-
1
-
-
0030469421
-
Preclinical antitumor activity of CI-994
-
LoRusso, P., Demchik, L., Foster, B., Knight, J., Bissery, M-C., Polin, L., Leopold, W., and Corbett, T. Preclinical antitumor activity of CI-994. Investig. New Drugs, 14: 349-356, 1996.
-
(1996)
Investig. New Drugs
, vol.14
, pp. 349-356
-
-
LoRusso, P.1
Demchik, L.2
Foster, B.3
Knight, J.4
Bissery, M.-C.5
Polin, L.6
Leopold, W.7
Corbett, T.8
-
2
-
-
0027185184
-
Acetyldinaline: A new oral cytostatic drug with impressive differential activity against leukemia cells and normal stem cells - Preclinical studies in a relevant rat model for human acute myelocytic leukemia
-
El-Beltagi, H., Martens, A., Lelieveld, P., Haroun, E., and Hagenbeek, A. Acetyldinaline: a new oral cytostatic drug with impressive differential activity against leukemia cells and normal stem cells - preclinical studies in a relevant rat model for human acute myelocytic leukemia. Cancer Res., 53: 3008-3014, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 3008-3014
-
-
El-Beltagi, H.1
Martens, A.2
Lelieveld, P.3
Haroun, E.4
Hagenbeek, A.5
-
3
-
-
0027429192
-
Efficacy of acetyldinaline for treatment of minimal residual disease (MRD): Preclinical studies in the BNML rat model for human acute myelocytic leukemia
-
Baltimore
-
El-Beltagi, H., Martens, A., Dahab, G., and Hagenbeek, A. Efficacy of acetyldinaline for treatment of minimal residual disease (MRD): preclinical studies in the BNML rat model for human acute myelocytic leukemia. Leukemia (Baltimore), 7: 1795-1800, 1993.
-
(1993)
Leukemia
, vol.7
, pp. 1795-1800
-
-
El-Beltagi, H.1
Martens, A.2
Dahab, G.3
Hagenbeek, A.4
-
4
-
-
0030271680
-
Efficacy of dinaline and its methyl and acetyl derivatives against colorectal cancer in vivo or in vitro
-
Seelig, M., and Berger, M. Efficacy of dinaline and its methyl and acetyl derivatives against colorectal cancer in vivo or in vitro. Eur. J. Cancer, 32A: 1968-1976, 1996.
-
(1996)
Eur. J. Cancer
, vol.32 A
, pp. 1968-1976
-
-
Seelig, M.1
Berger, M.2
-
5
-
-
0025668586
-
New cytostatics - More activity and less toxicity
-
Berger, M., Richter, H., Seelig, M., Eibl, H., and Schmahl, D. New cytostatics - more activity and less toxicity. Cancer Treat. Rev., 17: 143-154, 1990.
-
(1990)
Cancer Treat. Rev.
, vol.17
, pp. 143-154
-
-
Berger, M.1
Richter, H.2
Seelig, M.3
Eibl, H.4
Schmahl, D.5
-
6
-
-
0031415761
-
Preclinical toxicity of a new oral anticancer drug, CI-994 (acetyl dinaline) in rats and dogs
-
Graziano, M., Pilcher, G., Walsh, K., Kasali, O., and Radovic, L. Preclinical toxicity of a new oral anticancer drug, CI-994 (acetyl dinaline) in rats and dogs. Investig. New Drugs, 15: 295-310, 1997.
-
(1997)
Investig. New Drugs
, vol.15
, pp. 295-310
-
-
Graziano, M.1
Pilcher, G.2
Walsh, K.3
Kasali, O.4
Radovic, L.5
-
7
-
-
0029099455
-
Role of a small molecular weight phosphoprotein in the mechanism of action of CI-994 (N-acetyldinaline)
-
Rummel, S., Kraker, A., Steinkarnpf, R., Hook, K., and Klohs, W. Role of a small molecular weight phosphoprotein in the mechanism of action of CI-994 (N-acetyldinaline). Int. J. Cancer, 62: 636-642, 1995.
-
(1995)
Int. J. Cancer
, vol.62
, pp. 636-642
-
-
Rummel, S.1
Kraker, A.2
Steinkarnpf, R.3
Hook, K.4
Klohs, W.5
-
8
-
-
0013587668
-
Phase I clinical trial of CI994
-
LoRusso, P., Wozniak, A., Foster, B., Zalupski, M., Shields, A., McCormick, J., Meyer, M., Radulovic, L., and Corbett, T. Phase I clinical trial of CI994. Proc. Am. Soc. Clin. Oncol., 16: 213a, 1997.
-
(1997)
Proc. Am. Soc. Clin. Oncol.
