Pattern of expression of intermediate cytokeratin filaments in the thyroid gland: An immunohistochemical study of simple and stratified epithelial-type cytokeratins

Virchows Archiv

Volumn 430, Issue 3, 1997, Pages 239-245

  Fonseca, Elsa ^a,c   Nesland, Jahn M ^b   Höie, Johan ^b   Sobrinho Simões, Manuel ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF OSLO   (Norway)

^c University of Porto   (Portugal)

Author keywords

Cytokeratin filaments; Follicular carcinoma; Immunohistochemistry; Papillary carcinoma

Indexed keywords

CYTOKERATIN;

ARTICLE; CELL TRANSFORMATION; CONTROLLED STUDY; EPITHELIUM; FOLLICULAR CARCINOMA; HASHIMOTO DISEASE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INTERMEDIATE FILAMENT; PAPILLARY CARCINOMA; PARENCHYMA; PRIORITY JOURNAL; THYROID CARCINOMA; THYROID GLAND; TUMOR DIFFERENTIATION; TUMOR GROWTH;

ADENOCARCINOMA, FOLLICULAR; CARCINOMA, PAPILLARY; EPITHELIUM; HUMANS; IMMUNOHISTOCHEMISTRY; INTERMEDIATE FILAMENTS; KERATINS; REFERENCE VALUES; THYROID GLAND; THYROID NEOPLASMS; THYROIDITIS;

EID: 0030943220     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01324808     Document Type: Article

References (31)

