Attenuation of pressure-induced myogenic contraction and tyrosine phosphorylation by fasudil, a cerebral vasodilator, in rat cerebral artery

British Journal of Pharmacology

Volumn 130, Issue 2, 2000, Pages 219-230

  Masumoto, Naohiro ^a   Tanabe, Yoshiyuki ^a   Saito, Maki ^a   Nakayama, Koichi ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Fasudil; Herbimycin A; Immunocytochemistry; Myogenic contraction; Nicardipine; pp60(src) activity; Rat cerebral artery; Tyrosine phosphorylation

Indexed keywords

ARGINYLGLYCYLASPARTYLSERINE; CALCIUM ION; FASUDIL; GENISTEIN; HERBIMYCIN A; NICARDIPINE; ORTHOVANADIC ACID; PERIPHERAL VASODILATING AGENT; PROTEIN KINASE P60;

ANIMAL TISSUE; ARTERY DIAMETER; ARTICLE; BRAIN ARTERY; CALCIUM CELL LEVEL; CELL FREE SYSTEM; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; IMMUNOCYTOCHEMISTRY; MALE; MUSCLE CONTRACTION; NONHUMAN; PRESSURE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT;

EID: 0034064714     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703292     Document Type: Article

References (43)

1. ASANO, T., IKEGAKI, I., SATOH, S., SUZUKI, Y., SHIBUYA, M., TAKAYASU, M. & HIDAKA, H. (1987). Mechanism of action of a novel antivasospasm drug, HA1077. J. Pharmacol. Exp. Ther., 241, 1033-1040.
2. ASANO, T., SUZUKI, T., TSUCHIYA, M., SATOH, S., IKEGAKI, I., SHIBUYA, M., SUZUKI, Y. & HIDAKA, H. (1989). Vasodilator actions of HA1077 in vitro and in vivo putatively mediated by the inhibition of protein kinase. Br. J. Pharmacol., 98, 1091-1100.
3. D'ANGELO, G., DAVIS, M.J. & MEININGER, G.A. (1997a). Calcium and mechanotransduction of the myogenic response. Am. J. Physiol., 273, H175-H182.
4. i induced by RGD-containing peptide. Am. J. Physiol., 272, H2065-H2070.
5. 2+ in cultured smooth muscle cells. Am. J. Physiol, 263, C95-C105.
6. HWANG, T.-C., WANG, F., YANG, I.C.-H. & REENSTRA, W.W. (1997). Genistein potentiates wild-type and ΔF508-CFTR channel activity. Am. J. Physiol., 273, C988-C998.
7. INGBER, D. (1991). Integrins as mechanochemical transducers. Curr. Opin. Cell. Biol., 3, 841-848.
8. (1)-Nitro-L-arginine: a potent inhibitor of endothelium-derived relaxing factor formation. Eur. J. Pharmacol., 176, 219-223.
9. IWABUCHI, S., MARTON, L.S. & ZHANG, J.H. (1999). Role of protein tyrosine phosphorylation in crythrocyte lysate-induced intracellular free calcium concentration elevation in cerebral smooth-muscle cells. J. Neurosurg., 90, 743-751.
10. KATSUMATA, N., SHIMOKAWA, H., SETO, M., KOZAI, T., YAMAWAKI, T., KUWATA, K., EGASHIRA, K., IKEGAKI, I., ASANO, T., SASAKI, Y. & TAKESHITA, A. (1997). Enhanced myosin light chain phosphorylations as a central mechanism for coronary artery spasm in a swine model with interleukin-1β. Circulation, 96, 4357-4363.
11. KIM, C.J., KIM, K.W., PARK, J.W., LEE, J.C. & ZHANG, J.H. (1998). Role of tyrosine kinase in erythrocyte lysate-induced contraction in rabbit cerebral arteries. J. Neurosurg., 89, 289-296.
12. LANGTON, P.D. (1993). Calcium channel currents recorded from isolated myocytes of rat basilar artery are stretch sensitive. J. Physiol., 471, 1-11.
13. LEHOUX, S. & TEDGUI, A. (1998). Signal transduction of mechanical stress in the vascular wall. Hypertension, 23, 338-345.
14. LIU, C.Y. & STUREK, M. (1996). Attenuation of endothelin-1-induced calcium response by tyrosine kinase inhibitors in vascular smooth muscle cells. Am. J. Physiol., 270, C1825-C1833.
15. i elevation induced by hemolysate in bovine endothelial cells: Implications for cerebral vasospasm. Neurol. Res., 18, 349-353.
16. MASUMOTO, N., NAKAYAMA, K., OYABE, A., UCHINO, M., ISHII, K., OBARA, K. & TANABE, Y. (1997). Specific attenuation of the pressure-induced contraction of rat cerebral artery by herbimycin A. Eur. J. Pharmacol., 330, 55-63.
17. MEININGER, G.A., ZAWIEJA, D.C., FALCONE, J.C., HILL, M.A. & DAVEY, J.P. (1991). Calcium measurement in isolated arterioles during myogenic and agonist stimulation. Am. J. Physiol., 261, H950-H959.
18. 3 integrin mediates arteriolar vasodilation in response to RGD peptides. Circ. Res., 79, 821-826.
19. MULLER, J.M., CHILIAN, W.M. & DAVIS, M.J. (1997). Integrin signaling transduces shear stress-dependent vasodilation of coronary arterioles. Circ. Res., 80, 320-326.
