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Volumn 14, Issue 4, 1996, Pages 349-356

Preclinical antitumor activity of CI-994

Author keywords

Acetyldinaline; CI 994; Preclinical antitumor activity

Indexed keywords

4 N ACETYLDINALINE; ANTINEOPLASTIC AGENT; BENZAMIDE DERIVATIVE; DINALINE; UNCLASSIFIED DRUG;

EID: 0030469421     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00180810     Document Type: Article
Times cited : (47)

References (26)
  • 2
    • 0022333546 scopus 로고
    • Synthesis, toxicity and therapeutic efficacy of 4-amino-N-(2′-aminophenyl) benzamide: A new compound preferentially active in slowly growing tumors
    • Berger MR, Bischoff H, Fritschi E, Henne T, Herrmann M, Pool BL, Satzinger G, Schmahl D, Weiershausen U: Synthesis, toxicity and therapeutic efficacy of 4-amino-N-(2′-aminophenyl) benzamide: a new compound preferentially active in slowly growing tumors. Cancer Treat Rep 69:1415-1424, 1985
    • (1985) Cancer Treat Rep , vol.69 , pp. 1415-1424
    • Berger, M.R.1    Bischoff, H.2    Fritschi, E.3    Henne, T.4    Herrmann, M.5    Pool, B.L.6    Satzinger, G.7    Schmahl, D.8    Weiershausen, U.9
  • 3
    • 0021984892 scopus 로고
    • Effectiveness of P-aminobenzoyl-O-phenylenediamine (GOE 1734) against mouse, rat and human tumor cells
    • Lelieveld P, Middeldorp RJF, Van Putten LM: Effectiveness of P-aminobenzoyl-O-phenylenediamine (GOE 1734) against mouse, rat and human tumor cells. Cancer Chemother Pharmacol 15:88-90, 1985
    • (1985) Cancer Chemother Pharmacol , vol.15 , pp. 88-90
    • Lelieveld, P.1    Middeldorp, R.J.F.2    Van Putten, L.M.3
  • 4
    • 0000055241 scopus 로고
    • Antineoplastic activity of two 4-amino-N-(2′-aminophenyl)benzamide (GOE 1734) derivatives in rat mammary carcinoma
    • Berger MR, Schmahl D: Antineoplastic activity of two 4-amino-N-(2′-aminophenyl)benzamide (GOE 1734) derivatives in rat mammary carcinoma. Proc Am Assoc Cancer Res 28:301, 1987
    • (1987) Proc Am Assoc Cancer Res , vol.28 , pp. 301
    • Berger, M.R.1    Schmahl, D.2
  • 6
    • 0004950066 scopus 로고
    • Activity and effects of 4-amino-N-(2-aminophenyl)benzamide (GOE 1734, PD 104208): A compound with a novel mechanism of action, against HCT-8
    • Kraker AJ, Moore CW: Activity and effects of 4-amino-N-(2-aminophenyl)benzamide (GOE 1734, PD 104208): a compound with a novel mechanism of action, against HCT-8. Proc Am Assoc Cancer Res 30:584, 1991
    • (1991) Proc Am Assoc Cancer Res , vol.30 , pp. 584
    • Kraker, A.J.1    Moore, C.W.2
  • 7
    • 0001605565 scopus 로고
    • Activity of biochemical properties of GOE 1734 (PD 104208), an anticancer agent with a novel mechanism of activity
    • Leopold WR, Hook KE, Fry DW: Activity of biochemical properties of GOE 1734 (PD 104208), an anticancer agent with a novel mechanism of activity. Proc Am Assoc Cancer Res 28:302, 1988
    • (1988) Proc Am Assoc Cancer Res , vol.28 , pp. 302
    • Leopold, W.R.1    Hook, K.E.2    Fry, D.W.3
  • 8
    • 0023885976 scopus 로고
    • Dinaline: A new oral drug against leukemia? Preclinical studies in a relevant rat model for human acute myelocytic leukemia (BNML)
    • Hagenbeek A, Weiershausen U, Martens ACM: Dinaline: a new oral drug against leukemia? Preclinical studies in a relevant rat model for human acute myelocytic leukemia (BNML). Leukemia (Baltimore) 2:226-230, 1988
    • (1988) Leukemia (Baltimore) , vol.2 , pp. 226-230
    • Hagenbeek, A.1    Weiershausen, U.2    Martens, A.C.M.3
  • 10
    • 0029099455 scopus 로고
    • Role of a small molecular weight phosphoprotein in the mechanism of action of CI-994 (N-acetyldinaline)
    • Rummel SA, Kraker AJ, Steinkampf RW, Hook KE, Klohs WD: Role of a small molecular weight phosphoprotein in the mechanism of action of CI-994 (N-acetyldinaline). Int J Cancer 62:636-642, 1995
