pUL25 immunolocalization in human cytomegalovirus-infected and gene-transfected cells

Archives of Virology

Volumn 145, Issue 4, 2000, Pages 795-803

  Zini, N ^a   Santi, S ^a   Riccio, M ^a   Landini, M P ^b   Battista, M C ^b   Maraldi, N M ^a  

^a RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CELL; CONFOCAL LASER MICROSCOPY; CYTOPLASM; ELECTRON MICROSCOPY; GENETIC TRANSFECTION; HUMAN CYTOMEGALOVIRUS; PROTEIN AGGREGATION; PROTEIN LOCALIZATION; PUL25 PROTEIN; VIRION; VIRUS INFECTION;

ANIMALIA; DNA VIRUSES; HUMAN HERPESVIRUS 5; MIRIDAE;

EID: 0034063455     PISSN: 03048608     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007050050672     Document Type: Article

References (20)

1. 1. Ace CI, McKee TA, Ryan JM, Cameron JM, Preston CM (1989) Construction and characterization of a herpes simplex virus type 1 mutant unable to transduce immediate-early gene expression. J Virol 63: 2260-2269
2. 2. Baldick CJ Jr, Shenk T (1996) Proteins associated with purified human cytomegalovirus particles. J Virol 70: 6097-6105
3. 3. Battista MC, Bergamini G, Boccuni MC, Campanini F, Ripalti A, Landini MP (1999) Expression and characterization of a novel structural protein of human cytomegalovirus, pUL25. J Virol 73: 3800-3809
4. 4. Campbell ME, Palfreyman JW, Preston CM (1984) Identification of herpes simplex virus DNA sequences which encode a trans-acting polypeptide responsible for stimulation of immediate early transcription. J Mol Biol 180: 1-19
5. 5. Chee MS, Bankier AT, Beck S, Bohni R, Brown CM, Cerny R, Horsnell T, Hutchison III CA, Kouzarides T, Martignetti JA, Preddie E, Satchwell SC, Tomlison P, Weston KM, Barrell, BG (1990) Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169. Curr Top Microbiol Immunol 154: 125-169
6. 6. Chen DH, Jiang H, Liu F, Zhou ZH (1999) Three dimensional visualization of the tegument/capsid interactions in the intact human cytomegalovirus. Virol 260: 10-16
7. 7. Gibson W (1996) Structure and assembly of the virion. Intervirology 39: 389-400
8. 8. Hensel GM, Meyer HH, Buchmann I, Pommerehne D, Schmolke S, Plachter B, Radask K, Kern HF (1996) Intracellular localization and expression of the human cytomegalovirus matrix phosphoprotein pp71 (ppUL82): evidence for its translocation into the nucleus. J Gen Virol 77: 3087-3097
9. 9. Landini MP, Severi B, Furlini G, Badiali De Giorgi L (1987) Human cytomegalovirus structural components: intracelluar and intraviral localization of p28 and p65-69 by immunoelectron microscopy. Virus Res 8: 15-23
10. 10. Liu B, Stinski MF (1992) Human cytomegalovirus contains a tegument protein that enhances transcription from promoters with upstream ATF and AP-1 cis-acting elements. J Virol 66: 4434-4444
11. 11. Rixon FJ (1993) Structure and assembly of herpesviruses. Semin Virol 4: 135-144
12. rd Herpesvirus Workshop
13. 13. Schmolke S, Drescher P, Jahn G, Plachter B (1995) Nuclear targeting of the tegument protein pp65 (UL83) of human cytomegalovirus: an unusual bipartite nuclear localization signal functions with other portions of the protein to mediate its efficient nuclear transport. J Virol 69: 1071-1078
14. 14. Severi B, Landini MP, Cenacchi G, Zini N, Maraldi NM (1992) Human cytomegalovirus nuclear and cytoplasmic dense bodies. J Arch Virol 123: 193-207
15. 15. Stefan A, Secchiero P, Baechi T, Kempf W, Campadelli-Fiume G (1997) The 85-kilodalton phosphoprotein (pp85) of Human Herpesvirus 7 is encoded by open reading frame U14 and localizes to a tegument substructure in virion particles. J Virol 71: 5758-5763
16. 16. Trus BL, Gibson W, Cheng N, Steven AC (1999) Capsid structure of simian cytomegalovirus from cryoelectron microscopy: evidence for tegument attachment sites. J Virol 73: 2181-2192
17. 17. Zini N, Battista MC, Santi S, Riccio M, Bergamini G, Landini MP, Maraldi NM (1999) The novel structural protein of human cytomegalovirus, pUL25, is localized in the viral tegument. J Virol 73: 6073-5
18. 18. Weinheimer SP, Boyd, BA, Durham SK, Resnik JL, O'Boyle DR (1992) Deletion of the VP16 open reading frame of herpes simplex virus type 1. J Virol 66: 258-269
19. 19. Winkler M, Stamminger T (1996) A specific subform of the human cytomegalovirus transactivator protein pUL69 is contained within the tegument of virus particles. J Virol 70: 8984-8987
20. 20. Yao F, Courtney RJ (1992) Association of ICP0 but not ICP27 with purified virions of herpes simplex virus type 1. J Virol 66: 2709-2716