The cyanobacterium Nodularia PCC 7804, of freshwater origin, produces [L-Har2]nodularin

Phytochemistry

Volumn 54, Issue 1, 2000, Pages 57-61

  Beattie, Kenneth A ^a   Kaya, Kunimitsu ^b   Codd, Geoffrey A ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

Author keywords

Blue green algae; Cyanobacteria; Nodularia PCC 7804; Nodularia sphaerocarpa; Nodularin

Indexed keywords

AMINO ACID; CYCLOPEPTIDE; FRESH WATER; NODULARIN; NODULARIN, HAR(2); NODULARIN, HAR(2)-; PENTAPEPTIDE; PHOSPHATASE; TOXIN;

AMINO ACID ANALYSIS; ANIMAL; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; CYANOBACTERIUM; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE;

AMINO ACIDS; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYANOBACTERIA; FRESH WATER; MAGNETIC RESONANCE SPECTROSCOPY; MICE; PEPTIDES, CYCLIC; TOXINS, BIOLOGICAL;

EID: 0034077446     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9422(00)00045-5     Document Type: Article

References (19)

1. Bolch C.J.S., Orr P.T., Jones G.J., Blackburn S.I. Genetic, morphological, and toxicological variation among globally distributed strains of Nodularia (Cyanobacteria). Journal of Phycology. 35:1999;339-355.
2. Carmichael W.W., Eschedor J.T., Patterson G.M.L., Moore R.E. Toxicity and partial structure of a hepatotoxic peptide produced by the cyanobacterium Nodularia spumigena Mertens emend. L575 from New Zealand. Applied and Environmental Microbiology. 54:1988;2257-2263.
3. Codd G.A., Steffensen D.A., Burch M.D., Baker P.D. Toxic blooms of cyanobacteria in Lake Alexandrina, South Australia - learning from history. Australian Journal of Marine and Freshwater Research. 45:1994;731-736.
4. de Silva E.D., Williams D.E., Andersen R.J., Klix H., Holmes C.F.B., Allen T.M. Motuporin, a potent protein phosphatase inhibitor isolated from the Papua New Guinea sponge Theonella swinhoei Gray. Tetrahedron Letters. 33:1992;1561-1564.
5. Eriksson J.E., Meriluoto J.A.O., Kujari H.P., Osterlund K., Fagerlund K., Hallbom L. Preliminary characterization of a toxin isolated from the cyanobacterium Nodularia spumigena. Toxicon. 26:1988;161-166.
6. Francis G. Poisonous Australian lake. Nature (London). 18:1878;11-12.
7. Harding W.R., Rowe N., Wessels J.C., Beattie K.A., Codd G.A. Death of a dog attributed to the cyanobacterial (blue-green alga) hepatotoxin nodularin in South Africa. Journal of the South African Veterinary Association. 66:1995;256-259.
8. Jones G.J., Blackburn S.I., Parker N.S. A toxic bloom of Nodularia spumigena Mertens in Orielton Lagoon, Tasmania. Australian Journal of Marine and Freshwater Research. 45:1994;787-800.
9. Komarek J., Hubel M., Hubel H., Smarda J. The Nodularia studies. Part II: Taxonomy. Archiv fur Hydrobiologie, Suppl. 96, Algological Studies. 68:1993;1-25.
10. Lawton L.A., Edwards C., Codd G.A. Extraction and high-performance liquid chromatographic method for the determination of microcystins in raw and treated waters. The Analyst. 119:1994;1525-1530.
11. Marfey P. Determination of D-amino acids. Part II: Use of a bifunctional reagent 1,5-difluoro-2,4-dinitrobenzene. Carlsberg Research Communications. 49:1984;591-596.
12. Namikoshi M., Choi B.W., Sakai R., Sun F., Rinehart K.L., Carmichael W.W., Evans W.R., Cruz P., Munro M.H.G., Blunt J.W. New nodularins: a general method for structure assignment. Journal of Organic Chemistry. 59:1994;2349-2357.
13. Ohta T., Sueoka E., Iida N., Komori A., Suganuma M., Nishiwaki R., Tatematsu M., Kim S.-J., Carmichael W.W., Fujiki H. Nodularin, a potent inhibitor of protein phosphatases 1 and 2A, is a new environmental carcinogen in male F344 rat liver. Cancer Research. 54:1994;6402-6406.
14. Rinehart K.L., Harada K.-I., Namikoshi M., Chen C., Harvis C.A., Munro M.H.G., Blunt J.W., Mulligan P.E., Beasley V.R., Dahlem A.M., Carmichael W.W. Nodularin, microcystin and the configuration of Adda. Journal of the American Chemical Society. 110:1988;8557-8558.
15. Rippka R., Herdman M. Catalogue of strains. Catalogue and taxonomic handbook. Vol. 1:1992;46 Institut Pasteur, Paris.
16. Sivonen K., Jones G. Cyanobacterial toxins. Chorus I., Bartram J. Toxic cyanobacteria in water. A guide to their public health consequences, monitoring and management. 1999;41-111 E & FN Spon, London.
17. Stanier R.Y., Kunisawa R., Mandel M., Cohen-Bazire G. Purification and properties of unicellular blue-green algae (order Chroococcales). Bacteriological Reviews. 32:1971;171-205.
18. Twist H., Codd G.A. Degradation of the cyanobacterial hepatotoxin, nodularin, under light and dark conditions. FEMS Microbiology Letters. 151:1997;83-88.
19. Ward C.J., Beattie K.A., Lee E.Y.C., Codd G.A. Colorimetric protein phosphatase inhibition assay of laboratory strains and natural blooms of cyanobacteria: comparisons with high-performance liquid chromatographic analysis for microcystins. FEMS Microbiology Letters. 153:1997;465-473.