Influenza virus-induced encephalopathy: Clinicopathologic study of an autopsied case

Pediatrics International

Volumn 42, Issue 2, 2000, Pages 204-214

  Takahashi, Mitsuo ^a   Yamada, Tatsuo ^a   Nakashita, Yoshio ^b   Saikusa, Hiroaki ^c   Deguchi, Masatune ^d   Kida, Hiroshi ^e   Tashiro, Masato ^f   Toyoda, Tetsuya ^g  

^a FUKUOKA UNIVERSITY   (Japan)

^b Sasebo Shiritsu Sogo Hospital   (Japan)

^c Saikusa Pediatric Clinic   (Japan)

^d Deguchi Pediatric Clinic   (Japan)

^e HOKKAIDO UNIVERSITY   (Japan)

^f NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^g KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Autopsy; Encephalopathy; Immunohistochemistry; Influenza A virus; Reverse transcriptase polymerase chain reaction; Viremia

Indexed keywords

CYTOKINE;

ARTICLE; AUTOPSY; BRAIN DISEASE; CASE REPORT; CENTRAL NERVOUS SYSTEM INFECTION; CHILD; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLUENZA; INFLUENZA VIRUS A; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIREMIA; VIRUS DETECTION; VIRUS ENCEPHALITIS; VIRUS GENOME; VIRUS INFECTION;

ANTIGENS, VIRAL; BRAIN DISEASES; CADAVER; CHILD, PRESCHOOL; FEMALE; HEMAGGLUTININS; HUMANS; IMMUNOHISTOCHEMISTRY; INFLUENZA A VIRUS; INFLUENZA, HUMAN; POLYMERASE CHAIN REACTION;

EID: 0034096046     PISSN: 13288067     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1442-200X.2000.01203.x     Document Type: Article

References (37)

