Somatic segregation errors predominantly contribute to the gain or loss of a paternal chromosome leading to uniparental disomy for chromosome 15

Clinical Genetics

Volumn 57, Issue 5, 2000, Pages 349-358

  Robinson, Wendy P ^a,f   Christian, Susan L ^b   Kuchinka, Brian D ^a   Peñaherrera, Maria S ^a   Das, Soma ^b   Schuffenhauer, Simone ^c   Malcolm, Susan ^d   Schinzel, Albert A ^g   Hassold, Terry J ^e   Ledbetter, David H ^b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF CHICAGO   (United States)

^c LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^d Institute for Child Health   (United Kingdom)

^e CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f CHILDREN S AND WOMEN S HEALTH CENTRE OF BRITISH COLUMBIA   (Canada)

^g NONE

Author keywords

Angelman syndrome; Meiosis; Mosaicism; Non disjunction; Prader Willi syndrome; Uniparental disomy; X chromosome inactivation

Indexed keywords

ADULT; AGE; ARTICLE; CHROMOSOME 15; CHROMOSOME DUPLICATION; CHROMOSOME LOSS; CHROMOSOME SEGREGATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GAMETE; GENETIC COMPLEMENTATION; HUMAN; MALE; MEIOSIS; NONDISJUNCTION; PRIORITY JOURNAL; TRISOMY; UNIPARENTAL DISOMY; X CHROMOSOME INACTIVATION; ZYGOTE;

ADULT; ANEUPLOIDY; ANGELMAN SYNDROME; CHROMOSOME SEGREGATION; CHROMOSOMES, HUMAN, PAIR 15; DNA; FEMALE; GENE SILENCING; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INFANT, NEWBORN; MALE; MATERNAL AGE; MICROSATELLITE REPEATS; MOSAICISM; PATERNAL AGE; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; X CHROMOSOME; ZYGOTE;

EID: 0034096456     PISSN: 00099163     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-0004.2000.570505.x     Document Type: Article

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