Oxygen induction of epithelial Na+ transport requires home proteins

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 278, Issue 2 22-2, 2000, Pages

  Rafii, Bijan ^a   Coutinho, Chris ^a   Otulakowski, Gail ^a   O'Brodovich, Hugh ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Alveolar epithelium; Epithelial sodium channel

Indexed keywords

AMILORIDE; CARBON MONOXIDE; COBALT CHLORIDE; DEFEROXAMINE; HEMOPROTEIN; IRON; MESSENGER RNA; NICKEL CHLORIDE; OXYGEN; SODIUM CHANNEL;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; FETUS LUNG; HEME SYNTHESIS; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM; LUNG EDEMA; MONOLAYER CULTURE; NONHUMAN; OXYGEN CONCENTRATION; PRIORITY JOURNAL; RAT; SODIUM CURRENT; SODIUM TRANSPORT;

EID: 0034099005     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2000.278.2.l399     Document Type: Article

References (31)

1. Acker, H. Mechanisms and meaning of cellular oxygen sensing in the organism. Respir. Physiol. 95: 1-10, 1994.
2. Barker, P. M., R. C. Boucher, and J. R. Yankaskas. Bioelectric properties of cultured monolayers from epithelium of distal human fetal lung. Am. J. Physiol. Lung Cell. Mol. Physiol. 268: L270-L277, 1995.
3. Barker, P. M., M. S. Nguyen, J. T. Gatzy, B. R. Grubb, H. Norman, E. Hummler, B. Rossier, R. C. Boucher, and B. Koller. Role of γENaC subunit in lung liquid clearance and electrolyte balance in newborn mice. J. Clin. Invest. 102: 1634-1640, 1998.
4. Brown, M. J., R. E. Olver, C. A. Ramsden, L. B. Strang, and D. V. Walters. Effects of adrenaline and of spontaneous labour on the secretion and absorption of lung liquid in the fetal lamb. J. Physiol. (Lond.) 344: 137-152, 1983.
5. Canessa, C. M., J. D. Horisberger, and B. C. Rossier. Epithelial sodium channel related to proteins involved in neurodegeneration. Nature 361: 467-470, 1993.
6. + channel is made of three homologous subunits. Nature 367: 463-467, 1994.
7. + channel evaluated using sucrose gradient sedimentation analysis. J. Biol. Chem. 273: 22693-22700, 1998.
8. Fandrey, J., F. P. Seydel, C. P. Siegers, and W. Jelkmann. Role of cytochrome P450 in the control of the production of erythropoietin. Life Sci. 47: 127-134, 1990.
9. Firsov, D., I. Gautschi, A. M. Merillat, B. C. Rossier, and L. Schild. The heterotetrameric architecture of the epithelial sodium channel (ENaC). EMBO J. 17: 344-352, 1998.
10. Gilles-Gonzalez, M. A., G. S. Ditta, and D. R. Helinski. A haemoprotein with kinase activity encoded by oxygen sensor of Rhizobium meliloti. Nature 350: 170-172, 1991.
11. Goldberg, M. A., S. P. Dunning, and H. F. Bunn. Regulation of the erythropoietin gene: evidence that the oxygen sensor is a heme protein. Science 242: 1412-1415, 1988.
12. Goldberg, M. A., and T. J. Schneider. Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin. J. Biol. Chem. 269: 4355-4359, 1994.
13. Gorlach, A., G. Holtermann, W. Jelkmann, J. T. Hancock, S. A. Jones, O. T. Jones, and H. Acker. Photometric characteristics of haem proteins in erythropoietin-producing hepatoma cells (HepG2). Biochem. J. 290: 771-776, 1993.
14. Hummler, E., P. M. Barker, J. T. Gatzy, F. Beermann, C. Verdumo, A. Schmidt, R. Boucher, and B. C. Rossier. Early death due to defective neonatal lung liquid clearance in αENaC-deficient mice. Nat. Genet. 12: 325-328, 1996.
15. Jiang, C., and G. G. Haddad. A direct mechanism for sensing low oxygen levels by central neurons. Proc. Natl. Acad. Sci. USA 91: 7198-7201, 1994.
