Neoadjuvant and adjuvant therapy in ductal adenocarcinoma of the pancreas;Neoadjuvante und adjuvante Therapie des duktalen Pankreaskarzinoms

Zentralblatt fur Chirurgie

Volumn 125, Issue 4, 2000, Pages 348-355

  Hohenberger, W ^a   Kastl, Sigrid ^b  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^b NONE

Author keywords

Adjuvant therapy; Neoadjuvant therapy; Pancreatic cancer

Indexed keywords

ANTINEOPLASTIC AGENT;

ARTICLE; CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURVIVAL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; HISTOLOGY; HUMAN; LYMPH NODE DISSECTION; PANCREAS ADENOCARCINOMA; PANCREAS RESECTION; POSTOPERATIVE COMPLICATION; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; STANDARDIZATION; SURGICAL TECHNIQUE; TREATMENT OUTCOME; WEIGHT REDUCTION;

ADENOCARCINOMA; COMBINED MODALITY THERAPY; HUMANS; LYMPH NODE EXCISION; NEOADJUVANT THERAPY; NEOPLASM STAGING; PANCREATECTOMY; PANCREATIC NEOPLASMS; SURVIVAL RATE;

EID: 0034091979     PISSN: 0044409X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (57)

1. Abrams RA, Grochow LB, Chakreavarthy A, Sohn TA, Zahurak ML, Haulk TL, Ord S, Hruban RH, Lillemoe KD, Pitt HA, Caméron JL, Yeo CJ. Intensified adjuvant therapy for pancreatic and periampullary adenocarcinoma: survival results and observations regarding patterns of failure, radiotherapy dose and CA 19-9 levels. Int Radiat Oncol Biol Phys 1999; 44: 1039-1046
2. Andren Sandberg A, Ahren B, Tranberg KG, Bengmark S. Surgical treatment of pancreatic cancer. The Swedish Experience. Int J Pancreatol 1991; 9: 145-151
3. Bakkevold KE, Arnesjö B, Dahl O, Kambestad B. Adjuvant combination chemotherapy (AMF) following radical resection of carcinoma of the pancreas and papilla of Vater - results of a controlled prospective, randomized multicentre study. Eur J Cancer 1993; 5: 698-702
4. Baumel H, Huguier M, Fabre JM. Palliative treatment of cancers of the head of the pancreas. Surgery versus endoscopy. Ann Chir 1995; 49: 110-115, discussion 116
5. Beger HG, Büchler MW, Friess H. Surgical results and indications for adjuvant measures in pancreatic cancer. Chirurg 1994; 65: 246-252
6. Bosset JF, Pavy IJ, Gillet M, Mantion G, Pelissier E, Schraub S. Conventional external irradiation above as adjuvant treatment in resectable pancreatic cancer: results of a prospective study. Radiother Oncol 1992; 24: 191-194
7. Bramhall SR, Neoptolemos JP. Advances in diagnosis and treatment of pancreatic cancer. Gastroenterology 1995; 3: 301-310
8. Bühler L, Niederer HM, Morel P. Pankreaskarzinom: Welche Faktoren bestimmen die Resektabilität. Chir Gastroenterol 1998; 14: 29-31
9. Coia L, Hoffman J, Scher R. Preoperative chemoradiation for adenocarcinoma of the pancreas and duodenum. Int J Rad Oncol Biol Phys 1994; 30: 161-167
10. Condie JD, Nagpal S, Peebles SA. Surgical treatment for ductal adenocarcinoma of the pancreas. Surg Gynecol Obstet 1989; 168: 437-445
11. Di Carlo V, Zerbi A, Balzano G, Villa E. Intraoperative and postoperative radiotherapy in pancreatic cancer. Int J Pancreatol 1997; 21: 53-58
12. Dobelbower RR, Merrick HW, Khuder S, Battle J, Herron LM, Pawlicki T. Adjuvant radiation therapy for pancreatic cancer: A 15-year experience. Int J Rad Oncol Biol Phys 1997; 39: 31-37
13. Eble MJ, Maurer U. Intraoperative und perkutane Radiotherapie des Pankreaskarzinoms. Radiologe 1996; 36: 441-445
14. Foo ML, Gunderson LL, Nagorney DM. Patterns of failure in grossly resected pancreatic ductal adenocarcinoma treated with adjuvant irradiation +/-5-fluorouracil. Int J Rad Oncol Biol Phys 1993; 25: 483-489
15. Friess H, Gassmann M, Büchler MW. Adjuvant therapy of pancreatic cancer using monoclonal antibodies and immune response modifiers. Int J Pancreatol 1997; 21: 43-52
16. Gansauge F, Link KH, Rilinger N, Kunz R, Beger HG. Adjuvante regionale Chemotherapie beim resezierten fortgeschrittenen Pankreaskarzinom. Chirurg 1996; 67: 362-365
17. Gastrointestinal Tumour Study Group (GITSG). Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer. Cancer 1987; 59: 2006-2010
