Mechanisms and sites of pyrogenic action exerted by staphylococcal enterotoxin A in rabbits

Neuroscience Letters

Volumn 236, Issue 1, 1997, Pages 53-56

  Huang, W T ^a   Lin, M T ^b   Won, S J ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Cyclo oxygenase; Fever; Nitric oxide synthase; Organum vasculosum laminae terminalis

Indexed keywords

AMINOGUANIDINE; ANISOMYCIN; DEXAMETHASONE; DICLOFENAC; INDOMETACIN; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; PROTEIN SYNTHESIS INHIBITOR; STAPHYLOCOCCUS ENTEROTOXIN A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; BRAIN THIRD VENTRICLE; CONTROLLED STUDY; FEVER; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT;

ANIMALS; ANISOMYCIN; CYCLOOXYGENASE INHIBITORS; DEXAMETHASONE; DICLOFENAC; ENTEROTOXINS; ENZYME INHIBITORS; GUANIDINES; INDOMETHACIN; INJECTIONS, INTRAVENTRICULAR; MALE; NITRIC OXIDE SYNTHASE; PROTEIN SYNTHESIS INHIBITORS; PYROGENS; RABBITS; STAPHYLOCOCCUS AUREUS; SUPERANTIGENS;

EID: 0031585497     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(97)00759-3     Document Type: Article

References (24)

1. Alouf, J.E., Knoll, H. and Kohler, W., The family of mitogenic, shock-inducing and superantigenic toxins from staphylococci and streptococci. In J.E. Alouf and J.H. Freer (Eds.), Sourcebook of Bacterial Protein Toxins, Academic Press, San Diego, CA, 1991, pp. 367-414.
2. Blatteis C.M., Bealer S.L., Hunter W.S., Llanos Q.J., Ahokas R.A., Mashburn T.A. Jr. Suppression of fever after lesions of the anteroventral third ventricle in guinea pigs. Brain Res. Bull. 11:1983;519-526.
3. Clark W.G., Page J.S. Pyrogenic responses to staphylococcal enterotoxins A and B in cats. J. Bacteriol. 96:1968;1940-1946.
4. Hashimoto M., Ueno T., Iriki M. What roles does the organum vasculosum laminae terminalis play in fever in rabbits? Pflügers Arch. Eur. J. Physiol. 429:1994;50-57.
5. Hodoval L.F., Morris E.L., Crawley G.J., Beisel W.R. Pathogenesis of lethal shock after intravenous staphylococcal enterotoxin B in monkeys. Appl. Microbiol. 16:1968;187-192.
6. Huang W.T., Lin M.T., Won S.J. Staphylococcal enterotoxin A-induced fever is associated with increased circulating levels of cytokines in rabbits. Infect. Immun. 65:1997;2656-2662.
7. Knowles R.G., Salter M., Brooks S.L., Moncada S. Antiinflammatory glucocorticoids inhibit the induction by endotoxin of nitric oxide synthase in the lung, liver and aorta of the rat. Biochem. Biophys. Res. Commun. 172:1990;1042-1048.
8. Lin J.H., Lin M.T. Nitric oxide synthase-cyclooxygenase pathways in organum vasculosum laminae terminalis may mediate pyrogenic fever in rabbits. Br. J. Pharmacol. 118:1996;179-185.
9. Lin J.H., Lin M.T. Inhibition of nitric oxide synthase or cyclo-oxygenase pathways in organum vasculosum laminae terminalis attenuates interleukin-1β fever in rabbits. Neurosci. Lett. 208:1996;155-158.
10. Lin M.T., Lin J.H., Yang Y.L. Dexamethasone administrated into organum vasculosum laminae terminalis of rabbits induced antipyresis via inhibiting nitric oxide pathway in situ. Neurosci. Lett. 230:1997;53-56.
11. Marrack P., Kappler J. The staphylococcal enterotoxins and their relatives. Science. 248:1990;705-711.
12. 2 sensitivity of the organum vasculosum laminae terminalis region and preoptic area in rat brain slices. J. Physiol. 454:1992;197-212.
13. 1 as a modulator for temperature regulation in the central nervous system of the cat (abstract). J. Physiol. 207:1970;76P-77P.
14. Misko T.P., Moore W.M., Kasten T.P., Nickols G.A., Corbett J.A., Tilton R.G., McDaniel M.L., Williamson J.R., Currie M.G. Selective inhibition of the inducible nitric oxide synthase by aminoguanidine. Eur. J. Pharmacol. 233:1993;119-125.
15. Mitchell J.A., Akarasereenont P., Thiemermann C., Flower R.J., Vane J.R. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclo-oxygenase. Proc. Natl. Acad. Sci. USA. 90:1993;11693-11697.
16. Morimoto A., Murakami N., Nakamori T., Watanabe T. Evidence for separate mechanisms of induction of biphasic fever inside and outside the blood-brain barrier in rabbits. J. Physiol. 383:1987;629-637.
17. Sawyer G.H., Everett J.W., Green J.D. The rabbit diencephalon in stereotaxic coordinates. J. Comp. Neurol. 101:1954;801-824.
18. Spero, L., Johnson-Winergar, A. and Schmidt, J.J., Enterotoxins of staphylococci. In M.C. Hardegree and A.T. Tu (Eds.), Handbook of Natural Toxin, Marcel Dekker, New York, 1988, pp. 131-163.
19. Stitt J.T. Evidence for the involvement of the organum vasculosum laminae terminalis in the febrile response of rabbits and rats. J. Physiol. 368:1985;501-511.
20. 1 within the hypothalamus of the rat. J. Physiol. (Lond.). 432:1991;99-110.
21. Szabo C., Thiemermann C., Wu C.C., Perretti M., Vane J.R. Attenuation of the induction of nitric oxide synthase by endogenous glucocorticoids accounts for endotoxin tolerance in vivo. Proc. Natl. Acad. Sci. USA. 91:1994;271-275.
22. Veale, W.L. and Cooper, K.E., Evidence for the involvement of prostaglandin in fever. In K. Lederis and W. Veale (Eds.), Recent Studies of Hypothalamic Function, Karger, Basel, 1974, pp. 359-370.
23. Watkins L.R., Goehler L.E., Relton J.K., Tartaglia N., Silbert L., Martin D., Maier S.F. Blockade of interleukin-1 induced hyperthermia by subdiaphragmatic vagotomy: evidence for vagal mediation of immune-brain communication. Neurosci. Lett. 183:1995;27-31.
24. Wu C.C., Croxtall J.D., Perretti M., Bryant C.E., Thiemermann C., Flower R.J., Vane J.R. Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat. Proc. Natl. Acad. Sci. USA. 92:1995;3473-3477.