Suppressive effects of the Chinese herbal remedy Tripterygium wilfordii Hook f on eosinophilia and IgE hyperproduction in mice

Allergology International

Volumn 49, Issue 1, 2000, Pages 37-45

  Asano, Kazuhito ^a   Sugimoto, Kayo ^a   Watanabe, Tomiko ^a   Hisano, Masataka ^a   Hisamitsu, Tadashi ^a  

^a SHOWA UNIVERSITY   (Japan)

Author keywords

Eosinophilia; Immunoglobulin E; Mesocestoides cortii; Mouse; Suppression; Tripterygium wilfordii

Indexed keywords

CD40 ANTIGEN; CD86 ANTIGEN; IMMUNOGLOBULIN E; INTERLEUKIN 4; INTERLEUKIN 5; TRIPTERYGIUM WILFORDII EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; CYTOKINE PRODUCTION; DRUG MECHANISM; EOSINOPHILIA; IMMUNOGLOBULIN BLOOD LEVEL; MALE; MOUSE; NONHUMAN; PARASITOSIS; PRIORITY JOURNAL;

EID: 0034071652     PISSN: 13238930     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1592.2000.00156.x     Document Type: Article

References (41)

1. Snapper JR. Inflammation and airway functions: The asthma syndrome. Am. Rev. Respir. Dis. 1990; 141: 531-3.
2. Konno S, Asano K, Kurokawa M et al. Antiasthmatic activity of a macrolide antibiotic, roxithromycin: Analysis of possible mechanisms in vitro and in vivo. Int. Arch. Allergy Immunol. 1994; 105: 308-16.
3. Konno S, Asano K, Gonokami Y et al. Effects of azelastine on endotoxin-induced airway hyperresponsiveness in mice. Int. Arch. Allergy Immunol. 1995; 108: 292-7.
4. Konno S, Asano K, Okamoto K et al. Inhibition of cytokine production from human peripheral blood leukocytes by anti-allergic agents in vitro. Eur. J. Pharmacol. 1994; 264: 265-8.
5. Konno S, Adachi M, Asano K et al. Suppressive effects of IPD-1151T (suplatast-tosilate) on induction of mast cells from normal splenocytes. Eur. J. Pharmacol. 1994; 259: 15-20.
6. Bissonette EY, Enciso JA, Befus AD. Inhibition of tumor necrosis factor-alpha (TNF-α) release from mast cells by the anti-inflammatory drugs, sodium cromoglycate and nedocromil sodium. Clin. Exp. Immunol. 1995; 102: 78-84.
7. Bonham CA, Thomson AW. Anti-inflammatory agents in allergic disease. Clin. Exp. Immunol. 1995; 102: 1-5.
8. Bieber T. Topical tacrolimus (FK 506): A new milestone in the management of atopic dermatitis. J. Allergy Clin. Immunol. 1998; 102: 555-7.
9. Jia L. Chemistry and pharmacology and clinical application of the plants of Tripterygium family. Yao. Xue. Tong. Bao. 1985; 20: 101-5.
10. Wenyan X, Jiarun Z, Xueyu L. Tripterygium in dermatologic therapy. Int. J. Dermatol. 1985; 24: 152-7.
11. Guan F, Wang DH. Observation of therapeutic effect of Tripterygium wilfordii in psoriasis. J. Clin. Dermatol. 1981; 10: 91-3.
12. Yang SX, Xie SS, Gao HL, Ma DL, Long ZZ. Triptolide suppresses T-lymphocyte proliferation by inhibiting interleukin-2 receptor expression, but spares interleukin-2 production and mRNA expression. Int. J. Immunopharmacol. 1994; 16: 895-904.
13. Yang SX, Gao HL, Xie SS, Zhang WR, Long ZZ. Immunosuppression of Triptolide and its effect on skin allograft survival. Int. J. Immunopharmacol. 1992; 14: 963-9.
14. Tao X, Cai JJ, Lipsky PE. The identity of immunosuppressive components of the ethyl acetate extract and chloroform methanol extract (T2) of Tripterygium wilfordii Hook f. J. Pharmacol. Exp. Therapeutics 1995; 272: 1305-12.
15. Asano K, Matsuishi J, Yu Y et al. Suppressive activity of the chloroform extract of Tripterygium wilfordii Hook f on effector T cell activation during Hymenolepis nana infection in mice. Am. J. Chin. Med. 1998; 26: 181-9.
16. Zhang XQ, Lai CY, Zhang ZH. Effect of Tripterygium wilfordii Hook f on T lymphocyte subsets in children with asthma. Acad. J. First Med. College PLA 1989; 9: 102-5.
17. Master S, Barrett-Conner E. Parasite and asthma-Predictive or protective? Epidemiol. Rev. 1980; 7: 49-58.
18. Moqbel R, Pritchard DI. Parasite and allergy: Evidence for a cause and effect relationship. Clin. Exp. Allergy 1990; 20: 611-18.
