Substrate preference profiles of proteases released by allergenic pollens

Clinical and Experimental Allergy

Volumn 30, Issue 4, 2000, Pages 571-576

  Widmer, F ^a   Hayes, P J ^a   Whittaker, R G ^a   Kumar, R K ^b  

^a CSIRO   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Airway epithelium; Allergic rhinitis; Asthma; Pollens; Proteases

Indexed keywords

AMINO ACID; ARGININE; CYSTEINE; LEUCINE; LYSINE; METHIONINE; POLLEN ANTIGEN; RAGWEED ANTIGEN; SERINE PROTEINASE;

ALLERGIC ASTHMA; ALLERGIC RHINITIS; ARTICLE; ENZYME ACTIVITY; ENZYME PURIFICATION; ENZYME SUBSTRATE COMPLEX; GRASS POLLEN; INFLAMMATION; POLLEN ALLERGY; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM;

ALLERGENS; ENDOPEPTIDASES; HUMANS; HYPERSENSITIVITY; POLLEN; SPECIES SPECIFICITY; SUBSTRATE SPECIFICITY;

EID: 0034098619     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2222.2000.00784.x     Document Type: Article

References (23)

1. 1 Peat JK, Toelle BG, Demand J, van den Berg R, Britton WJ, Woolcock AJ. Serum IgE levels, atopy, and asthma in young adults: results from a longitudinal cohort study. Allergy 1996; 51:804-10.
2. 2 Levenson T, Greenberger PA. Pathophysiology and therapy for allergic and nonallergic rhinitis: an updated review. Allergy Asthma Proc 1997; 18:213-20.
3. 3 Leung RC, Carlin JB, Burdon JG, Czarny D. Asthma, allergy and atopy in Asian immigrants in Melbourne. Med J Aust 1994; 161:418-25.
4. 4 Holt PG, Britten D, Sedgwick JD. Suppression of IgE responses by antigen inhalation: studies on the role of genetic and environmental factors. Immunology 1987; 60:97-102.
5. 5 Holt PG. Regulation of antigen-presenting cell function(s) in lung and airway tissues. Eur Respir J 1993; 6:120-9.
6. 6 Chua KY, Stewart GA, Thomas WR et al. Sequence analysis of cDNA coding for a major house dust mite allergen, Der pI: homology with cysteine proteinases. J Exp Med 1988; 167:175-82.
7. 7 Robinson C, Kalsheker NA, Srinivasan N et al. On the potential significance of the enzymatic activity of mite allergens to immunogenicity. Clues to structure and function revealed by molecular characterization. Clin Exp Allergy 1997; 27:10-21.
8. 8 Arruda LK, Vailes LD, Mann BJ et al. Molecular cloning of a major cockroach (Blattella germanica) allergen, Bla g 2: sequence homology to the aspartic proteases. J Biol Chem 1995; 270:19563-8.
9. 9 Herbert CA, King CM, Ring PC et al. Augmentation of permeability in the bronchial epithelium by the house dust mite allergen Der p1. Am J Respir Cell Mol Biol 1995; 12:369-78.
10. 10 Azghani AO. Pseudomonas aeruginosa and epithelial permeability: role of virulence factors elastase and exotoxin A. Am J Respir Cell Mol Biol 1996; 15:132-40.
11. 11 Knox B, Suphioglu C. Environmental and molecular biology of pollens. Trends Plant Sci 1996; 1:156-64.
12. 12 Knox RB, Heslop-Harrison J. Pollen wall proteins: localization and enzymic activity. J Cell Sci 1970; 6:1-27.
13. 13 Hassim Z, Maronese SE, Kumar RK. Injury to murine airway epithelial cells by pollen enzymes. Thorax 1998; 53:368-71.
14. 14 Matheson N, Schmidt J, Travis J. Isolation and properties of an angiotensin II-cleaving peptidase from mesquite pollen. Am J Respir Cell Mol Biol 1995; 12:441-8.
15. 15 Bagarozzi DA, Pike R, Potempa J, Travis J. Purification and characterization of a novel endopeptidase in ragweed (Ambrosia artemisiifolia) pollen. J Biol Chem 1996; 271:26227-32.
16. 16 Bagarozzi DA, Potempa J, Travis J. Purification and characterization of an arginine-specific peptidase from ragweed (Ambrosia artemisiifolia) pollen. Am J Respir Cell Mol Biol 1998; 18:363-9.
17. 17 Whittaker RG, Manthey MK, Le Brocque DS, Hayes PJ. A microtiter plate assay for the characterization of serine proteases by their esterase activity. Anal Biochem 1994; 220:238-43.
18. 18 Schon I, Hermann P. Thermitase as a reagent for the C-terminal peptide ester deprotection: suppression of its peptidase activity. In: Penke B, Torok A, eds. Peptides: chemistry, biology, interaction with proteins. Berlin: Walter de Gruyter, 1988:79-82.
19. 19 Baraniuk JN, Bolick M, Esch R, Buckley CE III. Quantification of pollen solute release using pollen grain column chromatography. Allergy 1992; 47:411-7.
20. 20 Baraniuk JN, Esch RE, Buckley CE. Pollen grain column chromatography: quantitation and biochemical analysis of ragweed pollen solutes. J Allergy Clin Immunol 1988; 81:1126-34.
21. 21 Maruo K, Akaike T, Matsumura Y et al. Triggering of the vascular permeability reaction by activation of the Hageman factor - prekallikrein system by house dust mite proteinase. Biochim Biophys Acta 1991; 1074:62-8.
22. 22 Suphioglu C, Singh MB, Taylor P et al. Mechanism of grass pollen-induced asthma. Lancet 1992; 339:569-72.
23. 23 Robinson MK, Babcock LS, Horn PA, Kawabata TT. Specific antibody responses to subtilisin Carlsberg (alcalase) in mice: development of an intranasal exposure model. Fundam Appl Toxicol 1996; 34:15-24.