20. MULLER, J.M., DAVIS, M.J. & CHILIAN, W.M. (1996). Coronary arteriolar flow-induced vasodilation signals through tyrosine kinase. Am. J. Physiol., 270, H1878-H1884.
21. NAKAYAMA, K. (1982). Calcium-dependent contractile activation of cerebral artery produced by quick stretch. Am. J. Physiol., 242, H760-H768.
22. NAKAYAMA, K. (1988). Active and passive mechanical properties of ring and spatial segments of isolated dog basilar artery assessed by electrical and pharmacological stimulations. Blood Vessels, 25, 285-298.
23. NAKAYAMA, K. & TANAKA, Y. (1988). Calcium transients and stretch-induced myogenic tone in vascular tissue. In: Resistance Arteries, ed. Halpern, W. et al. pp. 212-218. New York: Periatology Press.
24. NAKAYAMA, K., TANAKA, Y. & FUJISHIMA, K. (1989). Potentiation of stretch-induced myogenic tone of dog cerebral artery by hemolysate and inhibitory action of calcium antagonists. Eur. J. Pharmacol., 169, 33-42.
25. OHANIAN, J., OHANIAN, V., SHAW, L., BRUCE, C. & HEAGERTY, A.M. (1997). Involvement of tyrosine phosphorylation in endothelin-1-induced calcium-sensitization in rat small mesenteric arteries. Br. J. Pharmacol., 120, 653-661.
26. OSOL, G. (1995). Mechanotransduction by vascular smooth muscle. J. Vasc. Res., 32, 275-292.
27. c-src. Cell, 49, 75-82.
28. ROHRSCHNEIDER, L.R. (1980). Adhesion plaques of Rous sarcoma virus-transformed cells contain the src gene product. Proc. Natl. Acad. Sci. U.S.A., 77, 3514-3518.
29. ROHRSCHNEIDER, L.R., EISENMAN, R.N. & LEITCH, C.R. (1979). Identification of a Rous sarcoma virus transformation-related protein in normal avian and mammalian cells. Proc. Natl. Acad. Sci. U.S.A., 76, 4479-4483.
30. RUOSLAHTI, E. & PIERSBACHER, M.D. (1986). Arg-Gly-Asp: a versatile cell recognition signal. Cell, 44, 517-518.
31. RUOSLAHTI, E. & PIERSBACHER, M.D. (1987). New perspectives in cell adhesion: RGD and integrins. Science, 238, 491-497.
32. SAITO, M., TANABE, Y., MASUMOTO, N., ISHIKAWA, T., OBARA, K., HORIE, N., TAKEISHI, K. & NAKAYAMA, K. (1999). Differential augmentation by mechanical stretch of protein tyrosine phosphorylation in medial smooth muscle and endothelial cells isolated from rabbit pulmonary arteries. Japan. J. Pharmacol., 79 (Suppl. 1): 85.
33. SCHRAAG, B., STAAL, G.E.J., ADRIAANSEN-SLOT, S.S., SALDEN, M. & RIJKSEN, G. (1993). Standardization of an enzyme-linked immunosorbent assay for the determination of protein tyrosine kinase activity. Anal. Biochem., 211, 233-239.
34. SCHWARTZ, M.A., BROWN, E.J. & FAZELI, B. (1993). A 50-kDa integrin-associated protein is required for integrin-regulated calcium entry in endothelial cells. J. Biol. Chem., 268, 19931-19934.
35. SETO, M., SASAKI, Y., SASAKI, Y. & HIDAKA, H. (1991). Effects of HA1077, a protein kinase inhibitor, on myosin phosphorylation and tension in smooth muscle. Eur. J. Pharmacol., 195, 267-272.
36. SETO, M., SHINDO, K., ITO, K. & SASAKI, Y. (1995). Selective inhibition of phosphorylation and tension of hyperplastic arteries by the kinase inhibitor HA1077. Eur. J. Pharmacol., 276, 27-33.
37. SHIROTANI, M., YUI, Y., HATTORI, R. & KAWAI, C. (1991). A new type of vasodilator, HA1077, an isoquinoline derivative, inhibits proliferation of bovine vascular smooth muscle cells in culture. J. Phamarol. Exp. Ther., 259, 738-744.
38. TAKAYASU, M., SUZUKI, Y., SHIBUYA, M., ASANO, T., KANAMORI, M., OKADA, T., KAGEYAMA, N. & HIDAKA, H. (1986). The effects of HA compound calcium antagonists on delayed cerebral vasospasm in dogs. J. Neurosurg., 65, 80-85.
39. 2+ level and contraction in vascular smooth muscle. Eur. J. Pharmacol., 250, 431-437.
40. 2+ handling mechanisms underlying neuropeptide Y-induced contraction in canine basilar artery. Eur. J. Pharmacol., 289, 59-66.
41. UEHATA, M., ISHIZAKI, T., SATOH, H., ONO, T., KAWAHARA, T., MORISHITA, T., TAMAKAWA, H., YAMAGAMI, K., INUI, J., MAEKAWA, M. & NARUMIYA, S. (1997). Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature, 389, 990-994.
42. WIJETUNGE, S. & HUGHES, A.D. (1996). Activation of endogenous c-Src or a related tyrosine kinase by intracellular (pY)EEI peptide increases voltage-operated calcium channel currents in rabbit ear artery cells. FEBS Lett., 399, 63-66.
43. - channel in guinea pig ventricular myocytes and CFTR-transfected mouse fibroblasts. Japan. J. Physiol., 48, 389-396.