CD34 immunohistochemical assessment of angiogenesis as a prognostic marker for prostate cancer recurrence after radical prostatectomy

Journal of Urology

Volumn 160, Issue 2, 1998, Pages 459-465

  Bettencourt, Marie Claude ^b   Bauer, John J ^b   Sesterhenn, Isabella A ^b   Connelly, Roger R ^b   Moul, Judd W ^a  

^a Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center   (United States)

^b NONE

Author keywords

Neovascularization; Prostatectomy; Prostatic neoplasms; Recurrence

Indexed keywords

CD34 ANTIGEN; MONOCLONAL ANTIBODY; PROSTATE SPECIFIC ANTIGEN;

ADULT; AGED; ANGIOGENESIS; ARTICLE; CANCER GRADING; CANCER GROWTH; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MICROVASCULATURE; PRIORITY JOURNAL; PROGNOSIS; PROSTATE CANCER; PROSTATE HYPERTROPHY; PROSTATECTOMY; RACE DIFFERENCE;

EID: 0032323230     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(01)62925-2     Document Type: Article

References (32)

1. Parker, S. L., Tong, T., Bolden, S. and Wingo, P. A.: Cancer statistics, 1997. CA, 47: 5, 1997.
2. Folkman, J.: What is the evidence that tumors are angiogenesis-dependent? J. Natl. Cancer Inst., 82: 4, 1990.
3. Folkman, J.: Tumor angiogenesis: therapeutic implications. New Engl. J. Med., 285: 1182, 1971.
4. Folkman, J.: Angiogenesis and breast cancer. J. Clin. Oncol., 12: 441, 1994.
5. Miettinen, M., Lindenmayer, A. and Chaubal, A.: Endothelial cell markers CD31, CD34, and BNH9 antibody to H- and Y-antigens - evaluation of their specificity and sensitivity in the diagnosis of vascular tumors and comparison with von Willibrand factor. Mod. Path., 7: 82, 1994.
6. Fina, L., Molgaard, H., Robertson, D., Bradley, N. J., Monaghan, P., Delia, D., Sutherland, D. R., Baker, M. A. and Greaves, M. F.: Expression of the CD34 gene in vascular endothelial cells. Blood, 75: 2417, 1990.
7. Reinders, J. M., de Groot, G. P., Sixma, J. J., van Mourik, J. A.: Storage and secretion of von Willibrand factor by endothelial cells. Haemostasis, 18: 246, 1988.
8. Burgdorf, W. H., Mukai, K. and Rosai, J.: Immunohistochemical identification of factor VIII-related antigen in endothelial cells of cutaneous lesions of alleged vascular nature. Amer. J. Clin. Path., 75: 167, 1981.
9. Bigler, S. A., Deering, R. E. and Brawer, M. K.: Comparison of microscopic vascularity in benign and malignant prostate tissue. Hum. Path., 24: 220, 1993.
10. Brawer, M. K., Deering, R. E., Brown, M., Preston, S. D. and Bigler, S. A.: Predictors of pathologic stage in prostatic carcinoma: the role of neovascularity. Cancer, 73: 678, 1994.
11. Weidner, N., Carroll, P. R., Flax, J., Blumenfeld, W. and Folkman, J.: Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Amer. J. Path., 143: 401, 1993.
12. Bostwick, D. G., Wheeler, T. M., Blute, M., Barrett, D. M., MacLennan, G. T., Sebo, T. J., Scardino, P. T., Humphrey, P. A., Hudson, M. A., Fradet, Y., Miller, G. J., Crawford, E. D., Blumenstein, B. A., Mahran, H. E. and Miles, B. J.: Optimized microvessel density analysis improves prediction of cancer stage from prostate needle biopsies. Urology, 48: 47, 1996.
13. Silberman, M. A., Partin, A. W., Veltri, R. W. and Epstein, J. I.: Tumor angiogenesis correlates with progression after radical prostatectomy but not with pathologic stage in Gleason sum 5 to 7 adenocarcinoma of the prostate. Cancer, 79: 772, 1996.
14. Weidner, N., Semple, J. P., Welch, W. R. and Folkman, J.: Tumor angiogenesis and metastasis - correlation in invasive breast carcinoma. New Engl. J. Med., 324: 1, 1991.