18. Gebauer T, Ridwelski K, Fahlke J, Lippert H. Locoregional and systemic therapy of advanced pancreatic carcinoma. Langenbecks Arch Chir (Suppl Kongressbd) 1998; 115: 1344-1347
19. Glaser K, Klingler P, Bodner E, Klingler A. Die Wertigkeit der intraoperativen Bestrahlung beim duktalen Pankreaskarzinom. Chir Gastroenterol 1995; 11: 139-143
20. Glimelius B, Hoffman K. Sjödén PO, Jacobsson G, Sellström H, Enander LK, Linné T, Svensson C. Chemotherapy improves survival and quality of life in advanced pancreatic and biliary cancer. Ann Oncol 1996; 7: 593-600
21. Grace PA, Pitt HA, Tompkins RK, DenBesten L, Longmire WP Jr. Decreased morbidity and mortality after pancreatoduodenectomy. Am J Surg 1986; 151: 141-149
22. Griffin JF, Smalley SR, Jewell W, Paradelo JC. Patterns of failure after curative resection of pancreatic carcinoma. Cancer 1980; 66: 56-61
23. Hoffman JP, O'Dwyer P, Agarwal P, Salazar H, Ahmad N. Preoperative chemoradiotherapy for localized pancreatic carcinoma. Cancer Suppl 1995; 78: 592-597
24. Hoffman JP, Lipsitz S, Pisansky T, Weese JL, Solin L, Benson AB. Phase II trial of preoperative radiation therapy and chemotherapy for patients with localized, resectable adenocarcinoma of the pan-creas: An Eastern Cooperative Oncology Group Study. J Clin Oncol 1998; 16: 317-323
25. Hoffman JP, Weese JL, Solin LJ, Engstrom P, Agarwal P, Barber LW, Guttman MC. Utwin S, Salazar H, Eisenberg BL. A pilot study of preoperative chemoradiation for patients with localized adenocarcinoma of the pancreas. Surgery 1995; 169: 71-77
26. Hosotani R, Kogire M, Arii S, Nishimura Y, Hiraoka M, Imamura M. Results of pancreatectomy with radiation therapy for pancreatic cancer. Hepato-Gastroenterology 1997; 44: 1528-1535
27. Ihse I, Andersson R, Axelson J, Hansson L. Kombinationstherapie in der Onkologie (multimodale Behandlung) bei Pankreastumoren. Chirurg 1998; 69: 366-370
28. Imaizumi T, Hanyu F, Harada N, Hatori T, Fukuda A. Extended radical whipple resection for cancer of the pancreatic head: Operative procedure and results. Dig Surg 1998; 15: 299-307
29. Ishikawa O, Ohhigashi H, Sasaki Y, Kabuto T, Fukuda I, Furukawa H, Imaoka S, Iwanaga T. Practical usefulness of lymphatic and connective tissue clearance for the carcinoma of the pancreas head. Ann Surg 1988; 208: 215-220
30. Jessup JM, Steele G, Jr Mayer RJ, Posner M, Busse P, Cady B, Stone M, Jenkins R, Osteen R. Neoadjuvant therapy for unresectable pancreatic adenocarcinoma. Arch Surg 1993; 128: 559-564
31. Johanson JF, Eisen GM. Pancreatic cancer. In; Johanson JF (ed): Gastrointestinal diseases: Risk factors and prevention. Lippincott-Raven Publishers, Philadelphia 1997; pp 255-263
32. Kaiser MH, Ellenberg SS. Pancreatic cancer, adjuvant combined radiation and chemotherapy following curative resection. Arch Surg 1985; 120: 899-903
33. Kamprad F. Adjuvante und neoadjuvante Therapieansätze in der Strahlentherapie des Pankreaskarzinoms. Chir Gastroenterol 1997; 13 (Suppl 1): 46-49
34. Kastl S, Klein P, Herrmann O, Brunner T, Grabenbauer G, Hohenberger W. Neoadjuvante Radiochemotherapie beim fortgeschrittenen, primär nicht resektablen Pankreaskarzinom. Langenbecks Arch Chir 1999; (Suppl Kongressbd) submitted
35. Kayahara M, Nagakawa T, Ueno K, Ohta T, Takeda T, Miyazaki I. An evaluation of radical resection for pancreatic cancer based on the mode of recurrence as determined by autopsy and diagnostic imaging. Cancer 1993; 72: 2118-2123
36. Link KH, Gansauge F, Pillasch J, Rilinger N, Büchler M, Beger HG. Regional treatment of advanced nonresectable or resected pancreatic cancer via celiac axis perfusion. First results of a single institution study. Dig Surg 1994; 11: 414-419
37. Lygidakis NJ, Dedemati G, Spenzaris N, Theodoropoulou M. Unresectable pancreatic cancer: is a multi-modality approach a promising therapeutical alternative. Hepatogastroenterology 1997; 44: 1222-1228
38. Lygidakis NJ, Spentzouris N, Theodoracopoulos M, Dedemadi G, Gemos K, Kyriakou A. Pancreatic resection for pancreatic carcinoma combined with neo- and adjuvant locoregional targeting immunochemotherapy. A prospective randomized study. Hepatogastroenterology 1998; 45: 396-403
