Paraquat-induced membrane dysfunction in pulmonary microvascular endothelial cells

Pharmacology and Toxicology

Volumn 86, Issue 3, 2000, Pages 102-109

  Tsukamoto, Maki ^a   Tampo, Yoshiko ^a   Sawada, Minoru ^a   Yonaha, Masanori ^a  

^a HOKKAIDO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2,2' BIPYRIDINE; ACID PHOSPHATASE; ALPHA TOCOPHEROL; CATALASE; CHELATING AGENT; DEFEROXAMINE MESYLATE; DIMETHYLTHIOUREA; FREE RADICAL; LACTATE DEHYDROGENASE; PARAQUAT; PENTETIC ACID; PROBUCOL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SCAVENGER; SUPEROXIDE DISMUTASE; THIOUREA; TROLOX C;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ASSAY; LIPID PEROXIDATION; LUNG BLOOD VESSEL; LUNG INJURY; LUNG TOXICITY; MICROVASCULATURE; NONHUMAN; PRIORITY JOURNAL; SWINE;

ANIMALIA; SUS SCROFA;

EID: 0034097757     PISSN: 09019928     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0773.2000.pto860302.x     Document Type: Article

References (42)

1. Aruoma, O. I., P. J. Evans, H. Kaur, L. Sutcliffe & B. Halliwell: An evaluation of the antioxidant and potential pro-oxidant properties of food additives and of trolox C, vitamin E and probucol. Free Radic. Res. Commun. 1990, 10, 143-157.
2. Beckman, J. S., T. W. Beckman, J. Chen, P. A. Marshall & B. A. Freeman: Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc. Natl. Acad. Sci. USA 1990, 87, 1620-1624.
3. Becquet, F., O. Goureau, G. Soubrane, G. Coscas, Y. Courtois & D. Hicks: Superoxide inhibits proliferation and phagocytic internalization of photoreceptor outer segments by bovine retinal pigment epithelium in vitro. Exp. Cell Res. 1994, 212, 374-382.
4. Berisha, H. I., H. Pakbaz, A. Absood & S. I. Said: Nitric oxide as a mediator of oxidant lung injury due to paraquat. Proc. Natl. Acad. Sci. USA 1994, 91, 7445-7449.
5. Berridge, M. V. & A. S. Tan: Characterization of the cellular reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT): subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction. Arch. Biochem. Biophys. 1993, 303, 474-482.
6. Bus, J. S., S. D. Aust & J. E. Gibson: Superoxide- and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicity. Biochem. Biophys. Res. Commun. 1974, 58, 749-755.
7. Bus, J. S. & J. E. Gibson: Paraquat: model for oxidant-initiated toxicity. Env. Health Perspect. 1984, 55, 37-46.
8. Connolly, D. T., M. B. Knight, N. K. Harakas, A. J. Wittwer & J. Feder: Determination of the number of endothelial cells in culture using an acid phosphatase. Anal. Biochem. 1986, 152, 136-140.
9. Darley-Usmar, V. M., A. Hersey & L. G. Garland: A method for the comparative assessment of antioxidants as peroxyl radical scavengers. Biochem. Pharmacol. 1989, 38, 1465-1469.
10. Dearden, L. C., R. D. Fairshter, J. T. Morrison, A. F. Wilson & M. Brundage: Ultrastructural evidence of pulmonary capillary endothelial damage from paraquat. Toxicology 1982, 24, 211-222.
11. Forni, L. G.: Free radical reactions involving fatty acid: the pulse radiolysis approach. In: Membrane lipid oxidation. Ed.: V.-P. Carmen. CRC Press, Boca Raton, Florida, USA, 1990, vol I, pp. 15-32.
12. +, and analogs. Evidence against a "redox cycling" mechanism in MPTP neurotoxicity. Biochem. Biophys. Res. Commun. 1987, 147, 1095-1104.
13. Hara, S., T. Endo, F. Kuriiwa & S. Kano: Different effects of paraquat on microsomal lipid peroxidation in mouse brain, lung and liver. Pharmacology & Toxicology 1991, 68, 260-265.
14. Hiramatsu, M., J. Liu, R. Edamatsu, S. Ohba, D. Kadowaki & A. Mori: Probucol scavenged 1,1-diphenyl-2-picrylhydrazyl radicals and inhibited formation of thiobarbituric acid reactive substances. Free Radic. Biol. Med. 1994, 16, 201-206.
15. Hoe, S., D. A. Rowley & B. Halliwell: Reactions of ferrioxamine and desferrioxamine with the hydroxyl radical. Chem.-Biol. Interact. 1982, 41, 75-81.
16. Ishiyama, M., H. Tominaga, M. Shiga, K. Sasamoto, Y. Ohkura, K. Ueno & M. Watanabe: Novel cell proliferation and cytotoxicity assays using a tetrazolium salt that produces a water-soluble formazan dye. In Vitro Toxicology 1995, 8, 187-190.
17. Keeling, P. L. & L. L. Smith: Relevance of NADPH depletion and mixed disulphide formation in rat lung to the mechanism of cell damage following paraquat administration. Biochem. Pharmacol. 1982, 31, 3243-3249.
