Microvessel density as a predictor of PSA recurrence after radical prostatectomy: A comparison of CD34 and CD31

American Journal of Clinical Pathology

Volumn 113, Issue 4, 2000, Pages 555-562

  De La Taille, Alexandre ^a,b   Katz, Aaron E ^a,b   Bagiella, Emilia ^c   Buttyan, Ralph ^a,b   Sharir, Sharon ^a,b   Olsson, Carl A ^a,b   Burchardt, Tatjana ^a,b   Ennis, Ronald D ^b   Rubin, Mark A ^d  

^a Columbia Univ Coll Phys Surgs ^*  (United States)

^b New York Presbyterian Hospital Columbia University Medical Center   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Angiogenesis; Microvessel density; MVD; Neovascularization; Prostate; Prostate carcinoma; Prostatectomy; Recurrence

Indexed keywords

ANTIBODY; CD31 ANTIGEN; CD34 ANTIGEN; PROSTATE SPECIFIC ANTIGEN;

ADULT; AGED; ARTICLE; CANCER RECURRENCE; DENSITY; FOLLOW UP; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MICROVASCULATURE; PREDICTION; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATECTOMY;

EID: 0034089370     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/02w2-ke50-pkef-g2g4     Document Type: Article

References (21)

1. Bostwick DG, Iczkowski KA. Microvessel density in prostate cancer: prognostic and therapeutic utility. Semin Urol Oncol. 1998;16:118-123.
2. Weidner N, Carroll PR, Flax J, et al. Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Am J Pathol. 1993;143:401-409.
3. Hall MC, Troncoso P, Pollack A, et al. Significance of tumor angiogenesis in clinically localized prostate carcinoma treated by external beam radiotherapy. Urology. 1994;44:869-875.
4. Vesalainen S, Lipponen P, Talia M, et al. Tumor vascularity and basement membrane structure as prognostic factors in T1-2M0 prostatic adenocarcinoma. Anticancer Res. 1994;14:709-714.
5. Silberman MA, Partin AW, Veltri RW, et al. Tumor angiogenesis correlates with progression after radical prostatectomy but not with pathologic stage in Gleason sum 5 to 7 adenocarcinoma of the prostate. Cancer. 1997;79: 772-779.
6. Gettman MT, Bergstralh EJ, Blute M, et al. Prediction of patient outcome in pathologic stage T2 adenocarcinoma of the prostate: lack of significance for microvessel density analysis. Urology. 1998;51:79-85.
7. Rubin MA, Buyyounouski M, Bagiella E, et al. Microvessel density in prostate cancer: lack of association with tumor grade, pathologic stage and clinical outcome. Urology. 1999;53:542-547.
8. Deering RE, Bigler SA, Brown M, et al. Microvascularity in benign prostatic hyperplasia. Prostate. 1995;26:111-115.
9. Fregene TA, Khanuja PS, Noto AC, et al. Tumor associated angiogenesis in prostate cancer. Anticancer Res. 1993;13:2377-2381.
10. Bettencourt MC, Bauer JJ, Sesterhenn IA, et al. CD34 immunohistochemical assessment of angiogenesis as a prognostic marker for prostate cancer recurrence after radical prostatectomy. J Urol. 1998;160:459-465.
11. Brawer MK, Deering RE, Brown M, et al. Predictors of pathologic stage in prostatic carcinoma: the role of neovascularity. Cancer. 1994;73:678-687.
12. Earth PJ, Weingartner K, Kohler HH, et al. Assessment of vascularization in prostate carcinoma: a morphometric investigation. Hum Pathol. 1996;27:1306-1310.
13. Bostwick DG, Wheeler TM, Blute M, et al. Optimized microvessel density analysis improves prediction of cancer stage from prostate needle biopsies. Urology. 1996;48:47-57.
14. Rogatsch H, Hittmair A, Reissigl A, et al. Microvessel density in core biopsies of prostatic adenocarcinoma: a stage predictor? J Pathol. 1997;182:205-210.
15. Wakiu S, Furusato M, Itoh T, et al. Tumor angiogenesis in prostatic carcinoma with and without bone marrow metastasis: a morphometric study. J Pathol. 1992;168: 257-262.
16. Campbell SC. Advances in angiogenesis research: relevance to urological oncology. J Urol. 1997;158: 1663-1674.
17. Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell. 1996;86:853-854.
18. Bouck N, Stellmach V, Hsu SC. How tumors become angiogenic. Adv Cancer Res. 1996;68:135-174.
19. Polverini PJ. The pathophysiology of angiogenesis. Crit Rev Oral Bid Med. 1995;6:230-247.
20. Ander SJ, Blomkvist LM, Smeds SP, et al. Revascularisation of human parathyroid tissue transplanted to athymic mice. APMIS. 1997;105:931-940.
21. Roy S, Sarkar C. Ultrastructural study of micro blood vessels in human brain tumors and peritumoral tissue. J Neurooncol. 1989;7:283-292.