Endothelium and endogenous fibrinolysis;Endothel und endogene fibrinolyse

Zeitschrift fur Kardiologie

Volumn 89, Issue 3, 2000, Pages 219-226

  Nordt, T K ^a   Bode, C ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Atherosclerosis; Endothelial cell; PAI 1; Plasminogen; Plasminogen activator

Indexed keywords

PLASMINOGEN; PLASMINOGEN ACTIVATOR; PLASMINOGEN ACTIVATOR INHIBITOR 1;

ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; ENDOTHELIUM CELL; FIBRINOLYSIS; HUMAN; KALLIKREIN KININ SYSTEM; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PERIPHERAL VASCULAR DISEASE; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; VASCULAR ENDOTHELIUM;

EID: 0034083702     PISSN: 03005860     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00007321     Document Type: Article

References (36)

1. 1. Ardaillou R (1999) Angiotensin II receptors. J Am Soc Nephrol 10 (suppl. 11):S30-S39
2. 2. Brown NJ, Nadeau JH, Vaughan DE (1997) Selective stimulation of tissue-type plasminogen activator (t-PA) in vivo by infusion of bradykinin. Thromb Haemost 77:522-525
3. 3. Cagliero E, Roth T, Roy S, Maiello M, Lorenzi M (1991) Expression of genes related to the extracellular matrix in human endothelial cells. Differential modulation by elevated glucose concentrations, phorbol esters, and cAMP. J Biol Chem 266:14244-14250
4. 4. Carmeliet P, Moons L, Dewerchin M, Rosenberg S, Herbert JM, Lupu F, Collen D (1998) Receptor-independent role of urokinase-type plasminogen activator in pericellular plasmin and matrix metalloproteinase proteolysis during vascular wound healing in mice. J Cell Biol 140: 233-245
5. 5. Carmeliet P, Moons L, Herbert JM, Crawley J, Lupu F, Lijnen R, Collen D (1997) Urokinase but not tissue plasminogen activator mediates arterial neointima formation in mice. Circ Res 81: 829-839
6. 6. Carmeliet P, Moons L, Lijnen R, Janssens S, Lupu F, Collen D, Gerard RD (1997) Inhibitory role of plasminogen activator inhibitor-1 in arterial wound healing and neointima formation. A gene targeting and gene transfer study in mice. Circulation 96:3180-3191
7. 7. Carmeliet P, Moons L, Ploplis V, Plow E, Collen D (1997) Impaired arterial neointima formation in mice with disruption of the plasminogen gene. J Clin Invest 99:200-208
8. 8. Carmeliet P, Stassen JM, Schoonjans L, Ream B, van den Oord JJ, de Mol M, Mulligan RC, Collen D (1993) Plasminogen activator inhibitor-1 gene-deficient mice. II. Effects on hemostasis, thrombosis, and thrombolysis. J Clin Invest 92:2756-2760
9. 9. Carmeliet P, Stassen JM, Vlaenderen IV, Meidell RS, Collen D, Gerard RD (1997) Adenovirus-mediated transfer of tissue-type plasminogen activator augments thrombolysis in tissue-type plasminogen activator-deficient and plasminogen activator inhibitor-1-overexpressing mice. Blood 90:1527-1534
10. 10. Farrehi PM, Ozaki CK, Carmeliet P, Fay WP (1998) Regulation of arterial thrombolysis by plasminogen activator inhibitor-1 in mice. Circulation 97:1002-1008
11. 11. Fujii S, Sawa H, Sobel BE (1993) Inhibition of endothelial cell expression of plasminogen activator inhibitor type-1 by gemfibrozil. Thromb Haemost 70: 642-647
12. 12. Goodfield NER, Newby DE, Ludlam CA, Flapan AD (1999) Effects of acute angiotensin II type 1 receptor antagonism and angiotensin converting enzyme inhibition on plasma fibrinolytic parameters in patients with heart failure. Circulation 99:2983-2985
13. 13. Hamdan AD, Quist WC, Gagne JB, Feener EP (1996) Angiotensin-converting enzyme inhibition suppresses plasminogen activator inhibitor-1 expression in the neointima of balloon-injured rat aorta. Circulation 93:1073-1078
14. 14. Juhan-Vague I, Alessi MC, Vague P (1991) Increased plasma plasminogen activator inhibitor 1 levels: A possible link between insulin resistance and atherothrombosis. Diabetologia 34:457-462
15. 15. Kato K, Satoh H, Endo Y, Yamada D, Midorikawa S, Sato W, Mizuno K, Fujita T, Tsukamoto K, Watanabe T (1999) Thiazolidinediones down-regulate plasminogen activator inhibitor type 1 expression in human vascular endothelial cells: A possible role for PPAR-gamma in endothelial function. Biochem Biophys Res Comm 258:431-435
16. 16. Klassen KJ, Nordt TK, Schneider DJ, Sobel BE (1993) Constitutive biosynthesis of plasminogen activator inhibitor type-1 (PAI-1) by cultured human aortic endothelial cells independent of insulin. Coronary Artery Disease 4:713-719