18. Kelner, M. J., R. Bagnell, B. Hale & N. M. Alexander: Methylene blue competes with paraquat for reduction by flavo-enzymes resulting in decreased superoxide production in the presence of heme proteins. Arch. Biochem. Biophys. 1988, 262, 422-426.
19. Kitazawa, Y., M. Matsubara, N. Takeyama & T. Tanaka: The role of xanthine oxidase in paraquat intoxication. Arch. Biochem. Biophys. 1991, 288, 220-224.
20. Kukielka, E. & A. I. Cederbaum: NADH-dependent microsomal interaction with ferric complexes and production of reactive oxygen intermediates. Arch. Biochem. Biophys. 1989, 275, 540-550.
21. Liu, Y., D. A. Peterson, H. Kimura & D. Schubert: Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction. J. Neurochem. 1997, 69, 581-593.
22. Marklund, S., K. Grankvist & I.-B. Täljedal: Oxy-radicals in the toxicity of cellular toxins. In: Oxy radicals and their scavenger systems. Eds.: R. A. Greenwald & G. Cohen. Elsevier Science Publishing, New York, USA, 1983, Vol II, pp. 96-104.
23. Misra, H. P. & L. D. Gorsky: Paraquat and NADPH-dependent lipid peroxidation in lung microsomes. J. Biol. Chem. 1981, 256, 9994-9998.
24. Mosmann, T.: Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assay. J. Immunol. Meth. 1983, 65, 55-63.
25. Ohkawa, H., N. Ohishi & K. Yagi: Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 1979, 95, 351-358.
26. Qian, S. Y. & G. R. Buettner: Iron and dioxygen chemistry is an important route to initiation of biological free radical oxidations: an electron paramagnetic resonance spin trapping study. Free Radic. Biol. Med. 1999, 26, 1447-1456.
27. Roth, R. A., K. B. Wallace, R. H. Alper & M. D. Bailie: Effect of paraquat treatment of rats on disposition of 5-hydroxytryptamine and angiotensin I by perfused lung. Biochem. Pharmacol. 1979, 28, 2349-2355.
28. Sakai, M., K. Yamagami, Y. Kitazawa, N. Takeyama & T. Tanaka: Xanthine oxidase mediates paraquat-induced toxicity on cultured endothelial cells. Pharmacology & Toxicology 1995, 77, 36-40.
29. Shimada, H, K.-I. Hirai, E. Simamura & J. Pan: Mitochondrial NADH-quinone oxidoreductase of the outer membrane is responsible for paraquat cytotoxicity in rat livers. Arch. Biochem. Biophys. 1998, 351, 75-81.
30. Simic, M. G.: Pulse radiolysis in study of oxygen radicals. Meth. Enzymol. 1990, 186, 89-100.
31. Suntres, Z. E. & P. N. Shek: Alleviation fo paraquat-induced lung injury by pretreatment with bifunctional liposomes containing α-tocopherol and glutathione. Biochem. Pharmacol. 1996, 52, 1515-1520.
32. Tampo, Y., M. Tsukamoto & M. Yonaha: Superoxide production from paraquat evoked by exogenous NADPH in pulmonary endothelial cells. Free Radic. Biol. Med. 1999, 27, 588-595.
33. Thomas, J. A., B. Poland & R. Honzatko: Protein sulfhydryls and their role in the antioxidant function of protein S-thiolation. Arch. Biochem. Biophys. 1995, 319, 1-9.
34. Ukai, K. & J. Sekiya: A new staining method for lyases catalyzing cleavage of a C-S bond in sulfur-containing compounds after polyacrylamide gel electrophoreses. Biosci. Biotech. Biochem. 1997, 61, 124-126.
35. Waintrub, M. L., L. S. Terada, C. J. Beehler, B. O. Anderson, J. A. Leff & J. E. Repine: Xanthine oxidase is increased and contributes to paraquat-induced acute lung injury. J. Appl. Physiol. 1990, 68, 1755-1757.
36. Whiteman, M. & B. Halliwell: Thiourea and dimethylthiourea inhibit peroxynitrite-dependent damage: nonspecificity as hydroxyl radical scavengers. Free Radic. Biol. Med. 1997, 22, 1309-1312.
37. 3+ chelates and ferritin: enhancement by adriamycin, paraquat, menadione, and anthraquinone 2-sulfonate and inhibition by oxygen. Arch. Biochem. Biophys. 1988, 267, 606-613.
38. 2. FEBS Lett. 1981, 128, 339-342.
39. Winterbourn, C. C.: Superoxide as an intracellular radical sink. Free Radic. Biol. Med. 1993, 14, 85-90.
40. Zerez, C. R., S. J. Lee & K. R. Tanaka: Spectrophotometric determination of oxidized and reduced pyridine nucleotides in erythrocytes using a single extraction procedure. Anal. Biochem. 1987, 164, 367-373.
41. Zulueta, J. J., F.-S. Yu, I. A. Hertig, V. J. Thannickal & P. M. Hassoun: Release of hydrogen peroxide in response to hypoxia-reoxygenation: role of an NAD(P)H oxidase-like enzyme in endothelial cell plasma membrane. Amer. J. Respir. Cell Mol. Biol. 1995, 12, 41-49.
42. Öllinger, K. & A. Brunmark: Effect of different oxygen pressures and N,N′-diphenyl-p-phenylenediamine on adriamycin toxicity to cultured neonatal rat heart myocytes. Biochem. Pharmacol. 1994, 48, 1707-1715.