Synthesis of novel 5H,11H-pyrido[2',3':2,3]thiopyrano[4,3-b]-indoles by Fischer-indole cyclization

Journal of Heterocyclic Chemistry

Volumn 37, Issue 2, 2000, Pages 379-382

  Da Settimo, Antonio ^a   Marini, Anna Maria ^a   Primofiore, Giampaolo ^a   Da Settimo, Federico ^a   Salerno, Silvia ^a   La Motta, Concettina ^a   Pardi, Gianluca ^a   Ferrarini, Pier Luigi ^a   Mori, Claudio ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

5H,11H PYRIDO[2',3':2,3]THIOPYRANO[4,3 B]INDOLE DERIVATIVE; INDOLE DERIVATIVE; PHENYLHYDRAZONE DERIVATIVE; PYRIDONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CYCLIZATION; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS;

EID: 0034078288     PISSN: 0022152X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jhet.5570370224     Document Type: Article

References (14)

1. L. F. Liu, Ann. Rev. Biochem., 58, 351-375 (1989).
2. G. Capranico, M. Binaschi, M. E. Borghetto, F. Zunino, and M. Palumbo, Trends Pharm. Sci., 18, 323-329 (1997).
3. Y. Pommier, G. Capranico, A. Orr, and K. W. Kohn, J. Mol. Biol., 222, 909 (1991).
4. W. A. Denny, Cancer Chemotherapeutic Agents, W. Foye, ed, ACS, Washington D.C, pp 218-239 (1995).
5. U. Pindur and G. Fisher, Curr. Med. Chem, 3, 379 (1996).
6. G. W. Gribble, The Alkaloids, 39, A. Brossi, ed, Academic Press, New York, p 239 (1990).
7. M. Ohashi and T. Oki, Exp. Opin. Ther. Patents, 6, 1285 (1996).
8. M. Y. Vilarem, I. Y. Charcosset, F. Primaux, M. P. Gras, and F. Calvo, Cancer Res., 45, 3906 (1985).
9. A. Da Settimo, G. Primofiore, M. C. Bertacchi, F. Da Settimo, and A. M. Marini, J. Heterocyclic Chem., 32, 941 (1995).
10. A. Da Settimo, A. M. Marini, G. Primofiore, F. Da Settimo, S. Salerno, G. Viola, L. Dalla Via, and S. Marciani Magno, Eur. J. Med. Chem., 33, 685 (1998).
11. F. Chetoni, F. Da Settimo, A. M. Marini, and G. Primofiore, J. Heterocyclic Chem., 30, 1481 (1993).
12. A. Da Settimo, G. Primofiore, G. Biagi, and V. Santerini, J. Heterocyclic Chem., 13, 97 (1976).
13. A. Da Settimo, G. Primofiore, G. Biagi, V. Santerini, and L. D'Amico, J. Org. Chem., 42, 1725 (1977).
14. P. L. Ferrarini, C. Mori, M. Badawneh, V. Calderone, R. Greco, C. Manera, A. Martinelli, P. Nieri, and G. Saccomanni, Eur. J. Med. Chem., in press.