17. 17. Lijnen HR, Okada K, Matsuo O, Collen D, Dewerchin M (1999) Alpha2-antiplasmin gene deficiency in mice is associated with enhanced fibrinolytic potential without overt bleeding. Blood 93:2274-2281
18. 18. Maiello M, Boeri D, Podesta F, Cagliero E, Vichi M, Odetti P, Adezati L, Lorenzi M (1992) Increased expression of tissue plasminogen activator and its inhibitor and reduced fibrinolytic potential of human endothelial cells cultured in elevated glucose. Diabetes 41: 1009-1015
19. 19. Matsuno H, Kozawa O, Niwa M, Ueshima S, Matsuo O, Collen D, Uematsu T (1999) Differential role of components of the fibrinolytic system in the formation and removal of thrombus induced by endothelial injury. Thromb Haemosi 81:601-604
20. 20. Medvescek M, Keber D, Stegnar M, Borovnicar A (1990) Plasminogen activator inhibitor 1 response to a carbohydrate meal in obese subjects. Fibrinolysis 4 (suppl 2):89-90
21. 21. Nordt TK, Klassen KJ, Schneider DJ, Sobel BE (1993) Augmentation of synthesis of plasminogen activator inhibitor type-1 in arterial endothelial cells by glucose and its implications for local fibrinolysis. Arterioscler Thromb 13: 1822-1828
22. 22. Nordt TK, Komas K, Peter K, Fujii S, Sobel BE, Kübler W, Bode C (1997) Attenuation by gemfibrozil of expression of plasminogen activator inhibitor type-1 induced by insulin and its precursors. Circulation 95:677-683
23. 22a. Nordt TK, Peter K, Bode C, Sobel BE (2000) Differential regulation by troglitazone of plasminogen activator inhibitor type-1 (PAT-1) in human hepatic and vascular cells. J Clin Endocrinol Metab: in press
24. 23. Nordt TK, Sawa H, Fujii S, Bode C, Sobel BE (1998) Augmentation of arterial endothelial cell expression of the plasminogen activator inhibitor type-1 (PAI-1) gene by proinsulin and insulin in vivo. J Mol Cell Cardiol 30: 1535-1543
25. 24. Nordt TK, Sawa H, Fujii S, Sobel BE (1995) Induction of plasminogen activator inhibitor type-1 (PAI-1) by proinsulin and insulin in vivo. Circulation 91:764-770
26. 25. Ridker PM, Gaboury CL, Conlin PR, Seely EW, Williams GH, Vaughan DE (1993) Stimulation of plasminogen activator inhibitor in vivo by infusion of angiotensin II. Evidence of a potential interaction between the renin-angiotensin system and fibrinolytic function. Circulation 87:1969-1973
27. 26. Schmaier AH (1998) Plasma contact activation: a revised hypothesis. Biol Res 31:251-262
28. 27. Schneider DJ, Absher PM, Ricci MA (1997) Dependence of augmentation of arterial endothelial cell expression of plasminogen activator inhibitor type 1 by insulin on soluble factors released from vascular smooth muscle cells. Circulation 96:2868-2876
29. 28. Schneider DJ, Nordt TK, Sobel BE (1992) Stimulation by proinsulin of expression of plasminogen activator inhibitor type-1 in endothelial cells. Diabetes 41:890-895
30. 29. Smith D, Gilbert M, Owen WG (1985) Tissue plasminogen activator release in vivo in response to vasoactive agents. Blood 66:835-839
31. 30. Sobel BE, Woodcock-Mitchell J, Schneider DJ, Holt RE, Marutsuka K, Gold H (1998) Increased plasminogen activator inhibitor type 1 in coronary artery athereclomy specimens from type 2 diabetic compared with nondiabetic patients. A potential factor predisposing to thrombosis and its persistence. Circulation 97: 2213-2221
32. 31. Vaughan DE, Lazos SA, Tong K (1995) Angiotensin II regulates the expression of plasminogen activator inhibitor-1 in cultured endothelial cells. A potential link between the renia-angiotensin system and thrombosis. J Clin Invest 95: 995-1001
33. 32. Vaughan DE, Rouleau JL, Pfeffer MA (1995) Role of the fibrinolytic system in preventing myocardial infarction. Eur Heart J 16 (suppl K):31-36
34. 33. Vaughan DE, Rouleau JL, Ridker PM, Arnold JMO, Menapace FJ, Pfeffer MA, on behalf of the HEART Study Investigators (1997) Effects of ramipril on plasma fibrinolytic balance in patients with acute anterior myocardial infarction. Circulation 96:442-447
35. 34. Wright RA, Flapan AD, Alberti KGMM, Ludlam CA, Fox KAA (1994) Effects of captopril therapy on endogenous fibrinolysis in men with recent, uncomplicated myocardial infarction. J Am Coll Cardiol 24:67-73
36. 35. Zhu Y, Carmeliet P, Fay WP (1999) Plasminogen activator inhibitor-1 is a major determinant of arterial thrombolysis resistance. Circulation 99:3050-3055