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Volumn 440, Issue 2, 2000, Pages 315-321

The effects of inhibiting myosin light chain kinase on contraction and calcium signalling in human and rat myometrium

Author keywords

Ca2+ calmodulin MLCK pathway; ML 9; Myosin light chain kinase; Uterine contraction; Wortmannin

Indexed keywords

1 (5 CHLORO 1 NAPHTHALENESULFONYL)HEXAHYDRO 1H 1,4 DIAZEPINE; CALCIUM; MYOSIN; MYOSIN LIGHT CHAIN KINASE; OXYTOCIN; WORTMANNIN;

EID: 0034086180     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240051054     Document Type: Article
Times cited : (34)

References (28)
  • 1
    • 0027432424 scopus 로고
    • Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: The role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses
    • 1. Arcaro A, Wymann MP (1993) Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses. Biochem J 296:297-301
    • (1993) Biochem J , vol.296 , pp. 297-301
    • Arcaro, A.1    Wymann, M.P.2
  • 2
    • 0031687258 scopus 로고    scopus 로고
    • 2+], electrical activity and force in phasic smooth muscle
    • 2+], electrical activity and force in phasic smooth muscle. Pflügers Arch 436:801-803
    • (1998) Pflügers Arch , vol.436 , pp. 801-803
    • Burdyga, T.V.1    Wray, S.2
  • 3
    • 0030013373 scopus 로고    scopus 로고
    • Wortmannin inhibits contraction without altering electrical activity in canine gastric smooth muscle
    • 3. Burke EP, Gerthoffer WT, Sanders KM, Publicover NG (1996) Wortmannin inhibits contraction without altering electrical activity in canine gastric smooth muscle. Am J Physiol 270: C1405-C1412
    • (1996) Am J Physiol , vol.270 , pp. C1405-C1412
    • Burke, E.P.1    Gerthoffer, W.T.2    Sanders, K.M.3    Publicover, N.G.4
  • 6
    • 0023917890 scopus 로고    scopus 로고
    • ML-9 inhibits the vascular contraction via the inhibition of myosin light chain phosphorylation
    • 6. Ishikawa T, Chijiwa T, Hagiwara M, Mamiya S, Saitoh M, Hidaka H (1998) ML-9 inhibits the vascular contraction via the inhibition of myosin light chain phosphorylation. Mol Pharmacol 33:598-603
    • (1998) Mol Pharmacol , vol.33 , pp. 598-603
    • Ishikawa, T.1    Chijiwa, T.2    Hagiwara, M.3    Mamiya, S.4    Saitoh, M.5    Hidaka, H.6
  • 11
    • 4243278525 scopus 로고    scopus 로고
    • The effect of wortmannin, an inhibitor of myosin light chain kinase (MLCK) on calcium and contraction in isolated human and rat myometrium
    • 11. Longbottom ER, Kupittayanant S, Luckas MJM, Badrick E, Shmigol A, Wray S (1999) The effect of wortmannin, an inhibitor of myosin light chain kinase (MLCK) on calcium and contraction in isolated human and rat myometrium. J Physiol (Lond) 521:65P
    • (1999) J Physiol (Lond) , vol.521 , pp. 65P
    • Longbottom, E.R.1    Kupittayanant, S.2    Luckas, M.J.M.3    Badrick, E.4    Shmigol, A.5    Wray, S.6
  • 12
    • 0025073246 scopus 로고
    • Myosin light chain phosphorylation in human myometrial smooth muscle
    • 12. Mackenzie LW, Word RA, Casey RL, Stull JT (1990) Myosin light chain phosphorylation in human myometrial smooth muscle. Am J Physiol 258:C92-C98
    • (1990) Am J Physiol , vol.258 , pp. C92-C98
    • Mackenzie, L.W.1    Word, R.A.2    Casey, R.L.3    Stull, J.T.4
  • 14
    • 0030662128 scopus 로고    scopus 로고
    • Expression of smooth muscle myosin heavy chains and unloaded shortening in single smooth muscle cells
    • 14. Meer DP, Eddinger TJ (1997) Expression of smooth muscle myosin heavy chains and unloaded shortening in single smooth muscle cells. Am J Physiol 273:C1259-C1266
    • (1997) Am J Physiol , vol.273 , pp. C1259-C1266
    • Meer, D.P.1    Eddinger, T.J.2
  • 15
    • 0023126566 scopus 로고
    • Effects of myosin light-chain kinase inhibitor on catecholamine secretion from rat pheochromocytoma PC12h cells
    • 15. Nagatsu T, Suzuki H, Kiuchi K, Saitoh M, Hidaka H (1987) Effects of myosin light-chain kinase inhibitor on catecholamine secretion from rat pheochromocytoma PC12h cells. Biochem Biophys Res Commun 143:1045-1048
    • (1987) Biochem Biophys Res Commun , vol.143 , pp. 1045-1048
    • Nagatsu, T.1    Suzuki, H.2    Kiuchi, K.3    Saitoh, M.4    Hidaka, H.5
  • 18
    • 0028954711 scopus 로고
    • Oxytocin stimulates mitogen-activated protein kinase activity in cultured human puerperal uterine myometrial cells
    • 18. Ohmichi M, Koike K, Nohara A, Kanda Y, Sakamoto Y, Xian Z, Zhang ZX, Hirota K, Miyake A (1995) Oxytocin stimulates mitogen-activated protein kinase activity in cultured human puerperal uterine myometrial cells. Endocrinology 136:2082-2087
    • (1995) Endocrinology , vol.136 , pp. 2082-2087
    • Ohmichi, M.1    Koike, K.2    Nohara, A.3    Kanda, Y.4    Sakamoto, Y.5    Xian, Z.6    Zhang, Z.X.7    Hirota, K.8    Miyake, A.9
  • 20
    • 0023644877 scopus 로고
    • Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase
    • 20. Saitoh M, Ishikawa T, Matsushima S, Naka M, Hidaka H (1987) Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase. J Biol Chem 16:7796-7801
    • (1987) J Biol Chem , vol.16 , pp. 7796-7801
    • Saitoh, M.1    Ishikawa, T.2    Matsushima, S.3    Naka, M.4    Hidaka, H.5
  • 21
    • 0028043535 scopus 로고
    • Signal transduction and regulation in smooth muscle
    • 21. Somlyo AP, Somlyo AV (1994) Signal transduction and regulation in smooth muscle. Nature 372:231-236
    • (1994) Nature , vol.372 , pp. 231-236
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 26
    • 0032588022 scopus 로고    scopus 로고
    • 2+-dependent contraction in swine carotid artery by myosin kinase inhibitors
    • 2+-dependent contraction in swine carotid artery by myosin kinase inhibitors. Gen Pharmacol 32:483-494
    • (1999) Gen Pharmacol , vol.32 , pp. 483-494
    • Wingard, C.J.1    Murphy, R.A.2
  • 27
    • 0028944015 scopus 로고
    • Myosin phosphorylation and the control of myometrial contraction/relaxation
    • 27. Word RA (1995) Myosin phosphorylation and the control of myometrial contraction/relaxation. Semin Perinatol 19:3-14
    • (1995) Semin Perinatol , vol.19 , pp. 3-14
    • Word, R.A.1
  • 28
    • 0027463826 scopus 로고
    • Uterine contraction and physiological mechanisms of modulation
    • 28. Wray S (1993) Uterine contraction and physiological mechanisms of modulation. Am J Physiol 264:C1-C18
    • (1993) Am J Physiol , vol.264 , pp. C1-C18
    • Wray, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.