A preliminary study of photodynamic therapy using verteporfin for choroidal neovascularization in pathologic myopia, ocular histoplasmosis syndrome, angioid streaks, and idiopathic causes

Archives of Ophthalmology

Volumn 118, Issue 3, 2000, Pages 327-336

  Sickenberg, Michel ^a,b   Schmidt Erfurth, Ursula ^c   Miller, Joan W ^c   Pournaras, Constantin J ^c   Zografos, Leonidas ^c   Piguet, Bertrand ^c   Donati, Guy ^c   Laqua, Horst ^c   Barbazetto, Irene ^c   Gragoudas, Evangelos S ^c   Lane, Anne Marie ^c   Birngruber, Reginald ^c   Van Den Bergh, Hubert ^c   Strong, H Andrew ^c   Manjuris, Ulrike ^c   Gray, Todd ^c   Fsadni, Mario ^c   Bressler, Neil M ^c  

^a HÔPITAL OPHTALMIQUE JULES GONIN   (Switzerland)

^b CIBA Vision Corporation   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

BENZOPORPHYRIN DERIVATIVE;

ANGIOID STREAK; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG EFFICACY; DRUG SAFETY; FEMALE; FLUORESCENCE ANGIOGRAPHY; HUMAN; MALE; MULTICENTER STUDY; MYOPIA; OCULAR HISTOPLASMOSIS; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; SUBRETINAL NEOVASCULARIZATION; TREATMENT OUTCOME; VISUAL ACUITY;

EID: 0034064326     PISSN: 00039950     EISSN: None     Source Type: Journal    
DOI: 10.1001/archopht.118.3.327     Document Type: Article

References (22)

1. Gass JDM. Pathgenesis of disciform detachment of the neuroepithelium, III: senile disciform macular degeneration. Am J Ophthalmol. 1967;63:617-644.
2. Green WR, Wilson DJ. Choroidal neovascularization. Ophthalmology. 1986;93: 1169-1176.
3. Green WR. Clinicopathologic studies of treated choroidal neovascular membranes: a review and report of two cases. Retina. 1991;11:328-356.
4. Freund KB, Yannuzzi LA, Sorenson JA. Age-related macular degeneration and choroidal neovascularization. Am J Ophthalmol. 1993;115:786-791.
5. Weishaupt KR, Gomer CJ, Dougherty TJ. Identification of singlet oxygen as the cytotoxic agent in photo-inactivation of a murine tumor. Cancer Res. 1976;36: 2326-2329.
6. Zhou C. Mechanisms of tumor necrosis induced by photodynamic therapy. J Photochem Photobiol B. 1989;3:299-318.
7. Miller H, Miller B. Photodynamic therapy of subretinal neovascularization in the monkey eye. Arch Ophthalmol. 1993;111:855-860.
8. Fingar VH, Wieman TJ, Wiehle SA, Cerrito PB. The role of microvascular damage in photodynamic therapy: the effect of treatment on vessel constriction, permeability and leukocyte adhesion. Cancer Res. 1992;52:4914-4921.
9. Schmidt-Erfurth U, Hasan T, Schomacker K, Flotte TJ, Birngruber R. In vivo uptake of liposomal benzoporphyrin derivative and photothrombosis in experimental corneal neovascularization. Lasers Surg Med. 1995;17:178-188.
10. Schmidt-Erfurth U, Bauman W, Gragoudas E, Michaud NA, Birngruber R, Hasan T. Photodynamic therapy of experimental choroidal melanoma using lipoprotein-delivered benzoporphyrin. Ophthalmology. 1994;101:89-99.
11. Schmidt-Erfurth U, Hasan T, Gragoudas E, Michaud N, Flotte TJ, Birngruber R. Vascular targeting in photodynamic occlusion of subretinal vessels. Ophthalmology. 1994;101:1953-1961.
12. Husain D, Miller JW, Michaud N, Connolly E, Flotte TJ, Gragoudas ES. Intravenous infusion of liposomal benzoporphyrin derivative for photodynamic therapy of experimental choroidal neovascularization. Arch Ophthalmol. 1996;114:978-985.
13. Miller JW, Walsh AW, Kramer M, et al. Photodynamic therapy of experimental choroidal neovascularization using lipoprotein-delivered benzoporphyrin. Arch Ophthalmol. 1995;113:810-818.
14. Kramer M, Miller JW, Michaud N, et al. Liposomal benzoporphyrin derivative verteporfin in photodynamic therapy: selective treatment of choroidal neovascularization in monkeys. Ophthalmology, 1996;103:427-438.
15. Husain D, Kramer M, Kenney AG, Michaud N, Flotte TJ, Gragoudas ES, Miller JW. Effects of photodynamic therapy using verteporfin on experimental choroidal neovascularization and normal retina and choroid up to seven weeks after treatment. Invest Ophthalmol Vis Sci. 1999;40:2322-2231.
16. Reinke MH, Canakis C, Husain D, Michaud N, Flotte TJ, Gragoudas ES, Miller JW. Verteporfin photodynamic therapy retreatment of normal retina and choroid in the cynomolgus monkey. Ophthalmology. 1999;106:1915-1923.
17. Miller JW, Schmidt-Erfurth U, Sickenberg M, et al. Photodynamic therapy with verteporfin for choroidal neovascularization caused by age-related macular degeneration: results of a single treatment in a phase 1 and 2 study. Arch Ophthalmol. 1999;117:1161-1173.
18. Schmidt-Erfurth U, Miller JW, Sickenberg M, et al. Photodynamic therapy of choroidal neovascularization caused by age-related macular degeneration: results of retreatments in a phase 1 and 2 study. Arch Ophthalmol. 1999;117:1177-1187.
19. Chamberlain JA, Bressler NM, Bressler SB, et al. The use of fundus photographs and fluorescein angiograms in the identification and treatment of choroidal neovascularization in the Macular Photocoagulation Study. Ophthalmology. 1989;96:1526-1534.
20. Macular Photocoagulation Study Group. Five-year follow-up of fellow eyes of individuals with ocular histoplasmosis and unilateral extrafoveal or juxtafoveal choroidal neovascularization. Arch Ophthalmol. 1996;114:677-688.
21. TAP Study Group. Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: one-year results of 2 randomized clinical trials - TAP Report 1. Arch Ophthalmol. 1999;117:1329-1345.
22. Slakter J, and VIP Study Group. Photodynamic therapy of subfoveal choroidal neovascularization in pathologic myopia with verteporfin: study design and baseline characteristics in the VIP randomized clinical trial [abstract]. Invest Ophthalmol Vis Sci. 1999;40:S401.