1,2,3,4,5,6-Hexahydrobenzo[h][1,6]naphthyridin-5-ones: 5-HT7 receptor affinity

Pharmacy and Pharmacology Communications

Volumn 6, Issue 2, 2000, Pages 67-71

  Hinschberger, A ^a   Gillard, A C ^a   Dauphin, F ^b   Rault, S ^a  

^a UNIVERSITÉ DE CAEN   (France)

^b GIP CYCERON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

NAPHTHYRIDINE DERIVATIVE; SEROTONIN 7 RECEPTOR;

CONFERENCE PAPER; DRUG EFFECT; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; RECEPTOR AFFINITY;

EID: 0034077108     PISSN: 14608081     EISSN: None     Source Type: Journal    
DOI: 10.1211/146080800128735656     Document Type: Conference Paper

References (8)

1. Bureau, I., Chardon, J., Leclaire, A., Hinschberger, A., Rault, S. (1999) Structure of 6-chloro-5H-tetrahydroazepino[3,2-c]-quinoline. Acta Crystallogr. C55:
2. Gillard, A. C., Fabis, F., Jolivet-Fouchet, S., Rault, S. (1997a) Rearrangement of pyrrolo[2,1-c][1,4]benzodiazepines into cyclopenta[b][1,4]benzodiazepines under microwave or conventional heating conditions. Tetrahedron Lett. 38: 2271-2274
3. Gillard, A. C., Fabis, F., Hinschberger, A., Boulouard, M., Jolivet-Fouchet, S., Rault, S. (1997b) Synthesis of new cyclopenta[b][1,4]benzodiazepines and dibenzo[b,f][1,4]diazepines and preliminary pharmacological evaluation. Pharm. Sci. 3: 315-318
4. Hoffman, J. M., Smith, A. M., Rooney, C. S., Fischer, T. E. (1993) Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 4. 3-[2-(Benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one and analogues. J. Med. Chem. 36: 953-966
5. 7 receptor. J. Med. Chem. 42: 533-535
6. Rault, S., Gillard, A. C., Foloppe, M. P., Robba, M. (1995) A new rearrangement under microwave heating conditions: synthesis of cyclopenta[b][1,4]benzodiazepines and tetrahydrodibenzo[b,f][1,4]diazepines. Tetrahedron Lett. 36: 6673-6674
7. Renault, J., Cartron, J. C. (1966) Sur les formes tautomères dans la série des amino-4 quinoléines. C. R. Acad. Sci. Ser. C 262: 1161-1164
8. 7 serotonin receptor subtype. J. Biol. Chem. 268: 18200-18204