Papillary and follicular neoplasms of the thyroid gland: Differential immunohistochemical staining with high-molecular-weight keratin and involucrin

Applied Immunohistochemistry

Volumn 8, Issue 1, 2000, Pages 42-48

  Liberman, Eva ^a   Weidner, Noel ^b,c  

^a Seton Medical Center   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cytokeratin; Follicular neoplasms; Papillary carcinoma; Thyroid gland

Indexed keywords

ARTICLE; ASPIRATION BIOPSY; CANCER CLASSIFICATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; THYROID FOLLICULAR CARCINOMA; THYROID PAPILLARY CARCINOMA;

ADENOCARCINOMA, FOLLICULAR; CARCINOMA, PAPILLARY; CARCINOMA, PAPILLARY, FOLLICULAR; DIAGNOSIS, DIFFERENTIAL; HUMANS; IMMUNOHISTOCHEMISTRY; KERATINS; PROTEIN PRECURSORS; THYROID NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 0034063583     PISSN: 10623345     EISSN: None     Source Type: Journal    
DOI: 10.1097/00022744-200003000-00007     Document Type: Article

References (17)

1. Baloch ZW, Gupta PK, Sack MJ, LiVolsi VA. Follicular variant of papillary carcinoma. Cytologic and histologic correlation. Am J Clin Pathol 1999;111:216-22.
2. Carcangio ML, Zampi, G, Pupi A, Castoagnoli A, Rosai J. Papillary carcinoma of the thyroid: a clinicopathologic study of 241 cases treated at the University of Florence, Italy. Cancer 1985;55: 805-28.
3. Carcangiu ML, Zampi G, Rosai J. Papillary thyroid carcinoma: a study of its many morphologic expressions and clinical correlates. Pathol Annu 1985;20:1-44.
4. Franssila KO. Value of histologic classification of thyroid cancer. Acta Pathol Microbiol Scand Suppl 1981;225:5-76.
5. LiVolsi VA. Papillary neoplasms of the thyroid. Pathologic and prognostic features. Am J Clin Pathol 1992;97:426-34.
6. Katoh R, Sakamoto A, Kasai N, Tagawa K. Squamous differentiation in thyroid carcinoma. With special reference to histogenesis of squamous cell carcinoma of the thyroid. Acta Pathol Jpn 1989; 39:306-12.
7. Akslen LA, Myking AO. Differentiated thyroid carcinomas: the relevance of various pathological features for tumour classification and prediction of tumour progress. Virchows Arch A Pathol Anat Histopathol 1992;421:17-23.
8. Park SH, Suh EH, Chi JG. A histopathologic study on 1,095 surgically resected thyroid specimens. Jpn J Clin Oncol 1988;18:297-302.
9. Miller TR, Bottles K, Holly EA, Friend NF, Abele JS. A step-wise logistic regression analysis of papillary carcinoma of the thyroid. Acta Cytol 1986;30:285-93.
10. Fonseca E, Nesland JM, Hoie J, Sobrinho-Simoes M. Patterns of expression of intermediate cytokeratin filaments in the thyroid gland: an immunohistochemical study of simple and stratified epithelial-type cytokeratins. Virchows Arch 1997;430:239-46.
11. Raphael SJ, McKeown-Eysson G, Asa SL. High molecular weight cytokeratin and cytokeratin-19 in the diagnosis of thyroid tumors. Mod Pathol 1994;7:295-300.
12. Raphael SJ, Apel RL, Asa SL. Brief report detection of high molecular weight cytokeratins in neoplastic and non-neoplastic thyroid tumors using microwave antigen retrieval. Mod Pathol 1995;8:870-2.
13. Permanetter W, Nathrath WBJ, Lohrs U. Immunohistochemical analysis of thyroglobulin and keratin in benign and malignant thyroid tumours. Virchows Arch A Pathol Anat Histopathol 1982;398: 221-8.
14. Miettinen M, Kovatich AJ, Karkkainen P. Keratin subsets in papillary and follicular thyroid lesions. A paraffin section analysis with diagnostic implications. Virchows Arch 1997;431:407-13.
15. Schelfhout LJ, Van Muijen GN, Fleuren GJ. Expression of keratin 19 distinguishes papillary thyroid carcinoma from follicular carcinomas and follicular thyroid adenoma. Am J Clin Pathol 1989;92: 654-8.
16. Schroder S, Wodzynski A, Padberg B. Cytokeratin expression of benign and malignant epithelial thyroid gland tumors. An immunohistologic study of 154 neoplasms using 8 different monoclonal cytokeratin antibodies. Pathologe 1996;17:425-32.
17. Jennings TA, Boguniewicz AB, Sheehan CE, Figge J. Involucrin selectively stains papillary thyroid carcinoma. Appl Immunohistochem 1998;6:55-61.