메뉴 건너뛰기




Volumn 158, Issue 5, 1997, Pages 2310-2317

Human Mast Cells Activate Fibroblasts: Tryptase is a Fibrogenic Factor Stimulating Collagen Messenger Ribonucleic Acid Synthesis and Fibroblast Chemotaxis

Author keywords

[No Author keywords available]

Indexed keywords

CHYMASE; CHYMASE 2; COLLAGEN; MESSENGER RNA; SERINE PROTEINASE; TRYPTASE;

EID: 0031091747     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (274)

References (73)
  • 1
    • 0029174985 scopus 로고
    • Mast cells: Accessory cells which potentiate fibrosis
    • Gruber, B. L. 1995. Mast cells: accessory cells which potentiate fibrosis. Int. Rev. Immunol. 12:259.
    • (1995) Int. Rev. Immunol. , vol.12 , pp. 259
    • Gruber, B.L.1
  • 2
    • 0028114188 scopus 로고
    • Promotion of mouse fibroblast collagen gene expression by mast cells stimulated via the Fc∈RI: Role for mast cell-derived transforming growth factor-β and tumor necrosis factor-a
    • Gordon, J. R., and S. J. Galli. 1994. Promotion of mouse fibroblast collagen gene expression by mast cells stimulated via the Fc∈RI: role for mast cell-derived transforming growth factor-β and tumor necrosis factor-a. J. Exp. Med. 180: 2027.
    • (1994) J. Exp. Med. , vol.180 , pp. 2027
    • Gordon, J.R.1    Galli, S.J.2
  • 3
    • 0028674019 scopus 로고
    • Tryptase: A mast cell serine protease
    • Schwartz, L. B. 1994. Tryptase: a mast cell serine protease. Methods Enzymol. 244:88.
    • (1994) Methods Enzymol. , vol.244 , pp. 88
    • Schwartz, L.B.1
  • 4
    • 0025864033 scopus 로고
    • Mast cell tryptase is a mitogen for cultured fibroblasts
    • Ruoss, S. J., T. Hartmann, and G. H. Caughey. 1991. Mast cell tryptase is a mitogen for cultured fibroblasts. J. Clin. Invest. 88:493.
    • (1991) J. Clin. Invest. , vol.88 , pp. 493
    • Ruoss, S.J.1    Hartmann, T.2    Caughey, G.H.3
  • 5
    • 0023950976 scopus 로고
    • Establishment of an immature mast cell line from a patient with mast cell leukemia
    • Butterfield, J. H., D. Weiler, G. Dewald, and G. J. Gleich. 1988. Establishment of an immature mast cell line from a patient with mast cell leukemia. Leuk. Res. 12:345.
    • (1988) Leuk. Res. , vol.12 , pp. 345
    • Butterfield, J.H.1    Weiler, D.2    Dewald, G.3    Gleich, G.J.4
  • 6
    • 0028361407 scopus 로고
    • Fate of human keratinocytes during reepithelialization in an organotypic culture model
    • Garlick, J. A., and L. B. Taichman. 1994. Fate of human keratinocytes during reepithelialization in an organotypic culture model. Lab. Invest. 70:916.
    • (1994) Lab. Invest. , vol.70 , pp. 916
    • Garlick, J.A.1    Taichman, L.B.2
  • 7
    • 0027759314 scopus 로고
    • Bis(5-amidino-2-benzimidazolyl)methane and related amidines are potent, reversible inhibitors of mast cell tryptases
    • Caughey, G. H., W. W. Raymond, E. Bacci, R. J. Lombardy, and R. R. Tidwell. 1993. Bis(5-amidino-2-benzimidazolyl)methane and related amidines are potent, reversible inhibitors of mast cell tryptases. J. Pharmacol. Exp. Ther. 264:676.