1. Bosch F, Leube R, Achtstätter T, Moll R, Franke R (1988) Expression of simple epithelial-type cytokeratins in stratified epithelia as detected by immunolocalization and hybridization in situ. J Cell Biol 106:1635-1648
2. Broers J, Ramaekers F, Rot M, Oostendorp T, Huysmans A, van Muijen G, Wagenaar S, Vooijs G (1988) Cytokeratins in different types of human lung cancer as monitored by chain-specific monoclonal antibodies. Cancer Res 48:3221-3229
3. Buley I, Gatter K, Heryet A, Mason D (1987) Expression of intermediate filament proteins in normal and diseased thyroid glands. J Clin Pathol 40:136-142
4. Chu Y, Runyan R, Oshima R, Hendrix M (1993) Expression of complete keratin filaments in mouse L cells augments cell migration and invasion. Proc Natl Acad Sci USA 90:4261-4265
5. Diaz-Guerra M, Haddow S, Bauluz C, Jorcano J, Cano A, Balmain A, Quintanilla M (1992) Expression of simple epithelial cytokeratins in mouse epidermal keratinocytes harboring Harvey ras alterations. Cancer Res 52:680-687
6. Dockhorn-Dworniczak B, Franke W, Schröder S, Czernobilsky B, Gould V, Böcker W (1987) Patterns of expression of cytoskeletal proteins in human thyroid gland and thyroid carcinomas. Differentiation 35:53-71
7. Heatley M, Maxwell P, Whiteside C, Toner P (1995) Cytokeratin intermediate filament expression in benign and malignant breast disease. J Clin Pathol 48:26-32
8. Hedinger C, Williams E, Sobin L (1988) Histologic typing of thyroid tumours. World Health Organization Histological Classification of Tumors. Springer, Berlin Heidelberg New York
9. Hedrick L, Epstein J (1989) Use of keratin 903 as an adjunct in the diagnosis of prostate carcinoma. Am J Surg Pathol 13:389-396
10. Hendrix M, Seftor E, Chu Y-W, Seftor R, Nagle R, McDaniel K, Leng S, Yohem K, Leibovitz A, Meyskens F, Conaway D, Welch D, Liotta L, Stetler-Stevenson W (1992) Coexpression of vimentin and keratins by human melanoma tumour cells: correlation with invasive and metastatic potential. J Natl Cancer Inst 84:165-174
11. Henzen-Logmans S, Mullink H, Ramaekers F, Tadema T, Meijer C (1987) Expression of cytokeratins and vimentin in epithelial cells of normal and pathologic thyroid tissue. Virchows Arch [A] 410:347-354
12. Lane E, Alexander C (1990) Use of keratin antibodies in tumour diagnosis. Semin Cancer Biol 1:165-179
13. Lapis K, Sarosi I, Bocsi J, Thorgeirsson U (1995) Cytokeratin patterns of liver carcinomas induced by diethylnitrosamine in monkeys. Lab Invest 72:748-759
14. LiVolsi V (1990) Surgical pathology of the thyroid. Saunders, Philadelphia
15. Miettinen M. (1993) Keratin immunohistochemistry: update of applications and pitfalls. Pathol Annu 28:113-143
16. Miettinen M, Franssila K, Lehto V-P, Paasivuo R, Virtanen I (1984) Expression of intermediate filament proteins in thyroid gland and thyroid tumours. Lab Invest 50:262-270
17. Moll R (1992) Molecular diversity of cytokeratins: significance for cell and tumour differentiation. Acta Histochem Suppl 61:117-127
18. Moll R, Franke W, Shiller D (1982) The catalog of human cytokeratins: patterns of expression in normal epithelia, tumours and cultured cells. Cell 31:11-24
19. Moll R, Lowe A, Laufer J, Franke W (1992) Cytokeratin 20 in human carcinomas. A new histodiagnostic marker detected by monoclonal antibodies. Am J Pathol 140:427-447
20. Morgan P, Su L (1994) Intermediate filaments in oral neoplasia. I. Oral cancer and epithelial dysplasia. Eur J Cancer [B] 30:160-166
21. Pankov R, Umezawa A, Maki R, Der C, Hause C, Oshima R (1994) Oncogene activation of human keratin 18 transcription via the Ras signal transduction pathway. Proc Natl Acad Sci USA 92:873-877
22. Ramaekers F, van Niekerk C, Poels L, Schaafsma H, Huijsmans A, Robben H, Schaart G, Vooijs P (1990) Use of monoclonal antibodies to keratin 7 in the differential diagnosis of adenocarcinomas. Am J Pathol 136:641-655
23. Raphael S, McKeown G, Asa S (1994) High-molecular-weight cytokeratins and cytokeratin 19 in the diagnosis of thyroid tumours. Mod Pathol 7:295-300
24. Raphael S, Apel R, Asa S (1995) Detection of high-molecular-weight cytokeratins in neoplastic and non-neoplastic thyroid tumours using microwave antigen retrieval. Mod Pathol 8:870-872
25. Schaafsma H, Ramaekers F, vanMuijen G, Robben H, Lane E, Leigh I, Ooms E, Schalken J, Moorselaar R, Ruiter D (1991) Cytokeratin expression pattern in metastatic transitional cell carcinomas of the urinary tract. An immunohistochemical study comparing local tumour and autologous metastases. Am J Pathol 139:1389-1400
26. Schaafsma H, Van der Velden L, Manni J, Peters H, Link M, Ruiter D, Ramaekers F (1993) Increased expression of cytokeratins 8, 18 and vimentin in the invasion front of mucosal squamous cell carcinoma. J Pathol (Lond) 170:77-87
27. Schelfhout L, vanMuijen G, Fleuren G (1989) Expression of keratin 19 distinguishes papillary thyroid carcinoma from follicular carcinoma and follicular thyroid adenoma. Am J Clin Pathol 92:654-658
28. Schröder S, Dockhorn-Dworniczak B, Kastendieck H, Böcker W, Franke W (1986) Intermediate-filament expression in thyroid gland carcinomas. Virchows Arch [A] 409:751-766
29. Smedts F, Ramaekers F, Troyanovsky S, Pruszczynski M, Link M, Lane B, Leigh I, Schijf C, Vooijs P (1992) Keratin expression in cervical cancer. Am J Pathol 141:497-511
30. Su L, Morgan P, Lane B (1994) Protein and mRNA expression of simple epithelial keratins in normal, dysplastic, and malignant oral epithelia. Am J Pathol 145:1349-1357
31. Uchida H, Nakayama I, Noguchi S (1989) An immunohistochemical study of cytokeratin and vimentin in benign and malignant thyroid lesions. Acta Pathol Jpn 39:169-175