Nitric oxide-dependent vasodilatation of rabbit femoral artery by β2-adrenergic stimulation or cyclic AMP elevation in vivo

British Journal of Pharmacology

Volumn 129, Issue 5, 2000, Pages 969-974

  Xu, Biao ^a   Li, Ji ^a   Gao, Lin ^a   Ferro, Albert ^b  

^a MEDICAL SCHOOL OF SOUTHEAST UNIVERSITY   (China)

^b ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

Cyclic AMP; Nitric oxide; Vascular endothelium; Vasodilatation; adrenergic receptors

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 5 [2 [[2 HYDROXY 3 [4 (1 METHYL 4 TRIFLUOROMETHYL 2 IMIDAZOLYL)PHENOXY]PROPYL]AMINO]ETHOXY]SALICYLAMIDE; ARGININE; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BUCLADESINE; CYCLIC AMP; FORSKOLIN; ISOPRENALINE; NITRIC OXIDE;

ANIMAL TISSUE; ARTERIAL PRESSURE; ARTERY DILATATION; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMORAL ARTERY; NONHUMAN; PRIORITY JOURNAL; RABBIT;

ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; BLOOD PRESSURE; BUCLADESINE; CYCLIC AMP; ENZYME INHIBITORS; FEMORAL ARTERY; FORSKOLIN; IMIDAZOLES; ISOPROTERENOL; MUSCLE TONUS; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; PROPANOLAMINES; RABBITS; RECEPTORS, ADRENERGIC, BETA-2; VASODILATION;

EID: 0034092899     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703155     Document Type: Article

References (30)

