An endogenous melanocyte-inhibiting tripeptide pyroGlu-Phe-GlyNH2 delays in vivo growth of monoclonal experimental melanoma

Cell Proliferation

Volumn 33, Issue 2, 2000, Pages 91-99

  Gembitsky, D S ^a   De Angelis, P M ^b   Reichelt, K L ^b   Elgjo, K ^b  

^a CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

MELANOCYTE INHIBITING TRIPEPTIDE; TRIPEPTIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CANCER TRANSPLANTATION; CELL CLONE; CELL CULTURE; CELL LINE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DNA CONTENT; FEMALE; HUMAN; HUMAN CELL; MELANOCYTE; MELANOMA; MOUSE; NONHUMAN; NUDE MOUSE; SINGLE BLIND PROCEDURE; TUMOR GROWTH;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; CLONE CELLS; DNA, NEOPLASM; FEMALE; GROWTH INHIBITORS; MELANOCYTES; MELANOMA; MICE; MICE, INBRED HRS; NEOPLASM TRANSPLANTATION; OLIGOPEPTIDES; PYRROLIDONECARBOXYLIC ACID; SKIN NEOPLASMS; TUMOR CELLS, CULTURED;

ANIMALIA; MUS MUSCULUS;

EID: 0034082730     PISSN: 09607722     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2184.2000.00166.x     Document Type: Article

References (27)

1. ANGIOLILLO A, BRAMUCCI M, MARSILI V et al. (1993) Phosphorylation of synthetic acidic peptides by casein kinase II: Evidence for competition with phosphorylation of proteins involved in transcription. Mol. Cell. Biochem. 125, 65.
2. BASERGA R, PORCU P, SELL C. (1993) Oncogens, growth factors and control of the cell cycle. Cancer Surv. 16, 201.
3. BRAMUCCI M, MIAMO A, AMICI D. (1992) Epidermal inhibitory pentapeptide phosphorylated in vitro by calf thymus protein kinase N II is protected from serum enzyme hydrolysis. Biochem. Biophys. Res. Commun. 183, 474.
4. 2+ cations. FEBS Lett. 291, 67.
5. ELGJO K. (1993) Pentapeptide growth inhibitors, carcinogenesis, and cancer. In: IVERSEN OH, ed. New Frontiers in Cancer Causation. Washington, DC: Taylor & Francis, 125.
6. ELGJO K, REICHELT KL. (1984) Purification and characterization of a mitosis inhibiting epidermal peptide. Cell Biol. Int. Report 8, 379.
7. ELGJO K, REICHELT KL, GEMBITSKY DS. (1998) Growth-inhibiting N-substituted endogenous peptides. In: MARCIEIRA-COELHO XX, ed. Progress in Molecular and Subcellular Biology, Vol. 20. Berlin Heidelberg New York: Springer Verlag, 143.
8. EPIFANOVA OI, BROOKS RF. (1994) Negative control of cell proliferation in eukariotes. Cell Prolif. 27, 373.
9. GEMBITSKY DS, ANTOKHIN AI, POPOVA NY, PODUSOV YN, ROMANOV YA. (1997) Comparative analysis of radiometric and autoradiographic methods in the investigation of DNA synthetic activity of tumor cells in vitro. Oncol. Report 4, 1301.
10. GEMBITSKY DS, POPOVA NY, ANTOKHIN AI et al. (1996) The Ehrlich ascites carcinoma (EAC) contains 300-500 Da inhibitor(s) suppressing DNA synthesis in cultured EAC cells and EAC cell division in tumor-bearing mice. Oncol. Reports 3, 333.
11. 2 on murine melanocytes: transitory delay of cell growth in vitro and the cell cycle specificity. Exp. Cell Res. 243, 367.
12. GEMBITSKY DS, REICHELT KL, HAAKONSEN P, PAULSEN JE, ELGJO K. (1998b) Identification of a melanocyte growth-inhibiting tripeptide and determination of its structure. J. Peptide Res. 51, 80.
13. GUIGON M, BONNET D. (1995) Inhibitory peptides in hematopoiesis. Exp. Hematol. 23, 477.
14. JOHNSON TC. (1994) Negative regulators of cell proliferation. Pharmacol. Ther. 62, 247.
15. KAWAKAMI Y, ROBBINS PF, WANG RF, PARKHURST M, KANG X, ROSENBERG SA. (1998) The use of melanosomal proteins in the immunotherapy of melanoma. J. Immunother. 21, 237.
16. KAWAKAMI Y, ROBBINS PF, WANG RF, ROSENBERG SA. (1997) Identification of melanoma antigens recognized by T lymphocytes and their use in the immunotherapy of cancer. In: DEVITA VT, HELLMAN S, ROSENBERG SA, eds. Principle and Practice of Oncology, Update. Philadelphia: Lippincott-Raven, 1.
17. KRASAGAKIS K, KRÜGER-KRASAGAKES S, FIMMEL S et al. (1999) Desensitization of melanoma cells to autocrine TGF-β isoforms. J. Cell. Physiol. 178, 179.
18. LENEANT M, WDZIECZAK-BAKALA J, GUITTET E, PROME JC, SOTTY D, FRINDEL E. (1989) Inhibitor of hematopoietic pluripotent stem cell proliferation: purification and determination of its structure. Proc. Natl. Acad. Sci. USA 86, 779.
19. MARSHALL E, LORD BI. (1996) Feedback inhibitors in normal and tumor tissues. Int. Rev. Cytol. 167, 185.
20. MEIER F, SATYAMOORTHY K, NESBIT M et al. (1998) Molecular events in melanoma development and progression. Front. Biosci. 3, D1005.
21. PAUKOVITS WR, LAERUM OD. (1982) Isolation and synthesis of a hemoregulatory peptide. Z. Naturforsch. [C] 37, 1297.
22. PAULSEN JE, REICHELT KL, PETERSEN AK. (1987) Purification and characterization of a growth inhibitory hepatic peptide. Virchow's Arch. B Cell Pathol. 54, 152.
23. SKRAASTAD Ø, FOSSLI T, EDMINSON PD, REICHELT KL. (1987) Purification and characterization of a mitosis inhibitory tripeptide from mouse intestinal extracts. Epithelia 1, 107.
24. SPORN MB, ROBERTS AB. (1985) Autocrine growth factors and cancer. Nature 313, 745.
25. STADELMANN WK, REINTGEN DS. (1998) Prognosis in malignant melanoma. Hematol. Oncol. Clin. North. Am. 12, 767.
26. VINDELÖV LL, CHRISTENSEN IJ, NISSEN NI. (1983) A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis. Cytometry 3, 323.
27. YAMAGUCHI N, ANAND-APTE B, LEE M et al. (1999) Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc binding. EMBO J. 18, 4414.