    • (1993) J. Pharmacol. Exp. Ther. , vol.264 , pp. 676
    • Caughey, G.H.1    Raymond, W.W.2    Bacci, E.3    Lombardy, R.J.4    Tidwell, R.R.5
  • 9
    • 0024474186 scopus 로고
    • Detection of MCt and MCtc types of human mast cells by immunohistochemistry using new monoclonal anti-tryptase and anti-chymase antibodies
    • Irani, A. M., T. R. Bradford, C. L. Kepley, N. M. Schecter, and L. B. Schwartz. 1989. Detection of MCt and MCtc types of human mast cells by immunohistochemistry using new monoclonal anti-tryptase and anti-chymase antibodies. J. Histochem. Cytochem. 37:1509.
    • (1989) J. Histochem. Cytochem. , vol.37 , pp. 1509
    • Irani, A.M.1    Bradford, T.R.2    Kepley, C.L.3    Schecter, N.M.4    Schwartz, L.B.5
  • 11
    • 0016729431 scopus 로고
    • Serial cultivation of strains of human epidermal keratinocytes: The formation of keratinocyte colonies from single cells
    • Rhinewald, J. G., and H. Green. 1975. Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinocyte colonies from single cells. Cell 6:331.
    • (1975) Cell , vol.6 , pp. 331
    • Rhinewald, J.G.1    Green, H.2
  • 12
    • 0025998184 scopus 로고
    • Fibrohlast chemotaxis induction by human recombinant interleukin-4: Identification by synthetic peptide analysis of two chemotactic domains residing in amino acid sequences 70-88 and 89-122
    • Postlethwaite, A. E., and J. M. Seyer. 1991. Fibrohlast chemotaxis induction by human recombinant interleukin-4: identification by synthetic peptide analysis of two chemotactic domains residing in amino acid sequences 70-88 and 89-122. J. Clin. Invest. 87:2147.
    • (1991) J. Clin. Invest. , vol.87 , pp. 2147
    • Postlethwaite, A.E.1    Seyer, J.M.2
  • 13
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156.
    • (1987) Anal. Biochem. , vol.162 , pp. 156
    • Chomczynski, P.1    Sacchi, N.2
  • 14
    • 0025201144 scopus 로고
    • A simple and fast method to extract RNA from tissue culture cells
    • Peppel, K., and C. Baglioni. 1990. A simple and fast method to extract RNA from tissue culture cells. Biotechniques 9:711.
    • (1990) Biotechniques , vol.9 , pp. 711
    • Peppel, K.1    Baglioni, C.2
  • 16
    • 0020480644 scopus 로고
    • Cloning and characterization of five overlapping cDNAs specific for the human pro a1(I) collagen chain
    • Chu, M. L., J. C. Myers, M. P. Bernard, J. F. Ding, and F. Ramirez. 1982. Cloning and characterization of five overlapping cDNAs specific for the human pro a1(I) collagen chain. Nucleic Acids Res. 10:5925.
    • (1982) Nucleic Acids Res. , vol.10 , pp. 5925
    • Chu, M.L.1    Myers, J.C.2    Bernard, M.P.3    Ding, J.F.4    Ramirez, F.5
  • 17
    • 0027501673 scopus 로고
    • Detecting of messenger RNA by in situ hybridization
    • Sassoon, D., and N. Rosenthal. 1993. Detecting of messenger RNA by in situ hybridization. Methods Enzymol. 225:384.
    • (1993) Methods Enzymol. , vol.225 , pp. 384
    • Sassoon, D.1    Rosenthal, N.2
  • 19
    • 0022969842 scopus 로고
    • 2+ ionophore A23187 in cultured human fibroblasts
    • 2+ ionophore A23187 in cultured human fibroblasts. J. Biol. Chem. 261: 12060.
    • (1986) J. Biol. Chem. , vol.261 , pp. 12060
    • Flaherty, M.1    Chojkier, M.2
  • 21
    • 0021907874 scopus 로고
    • Increased dermal masi cell populations in progressive systemic sclerosis: A link in chronic fibrosis?