15. Partin, A. W. and Oesterling, J. E.: The clinical usefulness of prostate specific antigen: update 1994. J. Urol., 152: 1358, 1994.
16. Gleason, D. F.: Histological grading and clinical staging of prostate carcinoma. In: Urologie Pathology: The Prostate. Edited by M. Tannenbaum, Philadelphia: Lea & Febiger, pp. 171-197, 1977.
17. Mostofi, F. K., Sesterhenn, I. A. and Sobin, L. H.: Histological Typing of Prostate Tumors. Geneva: World Health Organization, 1980.
18. Obovi, M., Wheeler, T. M. and Scardino, P. T.: The American Joint Committee on Cancer and International Union Against Cancer TNM classification of prostate cancer. Clinicopathologic correlations. Cancer, 73: 104, 1994.
19. Bauer, J., Sesterhenn, I., Mostofi, F. K., McLeod, D., Srivastava, S. and Moul, J.: p53 Nuclear protein expression is an independent prognostic marker in clinically localized prostate cancer patients undergoing radical prostatectomy. CA, 1: 1295, 1995.
20. Bettencourt, M. C., Bauer, J. J., Sesterhenn, I. A., Mostofi, F. K., McLeod, D. G. and Moul, J. W.: Ki-67 expression is a prognostic marker of recurrence after radical prostatectomy. J. Urol., 156: 1064, 1996.
21. Folkman, J. and Haudenschild, C.: Angiogenesis in vitro. Nature, 288: 551, 1980.
22. Folkman, J. and Cotran, R.: Relation of vascular proliferation to tumor growth. Int. Rev. Exp. Path., 16: 207, 1976.
23. Minchenko, A., Bauer, T., Salceda, S. and Caro, J.: Hypoxic stimulation of vascular endothelial growth factor expression in vitro and in vivo. Lab. Invest., 71: 374, 1994.
24. Siegal, J. A., Yu, E. and Brawer, M. K.: Topography of neovascularity in human prostate carcinoma. CA, 75: 2545, 1995.
25. Folkman, J., Watson, K., Ingber, D. and Hanahan, D.: Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature, 339: 58, 1989.
26. Weidner, N., Folkman, J., Pozza, F., Bevelacqua, P., Allred, E. N., Moore, D. H., Meli, S. and Gasparini, G.: Tumor angiogenesis: a new significant and independent prognostic indicator in early-stage breast carcinoma. J. Natl. Cancer Inst., 84: 1875, 1992.
27. Chodak, G., Haudenschild, C., Gittes, R. F. and Folkman, J.: Angiogenic activity as a marker of neoplastic and preneoplastic lesions of the bladder. Ann. Surg., 192: 762, 1980.
28. Sillman, F., Boyce, J. and Fruchter, R.: The significance of atypical vessels and neovascularization in cervical neoplasia. Amer. J. Obst. Gynec., 139: 154, 1981.
29. Srivastava, A., Laidler, P., Davies, R., Horgan, K. and Hughes, L.: The prognostic significance of tumor vascularity in intermediate-thickness (0.76-4.0 mm. thick) of skin melanoma. A quantitative histologic study. Amer. J. Path., 133: 419, 1988.
30. Hall, M. C., Troncoso, P., Pollack, A., Zhau, H. Y., Zagars, G. K., Chung, L. N. and von Eschenbach, A. G.: Significance of tumor angiogenesis in clinically localized prostate carcinoma treated with external beam radiotherapy. Urology, 44: 869, 1994.
31. Spitz, A., Bochner, B. H., Groschen, S., Young, L., Skinner, D. G., Nichols, P. N., Lieskovsky, G. and Cote, R. J.: Prostate angiogenesis: correlation of microvessel density of needle biopsies and prostatectomy specimens. J. Urol., part 2, 157: 120, abstract 470, 1997.
32. Miles, B., Katten, M. W., Scardino, P. T., Wheeler, T. M., de Vere White, R. W., Gandour-Edwards, R., Humphrey, P. A., Hudson, M. A., Fradet, Y., Mahan, H. E. and Bostwick, D. G.: Optimized microvessel density is associated with recurrence. J. Urol., part 2, 157: 297, abstract 1157, 1997.