Degradation of the cyanobacterial hepatotoxin, nodularin, under light and dark conditions

FEMS Microbiology Letters

Volumn 151, Issue 1, 1997, Pages 83-88

  Twist, Hayley ^a   Codd, Geoffrey A ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Cyanobacteria; Hepatotoxin; Nodularia; Nodularin; Toxin

Indexed keywords

NODULARIN;

ARTICLE; CYANOBACTERIUM; LIGHT DARK CYCLE; LIVER TOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STABILITY; TOXIN ANALYSIS;

ANIMALS; ARTEMIA; BACTERIAL TOXINS; CYANOBACTERIA; DARKNESS; DOSE-RESPONSE RELATIONSHIP, RADIATION; DRUG STABILITY; MARINE TOXINS; PEPTIDES, CYCLIC; SUNLIGHT; TIME FACTORS; TOXICITY TESTS; ULTRAVIOLET RAYS;

ARTEMIA SALINA; CYANOBACTERIA; NODULARIA; NODULARIA SPUMIGENA; SALINA;

EID: 0030872048     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(97)00145-6     Document Type: Article

References (21)

1. Codd, G.A., Bell, S.G. and Brooks, W.P. (1989) Cyanobacterial toxins in water. Wat. Sci. Tech. 21, 1-13.
2. Carmichael, W.W. (1992) Cyanobacteria secondary metabolites - the cyanotoxins. J. Appl. Bacteriol. 72, 445-459.
3. Codd, G.A. (1994) Blue-green algal toxins: water-borne hazards to health. In: Water and Public Health (Golding, A.M.B., Noah, N. and Stanwell-Smith, R., Eds.), pp. 271-278. Smith-Gordon, London.
4. Carmichael, W.W. and Falconer, I.R. (1993) Diseases related to freshwater blue-green algal toxins, and control measures. In: Algal Toxins in Seafood and Drinking Water (Falconer, I.E., Ed.), pp. 187-209. Academic Press, London.
5. Bell, S.G. and Codd, G.A. (1994) Cyanobacterial toxins and human health. Rev. Med. Microbiol. 5, 256-264.
6. Francis, G. (1978) Poisonous Australian lake. Nature 18, 11-12.
7. Edler, L., Ferno, S., Lind, M.G., Lundberg, R. and Nilsson, P.O. (1985) Mortality of dogs associated with a bloom of the cyanobacterium Nodularia spumigena in the Baltic Sea. Ophelia 24, 103-109.
8. Carmichael, W.W., Eschedor, J.T., Patterson, G.M.L. and Moore, R.E. (1988) Toxicity and partial structure of hepatotoxic peptide produced by the cyanobacterium Nodularia spumigena Mertens emend. L575 from New Zealand. Appl. Environ. Microbiol. 54, 2257-2263.
9. Harding, W.R., Rowe, N., Wessels, J.C., Beattie, K.A. and Codd, G.A. (1995) Death of a dog attributed to the cyanobacterial (blue-green algal) hepatotoxin, nodularin in South Africa. J. S. Afr. Vet. Assoc. 66, 256-259.
10. Reynolds, C.S. (1987) Cyanobacterial water blooms. In: Advances in Botanical Research, Vol. 13 (Callow, J.A., Ed.), pp. 67-143. Academic Press, London.
11. Richard, D.S., Beattie, K.A. and Codd, G.A. (1983) Toxicity of cyanobacterial blooms from Scottish freshwaters. Environ. Technol. Lett. 4, 377-382.
12. Turner, P.C., Gammie, A.J., Hollinrake, K. and Codd, G.A. (1990) Pneumonia associated with cyanobacteria. Br. Med. J. 300, 833-843.
13. Codd, G.A. (1981) Photoinhibition of photosynthesis and photoinactivation of ribulose-bisphosphate-carboxylase in algae and cyanobacteria. In: Plants and the Daylight Spectrum (Smith, H., Ed.), pp. 315-337. Academic Press, London.
14. Beattie, K.A. (1993) MSc Thesis, University of Dundee.
15. Kotai, J. (1972) Instructions for Preparation of Modified Nutrient Solution Z8 for Algae. Norwegian Institute for Water Research, Oslo.
16. Lawton, L.A., Edwards, C. and Codd, G.A. (1994) Extraction and high-performance liquid chromatographic method for the determination of microcystins in raw and treated waters. Analyst 119, 1525-1530.
17. Campbell, D.L., Lawton, L.A., Beattie, K.A. and Codd, G.A. (1994) Comparative assessment of the specificity of the brine shrimp and Microtox assays to hepatotoxic (microcystin-LR-containing) cyanobacteria. Environ. Toxicol. Wat. Qual. 9, 71-77.
18. Codd, G.A. and Bell, S.G. (1996) The Occurrence and Fate of Blue-Green Algal Toxins in Freshwaters. National Rivers Authority, HMSO, London, 30 pp.
19. Jones, G.J., Bourne, D.G., Blakeley, R.L. and Doelle, H. (1994) Degradation of the cyanobacterial hepatotoxin microcystin by aquatic bacteria. Nat. Toxins 2, 871-876.
20. Tsuji, K., Naito, S., Kondo, F., Ishikawa, N., Watanabe, M.F., Suzuki, M. and Harada, K. (1995) Stability of microcystins from cyanobacteria: effect of light on decomposition and isomerisation. Environ. Sci. Technol. 28, 173-177.
21. Kahru, M., Horstmann, V. and Rud, O. (1994) Satellite detection of cyanobacterial blooms: natural fluctuation or ecosystem change? Ambio 23, 469-472.