    • Hawkins, R. A., H. N. Claman, R. A. F. Clark, and J. C. Steigerwald. 1985. Increased dermal masi cell populations in progressive systemic sclerosis: a link in chronic fibrosis? Ann. Intern. Med. 102:182.
    • (1985) Ann. Intern. Med. , vol.102 , pp. 182
    • Hawkins, R.A.1    Claman, H.N.2    Clark, R.A.F.3    Steigerwald, J.C.4
  • 22
    • 0024364169 scopus 로고
    • Increased number of mast cells accompany enhanced collagen synthesis in linear localized scleroderma
    • Takeda, K., A. Hatamochi, and H. Ueki. 1989. Increased number of mast cells accompany enhanced collagen synthesis in linear localized scleroderma. Arch. Dermatol. Res. 281:288.
    • (1989) Arch. Dermatol. Res. , vol.281 , pp. 288
    • Takeda, K.1    Hatamochi, A.2    Ueki, H.3
  • 23
    • 0025050886 scopus 로고
    • Myocardial mast cells in systemic sclerosis: A report of three fatal cases
    • Lichtbroun, A. S., L. M. Sandhaus, R. C. Giorno, H. Kim, and J. R. Seibold. 1990. Myocardial mast cells in systemic sclerosis: a report of three fatal cases. Am. J. Med. 89:372.
    • (1990) Am. J. Med. , vol.89 , pp. 372
    • Lichtbroun, A.S.1    Sandhaus, L.M.2    Giorno, R.C.3    Kim, H.4    Seibold, J.R.5
  • 24
    • 0018358936 scopus 로고
    • Ultrastructure of pulmonary mast cells in patients with fibrotic lung disorders
    • Kawanami, O., V. J. Ferrans, J. D. Fulmer, and R. G. Crystal. 1979. Ultrastructure of pulmonary mast cells in patients with fibrotic lung disorders. Lab. Invest. 40:717.
    • (1979) Lab. Invest. , vol.40 , pp. 717
    • Kawanami, O.1    Ferrans, V.J.2    Fulmer, J.D.3    Crystal, R.G.4
  • 27
    • 0014465256 scopus 로고
    • Mast cells in areas of experimental bone resorption and remodelling
    • Severson, A. R. 1969. Mast cells in areas of experimental bone resorption and remodelling. Br. J. Exp. Pathol. 50:17.
    • (1969) Br. J. Exp. Pathol. , vol.50 , pp. 17
    • Severson, A.R.1
  • 28
    • 0025738901 scopus 로고
    • Mast cell tryptase and histamine concentrations in bronchoalveolar lavage fluid from patients with interstitial lung disease
    • Walls, A. F., A. R. Bennett, R. C. Godfrey, S. T. Holgate, and M. K. Church. 1991. Mast cell tryptase and histamine concentrations in bronchoalveolar lavage fluid from patients with interstitial lung disease. Clin. Sci. 81:183.
    • (1991) Clin. Sci. , vol.81 , pp. 183
    • Walls, A.F.1    Bennett, A.R.2    Godfrey, R.C.3    Holgate, S.T.4    Church, M.K.5
  • 29
    • 0026680865 scopus 로고
    • The relationship of mast cells and their secreted products Io the volume of fibrosis in posttransplant hearts
    • Li, Q. Y., A. Razaahmad, M. A. Macaulay, L. D. Lalonde, G. Rowden, E. Trethewey, and S. Dean. 1992. The relationship of mast cells and their secreted products Io the volume of fibrosis in posttransplant hearts. Transplantation 53: 1047.
    • (1992) Transplantation , vol.53 , pp. 1047
    • Li, Q.Y.1    Razaahmad, A.2    Macaulay, M.A.3    Lalonde, L.D.4    Rowden, G.5    Trethewey, E.6    Dean, S.7
  • 30
    • 0021804366 scopus 로고
    • Bone marrow findings in systemic mastocytosis
    • Horny, H., M. R. Parwaresch, and K. Lennert. 1985. Bone marrow findings in systemic mastocytosis. Hum. Pathol. 16:808.