16. Lingueglia, E., N. Voilley, R. Waldmann, M. Lazdunski, and P. Barbry. Expression cloning of an epithelial amiloride-sensitive Na+ channel: a new channel type with homologies to Caenorhabditis elegans degenerins. FEBS Lett. 318: 95-99, 1993.
17. Mairbaurl, H., R. Wodopia, S. Eckes, S. Schulz, and P. Bartsch. Impairment of cation transport in A549 cells and rat alveolar epithelial cells by hypoxia. Am. J. Physiol. Lung Cell. Mol. Physiol. 273: L797-L806, 1997.
18. + channel in mice: hyperkalemia and neonatal death associated with a pseudohypoaldosteronism phenotype. Proc. Natl. Acad. Sci. USA 96: 1727-1731, 1999.
19. O'Brodovich, H., B. Rafii, and M. Post. Bioelectric properties of fetal alveolar epithelial monolayers. Am. J. Physiol. Lung Cell. Mol. Physiol. 258: L201-L206, 1990.
20. 2 alters the bioelectric properties of fetal distal lung epithelium. Am. J. Physiol. Lung Cell. Mol. Physiol. 270: L1060-L1066, 1996.
21. Planes, C., B. Escoubet, M. Blot-Chabaud, G. Friedlander, N. Farman, and C. Clerici. Hypoxia downregulates expression and activity of epithelial sodium channels in rat alveolar epithelial cells. Am. J. Respir. Cell Mol. Biol. 17: 508-518, 1997.
22. Pradervand, S., P. M. Barker, Q. Wang, S. A. Ernst, F. Beermann, B. R. Grubb, M. Burnier, A. Schmidt, R. J. M. Bindels, J. T. Gatzy, B. C. Rossier, and E. Hummler. Salt restriction induces pseudohypoaldosteronism type 1 in mice expressing low levels of the β-subunit of the amiloride-sensitive epithelial sodium channel. Proc. Natl. Acad. Sci. USA 96: 1732-1737, 1999.
23. 2-induced ENaC expression is associated with NF-κB activation and blocked by superoxide scavenger. Am. J. Physiol. Lung Cell. Mol. Physiol. 275: L764-L770, 1998.
24. Schoenfeld, N., Y. Greenblat, O. Epstein, and A. Atsmon. The effects of succinylacetone (4,6-dioxoheptanoic acid) on delta-aminolevulinate synthase activity and the content of heme in monolayers of chick embryo liver cells. Biochim. Biophys. Acta 721: 408-417, 1982.
25. Semenza, G. L., and G. L. Wang. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol. Cell. Biol. 12: 5447-5454, 1992.
26. Shibayama, N., H. Morimoto, and G. Miyazaki. Oxygen equilibrium study and light absorption spectra of Ni(II)-Fe(II) hybrid hemoglobins. J. Mol. Biol. 192: 323-329, 1986.
27. Sinclair, P., A. H. Gibbs, J. F. Sinclair, and F. de Matteis. Formation of cobalt protoporphyrin in the liver of rats. A mechanism for the inhibition of liver haem biosynthesis by inorganic cobalt. Biochem. J. 178: 529-538, 1979.
28. Taylor, C. T., S. J. Lisco, C. S. Awtrey, and S. P. Colgan. Hypoxia inhibits cyclic nucleotide-stimulated epithelial ion transport: role of nucleotide cyclases as oxygen sensors. J. Pharmacol. Exp. Ther. 284: 568-575, 1998.
29. Tschudy, D. P., R. A. Hess, and B. C. Frykholm. Inhibition of δ-aminolevulinic acid dehydrase by 4,6-dioxoheptanoic acid. J. Biol. Chem. 256: 9915-9923, 1981.
30. Yonetani, T., H. Yamamoto, and G. V. Woodrow III. Studies on cobalt myoglobins and hemoglobins. I. Preparation and optical properties of myoglobins and hemoglobins containing cobalt proto-, meso-, and deutroporphyrins and thermodynamic characterization of their reversible oxygenation. J. Biol. Chem. 249: 682-690, 1974.
31. Youngson, C., C. Nurse, H. Yeger, and E. Cutz. Oxygen sensing in airway chemoreceptors. Nature 365: 153-155, 1993.