19. Dold S, Heinrich J, Wichmann EH, Wjst M. Ascaris-specific IgE and allergic sensitization in a cohort of school children in the former East Germany. J. Allergy Clin, Immunol. 1998; 102: 414-20.
20. Nishida M, Yamada M, Uchikawa R et al. Ketotifen, an antiallergic agent, suppresses pulmonary eosinophilia induced by the nematoda Nippostrongylus brasiliensis in rats. Jpn. J. Trop. Med. Hyg. 1997; 25: 107-12.
21. Watanabe N. Suppressive effect of terfenadine on eosinophilia and anaphylactic reaction. Prog. Med. 1998; 18: 93-7.
22. Niwa A, Miyazato T. Reactive oxygen intermediates from eosinophils in mice infected with Hymenolepis nana. Parasite Immunol. 1996; 18: 285-95.
23. Kay AB. T lymphocytes and their products in atopic allergy and asthma. Int. Arch. Allergy Appl. Immunol. 1991; 94: 189-93.
24. Yamaguchi Y, Suda T, Suda J et al. Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors. J. Exp. Med. 1988; 167: 1737-42.
25. Nakazawa M, Fang JQ, Asano K et al. Influence of Tripterygium wilfordii Hook f, a Chinese traditional herb, on macrophage function in mice. II. Inhibition of inflammatory mediator production in vivo. Showa University J. Med. Sci. 1998; 10: 179-85.
26. Asano K, Yu Y, Kasahara T, Hisamitsu T. Inhibition of murine chronic graft-versus-host disease by the chloroform extract of Tripterygium wilfordii Hook f. Transplant. Immunol. 1997; 5: 315-19.
27. Doutrelepont JM, Moser M, Leo O, Abramowicz D, Vanderhaegen ML. Hyper IgE in stimulatory graft-versus-host disease: Role of IL- 4. Clin. Exp. Immunol. 1991; 83: 133-6.
28. Bundick RV, Crass RI, Holness E. The effect of cyclosporin A, FK-506, and rapamycin on the murine chronic graft-versus-host response-An in vivo model of Th2-like activity. Clin. Exp. Immunol. 1995; 99: 467-72.
29. Moqbel R, Levi-Schaffer F, Kay AB. Cytokine generation by eosinophils. J. Allergy Clin. Immunol. 1994; 94: 1183-8.
30. Corrigan CJ, Kay AB. T cells and eosinophils in the pathogenesis of asthma, Immunol. Today 1992; 13: 501-6.
31. Kay AB. Asthma and inflammation. J. Allergy Clin. Immunol. 1991; 87: 893-910.
32. Zhang LX, Gu KX, Cao ZF, Pan DJ, Zhang WJ. Effect of Tripterygium wilfordii Hook f on some immune functions. Shanghai J. Immunol. 1986; 6: 277-9.
33. Zuo DM, Zhang SL. Effect of Tripterygium wilfordii Hook f in the northeast of China on antibody production in mice. J. Norman Bethune University Med. Sci. 1986; 12: 397-9.
34. Lenshow DJ, Walunas TL, Bluestone JA. CD28/B7 system of T cell costimulation. Annu. Rev. Immunol. 1996; 14: 233-58.
35. Tsuyuki S, Tsuyuki J, Einsle K, Kopf M, Coyle AJ. Costimulation through B7-2 (CD86) is required for the induction of a lung mucosal T helper cell 2 (Th2) immune response and altered airway responsiveness. J. Exp. Med. 1997; 185: 1671-9.
36. Jirapongsananuruk O, Hofer M, Trumble AE, Norris DA, Leung DYM. Enhanced expression of B7.2 (CD86) in patients with atopic dermatitis: A potential role in the modulation of IgE synthesis. J. Immunol. 1998; 160: 4622-7.
37. Neerven RJJ, De Pol MM, Der Zee JS, Stiekema FEM, Boer M, Kapsenberg ML. Requirement of CD28-CD86 costimulation for allergen-specific T cell proliferation and cytokine expression. Clin. Exp. Allergy 1998; 28: 808-16.
38. Worm M, Henz BM. Molecular regulation of human IgE synthesis. J. Mol. Med. 1997; 75: 440-7.
39. Zhang LX, Yu FK, Zhang QY, Fang Z, Pan DJ. Immunosuppressive and anti-inflammatory activities of tripterine. Acta Pharm. Sinica 1990; 25: 573-7.
40. Zheng JR, Fang JL, Gu KX et al. Screening of active anti-inflammatory immunosuppressive and antifertile compounds from Tripterygium wilfordii. Acta Acad. Med. Sinicae 1987; 9: 323-8.
41. Kupchan SM, Court WA, Daily RG et al. Triptolide and tripdiolide, a new novel antileukemic diterpenoid triepoxides from Tripterygium wilfordii. J. Am. Chem. Soc. 1972; 94: 7194-5.