    • (1985) Hum. Pathol. , vol.16 , pp. 808
    • Horny, H.1    Parwaresch, M.R.2    Lennert, K.3
  • 32
    • 0028181253 scopus 로고
    • Transforming growth factor-β1 mediates chemotaxis of mast cells
    • Gruber, B. L., M. J. Myrchese, and R. Kew. 1994. Transforming growth factor-β1 mediates chemotaxis of mast cells. J. Immunol. 152:5860.
    • (1994) J. Immunol. , vol.152 , pp. 5860
    • Gruber, B.L.1    Myrchese, M.J.2    Kew, R.3
  • 33
    • 0029166407 scopus 로고
    • Angiogenic factors stimulate masl cell migration
    • Gruber, B. L., M. J. Marchese, and R. R. Kew. 1995. Angiogenic factors stimulate masl cell migration. Blood 86:2488.
    • (1995) Blood , vol.86 , pp. 2488
    • Gruber, B.L.1    Marchese, M.J.2    Kew, R.R.3
  • 36
    • 0017143956 scopus 로고
    • Mast cell activation and tissue cell proliferation
    • Norrby, K., L. Enerbäck, and L. Franzén. 1976. Mast cell activation and tissue cell proliferation. Cell Tissue Res. 170:289.
    • (1976) Cell Tissue Res. , vol.170 , pp. 289
    • Norrby, K.1    Enerbäck, L.2    Franzén, L.3
  • 37
    • 0019777230 scopus 로고
    • On the 48/80-induced secretion of tissue mast cells and its mitogenic effect on nearby cells in the intact rat
    • Norrby, K. 1981. On the 48/80-induced secretion of tissue mast cells and its mitogenic effect on nearby cells in the intact rat. Virchows Arch. B Cell Pathol. 38:57.
    • (1981) Virchows Arch. B Cell Pathol. , vol.38 , pp. 57
    • Norrby, K.1
  • 38
    • 0020662955 scopus 로고
    • Intradermal mast-cell secretion causing cutaneous mitogenesis
    • Norrby, K. 1983. Intradermal mast-cell secretion causing cutaneous mitogenesis. Virchows Arch. B Cell Pathol. 42:263.
    • (1983) Virchows Arch. B Cell Pathol. , vol.42 , pp. 263
    • Norrby, K.1
  • 40
  • 42
    • 0023178492 scopus 로고
    • Inhibition of fibrosis in Tsk mice by blocking mast cell degranulation
    • Walker, M. A., R. A. Harley, and E. C. LeRoy. 1987. Inhibition of fibrosis in Tsk mice by blocking mast cell degranulation. J. Rheumatol. 14:299.
    • (1987) J. Rheumatol. , vol.14 , pp. 299
    • Walker, M.A.1    Harley, R.A.2    LeRoy, E.C.3
  • 43
    • 0025056551 scopus 로고
    • Ketotifen prevents skin fibrosis in the TSK/+ mouse
    • Walker, M., R. Harley, and E. C. LeRoy. 1990. Ketotifen prevents skin fibrosis in the TSK/+ mouse. J. Rheumatol. 17:57.
    • (1990) J. Rheumatol. , vol.17 , pp. 57
    • Walker, M.1    Harley, R.2    LeRoy, E.C.3
  • 45
    • 0021829550 scopus 로고
    • Chronic graft-versus-host disease (GVHD) as a model for scleroderma. II. Mast cell depletion with deposition of immunoglohulins in the skin and fibrosis
    • Claman, H. N., B. D. Jaffee, J. C. Huff, and R. A. F. Clark. 1985. Chronic graft-versus-host disease (GVHD) as a model for scleroderma. II. Mast cell depletion with deposition of immunoglohulins in the skin and fibrosis. Cell. Immunol. 94:73.