39. Manabe T, Oshio G, Baba N, Miyashita T, Asano N, Tamura K, Yamaki K, Nonaka A, Tobe T. Radical pancreatectomy for ductal carcinoma of the head of the pancreas. Cancer 1989; 64: 1132-1137
40. Nagakawa T, Konishi I, Ueno K, Ohta T, Akiyama T, Kanno M, Kayahara M, Miyazaki I. The results and problems of extensive radical surgery for carcinoma of the head of the pancreas. Japanese J Surg 1991; 2(1): 262-267
41. Neoptolemos JP, Baker P, Beger H, Link K, Pederzoli P, Bassi C, Dervenis C, Friess H, Buchler M. Progress report. A randomized multicenter European study comparing adjuvant radiotherapy, 6-month chemotherapy, and combination therapy vs. no-adjuvant treatment in resectable pancreatic cancer (ESPAC-1). Int J Pancreatol 1997; 21: 97-103
42. Neoptolemos JP, Kerr DJ, Beger H, Link K, Pederzoli P, Bassi C, Dervenis C, Fernandez-Cruz L, Lacaine F, Friess H, Büchler M. ESPAC-1 Trial progress report: The European randomized adjuvant study comparing radiochemotherapy, 6 months chemotherapy and combination therapy versus observation in pancreatic cancer. Digestion 1997; 58: 570-577
43. Ozaki H, Kinoshita T, Kosuge T, Yamamoto J, Shimada K, Inoue K, Koyama Y, Mukai K. An aggressive therapeutic approach to carcinoma of the body and tail of the pancreas. Cancer 1996; 77: 2240-2245
44. Roder JD, Stein HJ, Hüttl W, Siewert JR. Pylorus-preserving versus standard pancreaticoduodenectomy: an analysis of 110 pancreatic and periampullary carcinomas. Br J Surg 1992; 79: 152-161
45. Shibamoto Y, Manabe T, Baba N, Sasai K. High dose, external beam and intraoperative radiotherapy in the treatment of resectable und unresectable pancreatic cancer. Int J Radiol Oncol Biol Phys 1990; 19: 605-611
46. Sindelar WF. Clinical experience with regional pancreatectomy for adenocarcinoma oi the pancreas. Arch Surg 1989; 124: 127-138
47. Sperti C, Pasquali C, Piccoli A, Pedrazzoli S. Recurrence after resection for ductal adenocarcinoma of the pancreas. World J Surg 1997; 21: 195-200
48. Spitz FR, Abbruzzese JL, Lee JE, Pisters PWT, Lowy AM, Fenoglio CJ, Cleary KR, Janjan NA, Goswitz MS, Rich TA, Evans DB. Preoperative and postoperative chemoradiation strategies in patients treated with pancreaticoduodenectomy for adenocarcinoma of the pancreas. J Clin Oncol 1997; 15: 928-937
49. Staley CA, Lee JE, Cleary KR, Abbruzzese JL, Fenoglio CJ, Rich TA, Evans DB. Preoperative chemoradiation, pancreaticoduodenectomy, and intraoperative radiation therapy for adenocarcinoma of the head of the pancreas. Am J Surg 1996; 171; 118-124, discussion 124-125
50. Wade TP, Coplin MA, Virgo KS, Johnson FE. Periampullary cancer treatment in U.S. Department of Veterans Affairs hospitals: 1987-1991. Surgery 1994; 116: 819-825, discussion 825-826
51. Wenger FA, Zieren HU, Jacobi CA, Muller JM. Hormontherapie des postoperativ rezidivierten Pankreaskarzinoms mit Octreotid und Tamoxifen. Langenbecks Arch Chir (Suppl Kongressbd) 1998; 115: 1348-1350
52. Westerdahl J, Andren-Sandberg A, Ihse I. Recurrence of exocrine pancreatic cancer - local or hepatic. Hepatogastroenterology 1993; 40: 384-387
53. Whittington R, Bryer MP, Haller DG. Adjuvant therapy of resected adenocarcinoma of the pancreas. Int J Rad Oncol Biol Phys 1991; 21: 1137-1143
54. Willett CG, Lewardrowski K, Warshaw AL, Efird J, Compton CC. Resection margins in carcinoma of the head of the pancreas: implications for radiation therapy. Ann Surg 1993; 217: 144-148
55. Yeo CJ, Abrams RA, Grochow LB, Sohn TA, Ord SE, Hruban RH, Zahurak ML, Dooley WC, Coleman J, Sauter PK, Pitt HA, Lillemoe KD, Cameron JL. Pancreaticoduodenectomy for pancreatic adenocarcinoma: postoperative adjuvant chemoradiation improves survival. Ann Surg 1997; 225: 621-633
56. Yeo CJ, Cameron JL, Lillemoe KD, Sitzmann JV, Hruban RH. Pancreaticoduodenectomy for cancer of the head of the pancreas. 201 patients. Ann Surg 1995; 221: 721-733
57. Yeung RS, Weese JL, Hoffman JP, Solin LJ, Paul AR, Engstrom PF, Litwin S, Kowalysliyn MJ, Eisenberg BL. Neoadjuvant chemoradiation in pancreatic and duodenal carcinoma. A phase II study. Cancer 1993; 72: 2124-2133