In vivo glucose detection by homonuclear spectral editing

Magnetic Resonance in Medicine

Volumn 43, Issue 5, 2000, Pages 621-626

  De Graaf, R A ^a,b   Dijkhuizen, R M ^b,c   Biessels, G J ^b   Braun, K P J ^b   Nicolay, K ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Glucose; Proton NMR spectroscopy; Rat brain; Spectral editing

Indexed keywords

NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; QUANTUM THEORY; RATS;

COHERENCE TRANSFER; FREQUENCY-SELECTIVE; MAGNETIC FIELD GRADIENT; MULTIPLE-QUANTUM COHERENCES; PROTON NMR SPECTROSCOPY; RAT BRAIN; SIGNAL SUPPRESSION; SPECTRAL EDITING;

GLUCOSE;

ANIMAL TISSUE; ARTICLE; DIABETES MELLITUS; DIAGNOSTIC IMAGING; GLUCOSE BRAIN LEVEL; GLUCOSE INFUSION; GLUCOSE METABOLISM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; RADIOFREQUENCY; RAT; SIGNAL TRANSDUCTION; THEORY;

EID: 0034099818     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1522-2594(200005)43:5<621::AID-MRM1>3.0.CO;2-3     Document Type: Article

References (25)

1. Siesjo BK. Brain energy metabolism. New York: Wiley; 1978.
2. Gyngell ML, Michaelis T, Horstermann D, Bruhn H, Hanicke W, Merboldt KD, Frahm J. Cerebral glucose is detectable by localized proton NMR spectroscopy in normal rat brain in vivo. Magn Reson Med 1991;19:489-495.
3. Merboldt KD, Bruhn H, Hanicke W, Michaelis T, Frahm J. Decrease of glucose in the human visual cortex during photic simulation. Magn Reson Med 1992;25:187-194.
4. 1H NMR difference spectra of the human brain. Magn Reson Med 1992;27:183-188.
5. 1H NMR spectra of the human brain at 4 Tesla, Magn Reson Med 1996;36:1-6.
6. Gruetter R, Ugurbil K, Seaquist ER. Steady-state cerebral glucose concentration and transport in the human brain. J Neurochem 1998;70: 397-408.
7. 1H NMR: a new tool for studying in situ brain metabolism in the living animal. FEBS Lett 1990;264:198-202.
8. 1H NMR spectroscopy. Magn Reson Med 1992;27:356-361.
9. Keltner JR, Wald LL, Ledden PJ, Chen Y-CI, Matthews RT, Kuestermann EHGK, Baker JR, Rosen BR, Jenkins BG. A localized double-quantum filter for the in vivo detection of brain glucose. Magn Reson Med 1998;39:651-656.
10. He Q, Shungu DC, van Zijl PCM, Bhujwalla ZM, Glickson JD. Single-scan in vivo lactate editing with complete lipid and water suppression by selective multiple-quantum-coherence transfer with application to tumors. J Magn Reson B 1995;106:203-211.
11. Ruiz-Cabello J, Vuister GW, Moonen CTW, van Gelderen P, Cohen JS, van Zijl PCM. Gradient-enhanced heteronuclear correlation spectroscopy. Theory and experimental aspects. J Magn Reson 1992;100:282-302.
12. Garwood M, Ke Y. Symmetric pulses to induce arbitrary flip angles with compensation for RF inhomogeneity and resonance offsets. J Magn Reson 1991;94:511-525.
13. de Graaf RA, Luo Y, Terpstra M, Merkle H, Garwood M. A new localization technique using an adiabatic pulse, BIR-4. J Magn Reson B 1995;106:245-252.
14. Sørensen OW, Eich GW, Levitt MH, Bodenhausen G, Ernst RR. Product operator formalism for the description of NMR pulse experiments. Prog NMR Spectrosc 1983;16:163-192.
15. 3He. Phys Rev B 1979;19:5666-5688.
16. McCoy M, Warren WS. Three-quantum nuclear magnetic resonance spectroscopy of liquid water: intermolecular mulitple quantum coherence generated by spin-cavity coupling. J Chem Phys 1990;93:858.
17. Warren WS, Richter W, Andreotti AH, Farmer BT II. Generation of impossible crosspeaks between bulk water and biomolecules in solution NMR. Science 1993;262:2005-2009.
18. Mori S, Hurd RE, van Zijl PCM. Imaging of shifted stimulated echoes and multiple spin echoes. Magn Reson Med 1997;37:336-340.
19. Trimble LA, Shen JF, Wilman AH, Allen PS. Lactate editing by means of selective-pulse filtering of both zero and double quantum coherence signals. J Magn Reson 1990;86:191-198.
20. de Graaf RA, Luo Y, Terpstra M, Garwood M. Spectral editing with adiabatic pulses. J Magn Reson B 1995;109:184-193.
21. de Graaf RA, Dijkhuizen RM, Tamminga KS, Nicolay K. Glucose detection by homonuclear spectral editing. In: Proceedings of the 4th Annual Meeting of ISMRM, New York, 1996. p 381.
22. de Graaf RA. Adiabatic RF pulses in in vivo NMR spectroscopy. Thesis, Utrecht University, 1998.
23. Patlak CS, Pettigrew KD. A method to obtain infusion schedules for prescribed blood concentration time courses. J Appl Physiol 1976;40: 458-463.
24. de Graaf RA. In vivo NMR spectroscopy. Principles and techniques. Chichester, UK: John Wiley & Sons; 1998.
25. Mans AM, DeJoseph MR, Davis DW, Hawkins RA. Brain energy metabolism in streptozotocin diabetes. Biochem J 1988;249:57-62.