    • (1985) Cell. Immunol. , vol.94 , pp. 73
    • Claman, H.N.1    Jaffee, B.D.2    Huff, J.C.3    Clark, R.A.F.4
  • 46
    • 0022448058 scopus 로고
    • Mast cell "disappearance" in chronic murine graft-vs-host disease (GVHD): Ultrastructural demonstration of "phantom mast cells."
    • Claman, H. N., K. Lee Choi, W. Sujansky, and A. E. Valter. 1986. Mast cell "disappearance" in chronic murine graft-vs-host disease (GVHD): ultrastructural demonstration of "phantom mast cells." J. Immunol. 137:2009.
    • (1986) J. Immunol. , vol.137 , pp. 2009
    • Claman, H.N.1    Lee Choi, K.2    Sujansky, W.3    Valter, A.E.4
  • 47
    • 0024553804 scopus 로고
    • Mast cell changes in a case of rapidly progressive scleroderma: Ultrastructural analysis
    • Claman, H. N. 1989. Mast cell changes in a case of rapidly progressive scleroderma: ultrastructural analysis. J. Invest. Dermatol. 92:290.
    • (1989) J. Invest. Dermatol. , vol.92 , pp. 290
    • Claman, H.N.1
  • 48
    • 0025633516 scopus 로고
    • Dermal mast cell degranulation in systemic sclerosis
    • Seibold, J. R., R. C. Giorno, and H. N. Claman. 1990. Dermal mast cell degranulation in systemic sclerosis. Arthritis Rheum. 33:1702.
    • (1990) Arthritis Rheum. , vol.33 , pp. 1702
    • Seibold, J.R.1    Giorno, R.C.2    Claman, H.N.3
  • 49
  • 50
    • 0025216059 scopus 로고
    • Mast cells enhance migration and proliferation of fibroblasts into an in vitro wound
    • Levi-Schaeffer, F., and A. Kupietzky. 1990. Mast cells enhance migration and proliferation of fibroblasts into an in vitro wound. Exp. Cell Res. 188:42.
    • (1990) Exp. Cell Res. , vol.188 , pp. 42
    • Levi-Schaeffer, F.1    Kupietzky, A.2
  • 51
    • 0024382157 scopus 로고
    • Structural alterations in fibroblast monolayers caused by must cell degranulation
    • Ginsburg, H., M. Amira, J. Padawer, and S. Davidson. 1989. Structural alterations in fibroblast monolayers caused by must cell degranulation. J. Leukocyte Biol. 45:491.
    • (1989) J. Leukocyte Biol. , vol.45 , pp. 491
    • Ginsburg, H.1    Amira, M.2    Padawer, J.3    Davidson, S.4
  • 52
    • 0242393804 scopus 로고
    • Co-culture of interleukin 3-dependent mouse mast cells with fibroblasts results in a phenotypic change of the mast cells
    • Levi-Schaffer, F., K. F. Austen, P. M. Gravallese, and R. L. Stevens. 1986. Co-culture of interleukin 3-dependent mouse mast cells with fibroblasts results in a phenotypic change of the mast cells. Proc. Natl. Acad. Sci. USA 83:6485.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 6485
    • Levi-Schaffer, F.1    Austen, K.F.2    Gravallese, P.M.3    Stevens, R.L.4
  • 53
    • 0024521303 scopus 로고
    • In vitro regeneration of activated rat peritoneal mast cells cocultured with 3T3 fibroblasts
    • Levi-Schaffer, F., and N. Riesel. 1989. In vitro regeneration of activated rat peritoneal mast cells cocultured with 3T3 fibroblasts. Cell. Immunol. 119:30.
    • (1989) Cell. Immunol. , vol.119 , pp. 30
    • Levi-Schaffer, F.1    Riesel, N.2
  • 55
    • 0023686432 scopus 로고
    • Interaction between mast cells and perineural fibroblasts in neurofibroma: New insights into mast cell function
    • Kirkpatrick, C. J., and A. Curry. 1988. Interaction between mast cells and perineural fibroblasts in neurofibroma: new insights into mast cell function. Pathol. Res. Pract. 183:453.