1. 1 Hayase Y, Tobita K. Influenza virus and neurological disease. Psychiatry Clin. Neurosci 1997; 51: 181-4.
2. 2 Lin SK, Lu CS, Vingerhoets F et al. Isolated involvement of substantia nigra in acute transient parkinsonism: MRI and PET observations. Parkinson. Relat. Disord. 1995; 1: 67-72.
3. 3 Takahashi M, Yamada T, Nakajima S, Nakajima K, Yamamoto T, Okada H. The substantia nigra is a major target for neurovirulent influenza A virus. J. Exp. Med. 1995; 181: 2161-9.
4. 4 Yamada T, Yamanaka I, Takahashi M, Nakajima S. Invasion of brain by neurovirulent influenza A virus after intranasal inoculation. Parkinson. Relat. Disord. 1996; 2: 187-93.
5. 5 Takahashi M, Yamada T, Nakanishi K et al. Influenza A virus infection of primary cultured cells from rat fetal brain. Parkinson. Relat. Disord. 1997; 3: 97-102.
6. 6 Takahashi M, Yamada T. Influenza A virus and Parkinson's disease. Neurosci. News 1999; 2: 93-101.
7. 7 Protheroe SM, Mellor DH. Imaging in influenza A encephalitis. Arch. Dis. Child. 1991; 66: 702-5.
8. 8 Nagai T, Yugishita A, Tsuchiya Y, Asamura S, Kurokawa H, Matsuo N. Symmetrical thalamic lesions on CT in influenza A virus infection presenting with or without Reye syndrome. Brain Dev. 1993; 15: 67-74.
9. 9 Wang HS, Huang SC. Infantile panthalamic infaret with a striking sonographic findings: the 'bright thalamus'. Neuroradiology 1993; 35: 92-6.
10. 10 Yagishita A, Nakano I, Ushioda T, Otsuki N, Hasegawa A. Acute encephalopathy with bilateral thalamotegmental involvement in infants and children: Imaging and pathological findings. Am. J. Neuroradiol. 1995; 16: 439-47.
11. 11 Kimura S, Ohtuki N, Nezu A, Tanaka M, Takeshita S. Clinical and radiological variability of influenza-related encephalopathy or encephalitis. Acta Paediatr Jpn. 1998; 40: 264-70.
12. 12 Reye RDK, Morgan G, Baral J. Encephalopathy and fatty degeneration of the viscera - A disease entity in childhood. Lancet 1963; ii: 749-52.
13. 13 Levin M, Hjelm M, Kay JDS et al. Haemorrhagic shock and encephalopathy: A new syndrome with a high mortality in young children. Lancet 1983; ii: 64-7.
14. 14 Mizuguchi M, Abe J, Mikkaichi K et al. Acute necrotising encephalopathy of childhood: A new syndrome presenting with multifocal, symmetric brain lesions. J. Neurol. Neurosurg. Psychiatry 1995; 58: 555-61.
15. 15 Mizuguchi M. Acute necrotizing encephalopathy of childhood: A novel form of acute encephalopathy prevalence in Japan and Taiwan. Brain Dev. 1997; 19: 81-92.
16. 16 Yoshikawa H, Watanabe T, Abe T, Oda Y. Clinical diversity in acute necrotizing encephalopathy. J. Child Neurol. 1999; 14: 249-55.
17. 17 Subbarao K, Klimov A, Katz J et al. Characterization of an avian influenza A (H5NI) virus isolated from a child with a fatal respiratory illness. Science 1998; 279: 393-6.
18. 18 Zhao B, Schwartz JP. Involvement of cytokines in normal CNS development and neurological disease: Recent progress and perspectives. J. Neurosci. Res. 1998; 52: 7-16.
19. 19 Sauder C, de la Torre JC. Cytokine expression in the rat central nervous system following perinatal Borna disease virus infection. J. Neuroimmunol. 1999; 96: 29-45.
20. 20 Tsuruoka H, Xu H, Kuroda K et al. Detection of influenza virus RNA in peripheral blood mononuclear cells of influenza patients. Jpn. J. Med. Sci. Biol. 1997; 50: 27-34.
21. 21 Nagai Y. Protease-dependent virus tropism and pathogenicity. Trends Microbiol. 1993; 1: 81-7.
22. 22 Nishino A, Suzuki M, Yoshimoto T, Otani H, Nagura H. A novel aspect of thrombin in the tissue reaction following central nervous system injury. Acta Neurochir (Suppl.) 1994; 60: 86-8.
23. 23 Toms GL, Bird RA, Kingsman SM, Sweet C, Smith H. The behaviour in ferrets of two closely related clones of influenza virus differing virulence for men. Br. J. Exp. Pathol. 1976; 57: 37-48.
24. 24 Smith H, Sweet C. Lessons for human influenza from pathogenicity studies with ferrets. Rev. Infect. Dis. 1988; 10: 56-75.
25. 25 Naficy K. Human influenza infection with proved viremia. N. Engl. J. Med. 1963; 269: 964-6.
26. 26 Mori I, Komatsu T, Takeuchi K, Nakakuki K, Sudo M, Kimura Y. Viremia induced by influenza virus. Microb. Pathos. 1995; 19: 237-44.
27. + memory T cells. J. Immunol. 1996; 157: 3065-73.
28. 28 Stevenson PG, Freeman S, Bangham CRM, Hawke S. Virus dissemination through the brain parenchyma without immunologic control. J. Immunol. 1997; 195: 1876-84.
29. 29 Stevenson PG, Hawke S, Bangham CRM. Protection against influenza virus encephalitis by adoptive lymphocyte transfer. Virology 1997; 232: 158-66.
30. 30 Collie MH, Sweet C, Cavanagh D, Smith H. Association of foetal wastage with influenza infection during ferret pregnancy. Br. J. Exp. Pathol. 1978; 59: 190-5.
31. 31 Cassella JP, Lawrenson JG, Allt G, Firth JA. Ontogeny of four blood-brain barrier markers: An immunocytochemical comparison of pial and cerebral cortical microvessels. J. Anat. 1996; 189: 407-15.
32. 32 Henderson Jr WR. The role of leukotrienes in inflammation. Ann. Intern. Med. 1994; 121: 684-97.
33. 4. Am. J. Pathol. 1987; 126: 19-24.
34. 34 Tilling T, Korte D, Hoheisel D, Galla HJ. Basement membrane protein influence brain capillary endothelial barrier function in vitro. J. Neurochem. 1998; 71: 1151-7.
35. 35 Villanova M, Sewry C, Malandrini A et al. Immunolocalization of several laminin chains in the normal human central and peripheral nervous system. J. Submicrosc. Cytol. Pathol. 1997; 29: 409-13.
36. 36 Villanova M, Malandrini A, Sabatelli P et al. Localization of laminin α2 chain in normal human central nervous system: An immunofluorescence and ultrastructural study. Acta Neuropathol. 1997; 94: 567-71.
37. 37 Morandi L, Di Blasi C, Farina L et al. Clinical correlations in 16 patients with total or partial laminin α2 deficiency characterized using antibodies against 2 fragments of the protein. Arch. Neurol. 1999; 56: 209-15.