Genetic instability in intestinal metaplasia is a frequent event leading to well-differentiated early adenocarcinoma of the stomach

European Journal of Cancer

Volumn 36, Issue 9, 2000, Pages 1113-1119

  Kobayashi, K ^a   Okamoto, T ^a   Takayama, S ^a   Akiyama, M ^a   Ohno, T ^a   Yamada, H ^a  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

BAX; Gastric cancer; hMSH3; hMSH6; Loss of heterozygosity; Microsatellite instability; Replication error; TGF RII

Indexed keywords

PROTEIN BCL 2; TAQ POLYMERASE; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ADULT; AGED; ARTICLE; CARCINOGENESIS; CLINICAL ARTICLE; FEMALE; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; INTESTINE METAPLASIA; MALE; MICROSATELLITE INSTABILITY; MULTIPLE PREGNANCY; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STOMACH ADENOCARCINOMA;

ADENOCARCINOMA; AGED; BASE PAIR MISMATCH; FEMALE; FRAMESHIFT MUTATION; HUMANS; INTESTINES; JAPAN; LOSS OF HETEROZYGOSITY; MALE; METAPLASIA; MICROSATELLITE REPEATS; MIDDLE AGED; STOMACH NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 0034085968     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(00)00066-6     Document Type: Article

References (35)

1. Parkin D.M., Pisani P., Ferlay J. Estimates of the worldwide incidence of eighteen major cancers in 1985. Int. J. Cancer. 54:1993;594-606.
2. Lauren P. The two histological main types of gastric carcinoma. diffuse and so-called intestinal-type carcinoma Acta Pathol. Microbiol. Scand. 64:1965;31-39.
3. Correa P, Shiao Y-H. Phenotypic and genotypic events in gastric carcinogenesis. Cancer Res 1994, 54(Suppl.), 1941s-1943s.
4. Stemmermann G.N. Intestinal metaplasia of the stomach. a status report Cancer. 74:1994;556-564.
5. Fearon E.R., Vogelstein B. A genetic model for colorectal tumorigenesis. Cell. 61:1990;759-767.
6. Ochiai A., Yamauchi Y., Hirohashi S. p53 mutations in the non-neoplastic mucosa of the human stomach showing intestinal metaplasia. Int. J. Cancer. 69:1996;28-33.
7. Nishimura K., Yokozaki H., Haruma K., Kajiyama G., Tahara E. Alterations of the APC gene in carcinoma cell lines and precancerous lesions of the stomach. Int. J. Oncol. 77:1995;587-592.
8. Rhyu M.-G., Park W.-S., Meltzer S.J. Microsatellite instability occurs frequently in human gastric carcinoma. Oncogene. 9:1994;29-32.
9. Chong J.-M., Fukayama M., Hayashi Y.et al. Microsatellite instability in the progression of gastric carcinoma. Cancer Res. 54:1994;4595-4597.
10. Lin J.-T., Wu M.-S., Shun C.-T.et al. Microsatellite instability in gastric carcinoma with special references to histopathology and cancer stages. Eur. J. Cancer. 31A:1995;1879-1882.
11. Chung Y.-J., Song J.-M., Lee J.-Y.et al. Microsatellite instability-associated mutations associate preferentially with the intestinal type of primary gastric carcinomas in a high-risk population. Cancer Res. 56:1996;4662-4665.
12. Dos Santos N.R., Seruca R., Constancia M., Seixas M., Sobrinho-Simoes M. Microsatellite instability at multiple loci in gastric carcinoma. clinicopathologic implications and prognosis Gastroenterology. 110:1996;38-44.
13. Fishel R., Lescoe M.K., Rao M.R.S.et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell. 75:1993;1027-1038.
14. Bronner C.E., Baker S.M., Morrison P.T.et al. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature. 368:1994;258-261.
15. Nicolaides N.C., Papadopoulos N., Liu B.et al. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature. 371:1994;75-80.
16. Thibodeau S.N., Bren G., Schaid D. Microsatellite instability in cancer of the proximal colon. Science. 260:1993;816-819.
17. Peltomäki P., Aaltonen L.A., Sistonen P.et al. Genetic mapping of a locus predisposing to human colorectal cancer. Science. 260:1993;810-812.
18. Markowitz S., Wang J., Myeroff L.et al. Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability. Science. 268:1995;1336-1338.
19. Ohue M., Tomita N., Monden T.et al. Mutations of the transforming growth factor β type II receptor gene and microsatellite instability in gastric cancer. Int. J. Cancer. 68:1996;203-206.
20. Renault B., Calistri D., Buonsanti G., Nanni O., Amadori D., Ranzani G.N. Microsatellite instability and mutations of p53 and TGF-β RII genes in gastric cancer. Hum. Genet. 98:1996;601-607.
21. Rampino N., Yamamoto H., Ionov Y.et al. Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype. Science. 275:1997;967-969.
22. Chung Y.-J., Park S.-W., Song J.-M.et al. Evidence of genetic progression in human gastric carcinomas with microsatellite instability. Oncogene. 15:1997;1719-1726.
23. Malkhosyan S., Rampino N., Yamamoto H., Perucho M. Frameshift mutator mutations. Nature. 382:1996;499-500.
24. Yamamoto H., Sawai H., Perucho M. Frameshift somatic mutations in gastrointestinal cancer of the microsatellite mutator phenotype. Cancer Res. 57:1997;4420-4426.
25. Vasen H.F.A., Mecklin J.-P., Khan P.M., Lynch H.T. Hereditary non-polyposis colorectal cancer. Lancet. 338:1991;877.
26. Japanese classification of gastric carcinoma. Second English Edition. Gastric Cancer. 1:1998;10-24.
27. Sobin L.H., Wittekind Ch. TNM Classification of Malignant Tumours. 5th ed. 1997;Wiley-Liss, Inc, New York.
28. Goeltz S.E., Hamilton S.R., Vogelstein B. Purification of DNA from formaldehyde fixed and paraffin embedded human tissue. Biochem. Biophys. Res. Comm. 130:1985;118-126.
29. Dietmaier W., Wallinger S., Bocker T., Kullmann F., Fishel R., Rüschoff J. Diagnostic microsatellite instability. definition and correlation with mismatch repair protein expression Cancer Res. 57:1997;4749-4756.
30. Toh Y., Oki E., Oda S.et al. An integrated microsatellite length analysis using an automated fluorescent DNA sequencer. Cancer Res. 56:1996;2688-2691.
31. Goessl C., Heicappell R., Münker R.et al. Microsatellite analysis of plasma DNA from patients with clear cell renal carcinoma. Cancer Res. 58:1998;4728-4732.
32. Boland C.R., Thibodeau S.N., Hamilton S.R.et al. A national cancer institute workshop on microsatellite instability for cancer detection and familial predisposition. development of international criteria for the determination of microsatellite instability in colorectal cancer Cancer Res. 58:1998;5248-5257.
33. Gleeson C.M., Sloan J.M., McGuigan J.A., Ritchie A.J., Weber J.L., Russell S.E.H. Ubiquitous somatic alterations at microsatellite alleles occur infrequently in Barrett's-associated esophageal adenocarcinoma. Cancer Res. 56:1996;259-263.
34. Hamamoto T., Yokozaki H., Semba S.et al. Altered microsatellite in incomplete-type intestinal metaplasia adjacent to primary gastric cancers. J. Clin. Pathol. 50:1997;841-846.
35. Lengauer C., Kinzler K.W., Vogelstein B. Genetic instabilities in human cancers. Nature. 396:1998;643-649.