients 60 years of age and over attending Australian general practitioners. Blood Pressure 1998; 7: 131-132.
15. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988; 16: 1215.
16. The Systolic Hypertension in the Elderly Program SHEP) Cooperative Research Group. Rationale and design of a randomized clinical trial on prevention of stroke in Isolated Systolic Hypertension. J Clin Epidemiol 1988; 41: 1197-1208.
17. Hypertension Detection and Follow-up Program Cooperative Group. Five years findings of the hypertension detection and follow-up program: reduction in mortality of persons with high blood pressure, including mild hypertension. JAMA 1979; 242: 2562-2571.
18. Hypertension Detection and Follow-up Program Cooperative Group. Five years findings of the hypertension detection and follow-up program. Mortality by race sex and age. JAMA 1979; 242: 2572-2576.
19. Probstfield JI, Furberg CD. Systolic hypertension in the elderly: controlled or uncontrolled. Cardiovasc Clin 1990; 20: 65-84.
20. Conway J, Coats A, Value of ambulatory blood pressure monitoring in clinical pharmacology. J Hypertens 1989; 7 (Suppl 3): S29-S32.
21. Mansoor GA, McCabe EJ, White WB Long-term reproducibility of ambulatory blood pressure. J Hypertens 1994; 12: 703-708.
22. Parati G, Pomidossi G, Casadei R, Mancia G. Lack of altering reactions to intermittent cuff inflations during non-invasive blood pressure monitoring. Hypertension 1985; 7: 597-601.
23. Trazzi S et al. Reproducibility of non-invasive and intra-arterial blood pressure monitoring: implications for studies on antihypertensive treatment. J Hypertens 1991; 9: 115-119.
24. Mancia G et al. Effects of blood pressure measurement by the doctor on patient's blood pressure and heart rate. Lancet 1983; 2: 695-698.
25. Coats AJS et al. The influence of ambulatory blood pressure monitoring on the design and interpretation of trials in hypertension. J Hypertens 1992; 10: 385-391.
26. Padfield PL, Benediktsson R. Ambulatory blood pressure monitoring: from research to clinical practice. J Hum Hypertens 1995; 9: 413-416.
27. Dobson AJ. Calculating sample size. Transaction of the Menzies Foundation 1984; 7: 75-79.
28. Valdes AM, Thomson G. Detecting disease predisposing variants: the haplotype method. Am J Hum Genet 1997; 60: 703-716.
29. Jeunemaitre X et al. Haplotypes of angiotensinogen in essential hypertension. Am J Hum Genet 1997; 60: 1448-1460.
30. Spielman RS, Ewens WJ. The TDT and other family-based tests for linkage Disequilibrium and association. Am J Hum Genet 1996; 59: 983-989.
31. Harrap SB. An appraisal of the genetic approaches to hypertension. J Hypertens 1996; 14 (Suppl 5): S111-S115.
32. Smith PK et al. The 100-year conflict: salt intake and cardiovascular disease. Med J Aust 1999; 170: 174-180.