    • (1988) Pathol. Res. Pract. , vol.183 , pp. 453
    • Kirkpatrick, C.J.1    Curry, A.2
  • 56
    • 0028363863 scopus 로고
    • Tryptase: A clinical indicator of mast cell-dependent events
    • Schwartz, L. B. 1994. Tryptase: a clinical indicator of mast cell-dependent events. Allergy Proc. 15:119.
    • (1994) Allergy Proc. , vol.15 , pp. 119
    • Schwartz, L.B.1
  • 57
    • 0019888627 scopus 로고
    • Tryptase from human pulmonary mast cells: Purification and characterization
    • Schwartz, L. B., R. A. Lewis, and K. F. Austen. 1981. Tryptase from human pulmonary mast cells: purification and characterization. J. Biol. Chem. 256:11939.
    • (1981) J. Biol. Chem. , vol.256 , pp. 11939
    • Schwartz, L.B.1    Lewis, R.A.2    Austen, K.F.3
  • 58
    • 0022872843 scopus 로고
    • Regulation of tryptase from human lung mast cells by heparin: Stabilization of the active tetramer
    • Schwartz, L. B., and T. R. Bradford. 1986. Regulation of tryptase from human lung mast cells by heparin: stabilization of the active tetramer. J. Biol. Chem. 261:7372.
    • (1986) J. Biol. Chem. , vol.261 , pp. 7372
    • Schwartz, L.B.1    Bradford, T.R.2
  • 59
    • 0019471330 scopus 로고
    • Acid hydrolases and tryptase from secretory granules of dispersed human lung mast cells
    • Schwartz, L. B., R. A. Lewis, D. Seldin, and K. Austen. 1981. Acid hydrolases and tryptase from secretory granules of dispersed human lung mast cells. J. Immunol. 126:1290.
    • (1981) J. Immunol. , vol.126 , pp. 1290
    • Schwartz, L.B.1    Lewis, R.A.2    Seldin, D.3    Austen, K.4
  • 60
    • 0025217194 scopus 로고
    • Immunologic and physicochemical evidence for conformational changes occurring on conversion of human mast cell tryptase from active tetramer to inactive monomer: Production of monoclonal antibodies recognizing active tryptase
    • Schwartz, L. B., T. R. Bradford, D. C. Lee, and J. F. Chlebowski. 1990. Immunologic and physicochemical evidence for conformational changes occurring on conversion of human mast cell tryptase from active tetramer to inactive monomer: production of monoclonal antibodies recognizing active tryptase. J. Immunol. 144:2304.
    • (1990) J. Immunol. , vol.144 , pp. 2304
    • Schwartz, L.B.1    Bradford, T.R.2    Lee, D.C.3    Chlebowski, J.F.4
  • 61
    • 0024434198 scopus 로고
    • Cloning and characterization of complementary DNA for human tryptase
    • Miller, J. S., E. H. Westin, and L. B. Schwartz. 1989. Cloning and characterization of complementary DNA for human tryptase. J. Clin. Invest. 84: 1188.
    • (1989) J. Clin. Invest. , vol.84 , pp. 1188
    • Miller, J.S.1    Westin, E.H.2    Schwartz, L.B.3
  • 62
    • 0024429920 scopus 로고
    • Synovial procollagenase activation by human mast cell tryptase dependence upon matrix metalloproteinase 3 activation
    • Gruber, B. L., M. J. Marchese, K. Suzuki, L. B. Schwartz, Y. Okada, H. Nagase, and N. S. Ramamurthy. 1989. Synovial procollagenase activation by human mast cell tryptase dependence upon matrix metalloproteinase 3 activation. J. Clin. Invest. 84:1657.