, vol.16
-
-
LoRusso, P.1
Wozniak, A.2
Foster, B.3
Zalupski, M.4
Shields, A.5
McCormick, J.6
Meyer, M.7
Radulovic, L.8
Corbett, T.9
-
9
-
-
0021984892
-
Effectiveness of P-aminobenzoyl-O-phenylenediamine (Goe 1734) against mouse, rat, and human tumour cells
-
Lelieveld, P., Middledorp, R., and van Putten, L. Effectiveness of P-aminobenzoyl-O-phenylenediamine (Goe 1734) against mouse, rat, and human tumour cells. Cancer Chemother. Pharmacol., 15: 88-90, 1985.
-
(1985)
Cancer Chemother. Pharmacol.
, vol.15
, pp. 88-90
-
-
Lelieveld, P.1
Middledorp, R.2
Van Putten, L.3
-
11
-
-
0025094445
-
A rhesus monkey model for continuous infusion of drugs into cerebrospinal fluid
-
McCully, C., Baus, F., Bacher, J., Phillips, J., and Poplack, D. A rhesus monkey model for continuous infusion of drugs into cerebrospinal fluid. Lab. Anim. Sci., 40: 522-525, 1990.
-
(1990)
Lab. Anim. Sci.
, vol.40
, pp. 522-525
-
-
McCully, C.1
Baus, F.2
Bacher, J.3
Phillips, J.4
Poplack, D.5
-
12
-
-
0030723231
-
Preclinical pharmacokinetic, antitumor and toxicity studies with CI-994 (N-acetyldinaline)
-
Foster, B., Jones, L., Wiegand, R., LoRusso, P., and Corbett, T. Preclinical pharmacokinetic, antitumor and toxicity studies with CI-994 (N-acetyldinaline). Investig. New Drugs, 15: 187-194, 1997.
-
(1997)
Investig. New Drugs
, vol.15
, pp. 187-194
-
-
Foster, B.1
Jones, L.2
Wiegand, R.3
LoRusso, P.4
Corbett, T.5
-
13
-
-
0018563907
-
MLAB - A mathematical modeling tool
-
Knott, G. MLAB - a mathematical modeling tool. Comput. Programs Biomed., 10: 271-280, 1979.
-
(1979)
Comput. Programs Biomed.
, vol.10
, pp. 271-280
-
-
Knott, G.1
-
14
-
-
0018091195
-
Application of Akaike's information criterion (AIC) in the evaluation of linear pharmacokinetic equations
-
Yamaoka, K., Nakagawa, T., and Uno, T. Application of Akaike's information criterion (AIC) in the evaluation of linear pharmacokinetic equations. J. Pharmacokinet. Biopharm., 6: 165-175, 1978.
-
(1978)
J. Pharmacokinet. Biopharm.
, vol.6
, pp. 165-175
-
-
Yamaoka, K.1
Nakagawa, T.2
Uno, T.3
-
15
-
-
0019974468
-
Noncompartmental determination of the steady-state volume of distribution for any mode of administration
-
Perrier, D., and Mayersohn, M. Noncompartmental determination of the steady-state volume of distribution for any mode of administration. J. Pharm. Sci., 71: 372-373, 1982.
-
(1982)
J. Pharm. Sci.
, vol.71
, pp. 372-373
-
-
Perrier, D.1
Mayersohn, M.2
-
16
-
-
12944252014
-
-
CI-994 Investigator's Brochure. Ann Arbor, MI: Parke-Davis Pharmaceutical Research, Division of Warner Lambert Co., 1994
-
CI-994 Investigator's Brochure. Ann Arbor, MI: Parke-Davis Pharmaceutical Research, Division of Warner Lambert Co., 1994.
-
-
-
-
17
-
-
12944250586
-
-
Los Angeles: Biomedical Simulations Resource, University of Southern California
-
D'Argenio, D., and Schumitzky, A. ADAPT II User's Guide, Vol. 9, pp. 115-134. Los Angeles: Biomedical Simulations Resource, University of Southern California, 1992.
-
(1992)
ADAPT II User's Guide
, vol.9
, pp. 115-134
-
-
D'Argenio, D.1
Schumitzky, A.2
-
18
-
-
12944275178
-
Cancer chemotherapy
-
D. Nathan and S. Orkin (eds.), Philadelphia: W. B. Saunders
-
Berg, S., Balis, F., and Poplack, D. Cancer chemotherapy. In: D. Nathan and S. Orkin (eds.), Nathan and Oski's Hematology of Infancy and Childhood, Vol. 2, pp. 1201-1232. Philadelphia: W. B. Saunders, 1998.
-
(1998)
Nathan and Oski's Hematology of Infancy and Childhood
, vol.2
, pp. 1201-1232
-
-
Berg, S.1
Balis, F.2
Poplack, D.3
|