1. Béa, M.-L., Ghaleh, B., Giudicelli, J.-F. & Berdeaux, A. (1994). Lack of importance of NO in β-adrenoceptor-mediated relaxation of large epicardial canine coronary arteries. Br. J. Pharmacol., 111, 981-982.
2. 2-selective adrenoceptor antagonist (ICI 118,551). J. Cardiovasc. Pharmacol., 5, 430-437.
3. G-monomethyl-L-arginine on the β-adrenoceptor-mediated relaxation of rat mesenteric resistance arteries. Life Sci., 52, PL135-PL139.
4. Buxton, B.F., Jones, C.R., Molenaar, P. & Summers, R.J. (1987). Characterization and autoradiographic localization of β adrenoceptor subtypes in human cardiac tissues. Br. J. Pharmacol., 92, 299-310.
5. Cooke, J.P., Rossitch, E., Andon, N.A., Loscalzo, L. & Dzau, V.J. (1991). Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator. J. Clin. Invest., 88, 1663-1671.
6. Dawes, M., Chowienczyk, PJ. & Ritter, J.M. (1997). Effects of inhibition of the L-arginine / nitric oxide pathway on vasodilation caused by β-adrenergic agonists in human forearm. Circulation, 95, 2293-2297.
7. 2-adrenoceptors in human umbilical vein endothelium in vitro. Br. J. Pharmacol., 126, 1872-1880.
8. G-nitro-L-arginine methyl ester on vasodilator responses to acetylcholine, 5′-N-ethylcarboxamidoadenosine or salbutamol in conscious rats. Br. J. Pharmacol., 103, 1725-1732.
9. Graier, W.F., Groschner, K., Schmidt, K. & Kukovetz, W.R. (1992). Increases in endothelial cyclic AMP levels amplify agonist-induced formation of endothelium-derived relaxing factor (EDRF). Biochem. J., 288, 345-349.
10. Graves, J. & Poston, L. (1993). β-Adrenoceptor agonist mediated relaxation of rat isolated resistance arteries: a role for the endothelium and nitric oxide. Br. J. Pharmacol., 108, 631-637.
11. Gray, D.W. & Marshall, I. (1992). Novel signal transduction pathway mediating endothelium-dependent β-adrenoceptor vasorelaxation in rat thoracic aorta. Br. J. Pharmacol., 107, 684-690.
12. Howell, R.E., Albeda, S.M., Daise, M.L. & Levine, E.M. (1988). Characterization of β-adrenergic receptors in cultured human and bovine endothelial cells. J. Appl. Physiol., 65, 1251-1257.
13. Kamata, K., Miyata, N. & Kasuya, Y. (1989). Involvement of endothelial cells in relaxation and contraction responses of the aorta to isoproterenol in naive and streptozotocin-induced diabetic rats. J. Pharmacol. Exp. Thera., 249, 890-894.
14. 2-adrenoceptors activated by (-) adrenaline in the rat sino-atrial node, Naunyn Schmiedeberg's Arch. Pharmacol., 333, 73-76.
15. Kuchan, M.J. & Francos, J.A. (1994). Role of calcium and calmodulin in flow-induced nitric oxide production in endothelial cells. Am. J. Physiol., 266, C628-C636.
16. Kuriyama, H., Ito, Y., Suzuki, H., Kitamura, K. & Itoh, T. (1982). Factors modifying contraction-relaxation cycle in vascular smooth muscles. Am. J. Physiol., 243, H641-H662.
17. Lefroy, D.C., Donnelly, L.E., Mcewan, J.R. & Macdermot, J. (1993). Phorbol ester enhances activation of adenylate cyclase in bovine aortic endothelial cells. Life Sci., 54, 87-94.
18. 3H-ICI 118,551 and blocking potency of ICI 118,551. Naunyn Schmiedeberg's Arch. Pharmacol., 331, 40-51.
19. Lüscher, T.F. (1991). Endothelium-derived nitric oxide: the endogenous nitrovasodilator in the human cardiovascular system. Eur. Heart J., 12 (Suppl. E): 2-11.
20. Macdonald, P.S., Dubbin, P.M. & Dusting, G.J. (1987). β-Adrenoceptors on endothelial cells do not influence release of relaxing factor in dog coronary arteries. Clin. Exp. Pharmacol. Physiol., 14, 525-534.
21. Molenaar, P., Malta, E., Jones, C.R., Buxton, B.F. & Summers, R.J. (1988). Autoradiographic localization and function of β-adrenoceptors on the human internal mammary artery and saphenous vein. Br. J. Pharmacol., 95, 225-233.
22. Moncada, S. & Higgs, A. (1993). The L-arginine-nitric oxide pathway. N. Engl. J. Med., 329, 2002-2012.
23. Moncada, S., Rees, D.D., Schulz, R. & Palmer, R.M.J. (1991). Development and mechanism of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthesis in vivo. Proc. Natl. Acad. Sci. U.S.A., 88, 2166-2170.
24. Parent, R., Al-Obaidi, M. & Lavallée, M. (1993). Nitric oxide formation contributes to β-adrenergic dilation of resistance coronary vessels in conscious dogs. Circ. Res., 73, 241-251.
25. Priest, R.M., Hucks, D. & Ward, J.P.T. (1997). Noradrenaline. β-adrenoceptor mediated vasorelaxation and nitric oxide in large and small pulmonary arteries of the rat. Br. J. Pharmacol., 122, 1375-1384.
26. Rebich, S., Devine, J.O. & Armstead, W.M. (1995). Role of nitric oxide and cAMP in β-adrenoceptor-induced pial artery vasodilation. Am. J. Physiol., 268, H1071-H1076.
27. Rubanyi, G. & Vanhoutte, P.M. (1985). Endothelium-removal decreases relaxations of canine coronary arteries caused by β-adrenergic agonists and adenosine. J. Cardiovasc. Pharmacol., 7, 139-144.
28. Rubanyi, G.M., Romero, J.C. & Vanhoutte, P.M. (1986). Flowinduced release of endothelium-derived relaxing factor. Am. J. Physiol., 250, H1145-H1149.
29. Steinberg, S.F., Jaffe, E.A. & Bilezikian, J.P. (1984). Endothelial cells contain beta adrenoceptors. Naunyn Schmiedeberg's Arch. Pharmacol., 325, 310-313.
30. Summers, R.J., Molenaar, P., Stephenson, J.A. & Jones, C.R. (1987). Autoradiographic localization of receptors in the mammalian cardiovascular system. Clin. Exp. Pharmacol. Physiol., 14, 437-447.