    • (1989) J. Clin. Invest. , vol.84 , pp. 1657
    • Gruber, B.L.1    Marchese, M.J.2    Suzuki, K.3    Schwartz, L.B.4    Okada, Y.5    Nagase, H.6    Ramamurthy, N.S.7
  • 64
    • 0028363122 scopus 로고
    • Human mast cell tryptase activates single-chain urinary-type plasminogen activator (pro-urokinase)
    • Stack, M. S., and D. A. Johnson. 1994. Human mast cell tryptase activates single-chain urinary-type plasminogen activator (pro-urokinase). J. Biol. Chem. 269: 9416.
    • (1994) J. Biol. Chem. , vol.269 , pp. 9416
    • Stack, M.S.1    Johnson, D.A.2
  • 65
    • 0022388692 scopus 로고
    • The fibrinogenolytic activity of purified tryptase from human lung mast cells
    • Schwartz, L. B., T. R. Bradford, B. H. Littman, and B. U. Wintroub. 1985. The fibrinogenolytic activity of purified tryptase from human lung mast cells. J. Immunol. 135:2762.
    • (1985) J. Immunol. , vol.135 , pp. 2762
    • Schwartz, L.B.1    Bradford, T.R.2    Littman, B.H.3    Wintroub, B.U.4
  • 66
    • 0027240447 scopus 로고
    • Catabolism of intact type VI collagen microfibrils: Susceptibility to degradation by serine proteases
    • Kielty, C. M., M. Lees, C. A. Shuttleworth, and D. Wooley. 1993. Catabolism of intact type VI collagen microfibrils: susceptibility to degradation by serine proteases. Biochem. Biophys. Res. Commun. 191:1230.
    • (1993) Biochem. Biophys. Res. Commun. , vol.191 , pp. 1230
    • Kielty, C.M.1    Lees, M.2    Shuttleworth, C.A.3    Wooley, D.4
  • 68
    • 0027960284 scopus 로고
    • Molecular mechanisms of thrombin signaling
    • Coughlin, S. R. 1994. Molecular mechanisms of thrombin signaling. Semin. Hematol. 31:270.
    • (1994) Semin. Hematol. , vol.31 , pp. 270
    • Coughlin, S.R.1
  • 69
    • 0026771255 scopus 로고
    • Human tryptase as a potent, cell-specific mitogen: Role of signaling pathways in synergistic responses
    • Hartmann, T., S. J. Ruoss, W. W. Raymond, K. Seuwen, and G. H. Caughey. 1992. Human tryptase as a potent, cell-specific mitogen: role of signaling pathways in synergistic responses. Am. J. Physiol. 262:L528.
    • (1992) Am. J. Physiol. , vol.262
    • Hartmann, T.1    Ruoss, S.J.2    Raymond, W.W.3    Seuwen, K.4    Caughey, G.H.5
  • 70
    • 0030032558 scopus 로고    scopus 로고
    • Mast cell tryptase is a mitogen for epithelial cells: Stimulation of IL-8 production and intercellular adhesion molecule-1 expression
    • Cairns, J. A., and A. F. Walls. 1996. Mast cell tryptase is a mitogen for epithelial cells: stimulation of IL-8 production and intercellular adhesion molecule-1 expression. J. Immunol. 156:275.
    • (1996) J. Immunol. , vol.156 , pp. 275
    • Cairns, J.A.1    Walls, A.F.2
  • 71
    • 0028031390 scopus 로고
    • Modulation of thrombin and thrombin receptor peptide mitogenicity by human lung mast cell tryptase
    • Hartmann, T., S. J. Ruoss, and G. H. Caughey. 1994. Modulation of thrombin and thrombin receptor peptide mitogenicity by human lung mast cell tryptase. Am. J. Physiol. 267:1113.
    • (1994) Am. J. Physiol. , vol.267 , pp. 1113
    • Hartmann, T.1    Ruoss, S.J.2    Caughey, G.H.3
  • 73


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.