    • (1995) Int J Cancer , vol.62 , pp. 636-642
    • Rummel, S.A.1    Kraker, A.J.2    Steinkampf, R.W.3    Hook, K.E.4    Klohs, W.D.5
  • 11
    • 26844449061 scopus 로고
    • Specific loss of a 16 kD phosphoprotein in colon tumor cells treated with the novel antitumor compound CI-994 [4-(acetylamino)-N-(2-aminophenyl)benzamide, N-acetyldinine]
    • Rummel S, Steinkampf R, Auerbach R, Kraker A, Klohs W: Specific loss of a 16 kD phosphoprotein in colon tumor cells treated with the novel antitumor compound CI-994 [4-(acetylamino)-N-(2-aminophenyl)benzamide, N-acetyldinine]. Proc Am Assoc Cancer Res 34:369, 1993
    • (1993) Proc Am Assoc Cancer Res , vol.34 , pp. 369
    • Rummel, S.1    Steinkampf, R.2    Auerbach, R.3    Kraker, A.4    Klohs, W.5
  • 12
    • 0000349250 scopus 로고
    • Mitochondrial involvement in the mechanism of action of the novel antitumor compound 4-(acetylamino)-N(2-aminophenyl)benzamide (PD-123654, GOE 5549)
    • Klohs W, Kraker A, Steinkampf R, Moore C, Dominick M: Mitochondrial involvement in the mechanism of action of the novel antitumor compound 4-(acetylamino)-N(2-aminophenyl)benzamide (PD-123654, GOE 5549). Proc Am Assoc Cancer Res 32:396, 1991
    • (1991) Proc Am Assoc Cancer Res , vol.32 , pp. 396
    • Klohs, W.1    Kraker, A.2    Steinkampf, R.3    Moore, C.4    Dominick, M.5
  • 13
    • 0000349250 scopus 로고
    • Cell cycle and nucleotide metabolism effects of 4-(acetylamino)-N-(2-aminophenyl) benzamide (PD 123654, GOE 5549) in HCT-8 cells
    • Kraker AJ, Wolven A, Fry DW, Klohs WD: Cell cycle and nucleotide metabolism effects of 4-(acetylamino)-N-(2-aminophenyl) benzamide (PD 123654, GOE 5549) in HCT-8 cells. Proc Am Assoc Cancer Res 32:396, 1991
    • (1991) Proc Am Assoc Cancer Res , vol.32 , pp. 396
    • Kraker, A.J.1    Wolven, A.2    Fry, D.W.3    Klohs, W.D.4
  • 14
    • 26844559347 scopus 로고
    • The role of protein phosphorylation in the mechanism of 4-(acetylamino)-N-(2-aminophenyl) benzamide (N-Acetyldinaline, CI-994)
    • Rummel SA, Steinkampf RW, Kraker AJ, Klohs WD: The role of protein phosphorylation in the mechanism of 4-(acetylamino)-N-(2-aminophenyl) benzamide (N-Acetyldinaline, CI-994). Proc Am Assoc Cancer Res 33:514, 1992
    • (1992) Proc Am Assoc Cancer Res , vol.33 , pp. 514
    • Rummel, S.A.1    Steinkampf, R.W.2    Kraker, A.J.3    Klohs, W.D.4
  • 16
    • 0016696542 scopus 로고
    • Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure
    • Corbett TH, Griswold DP Jr, Roberts BJ, Peckham JC, Schabel FM Jr: Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure. Cancer Res 35:2434-2439, 1975
    • (1975) Cancer Res , vol.35 , pp. 2434-2439
    • Corbett, T.H.1    Griswold Jr., D.P.2    Roberts, B.J.3    Peckham, J.C.4    Schabel Jr., F.M.5
  • 18
    • 0017707533 scopus 로고
    • Evaluation of single agents and combinations of chemotherapeutic agents in mouse colon carcinomas
    • Corbett TH, Griswold DP Jr, Roberts BJ, Peckham JC, Schabel FM Jr: Evaluation of single agents and combinations of chemotherapeutic agents in mouse colon carcinomas. Cancer 40:2660-2680, 1977
    • (1977) Cancer , vol.40 , pp. 2660-2680
    • Corbett, T.H.1    Griswold Jr., D.P.2    Roberts, B.J.3    Peckham, J.C.4    Schabel Jr., F.M.5
  • 19
    • 0019985097 scopus 로고
    • Response of transplantable tumors of mice to anthracenedione derivatives alone and in combination with clinically useful agents
    • Corbett TH, Roberts BJ, Trader MW Jr, Laster WR Jr, Griswold DP Jr, Schabel FM Jr: Response of transplantable tumors of mice to anthracenedione derivatives alone and in combination with clinically useful agents. Cancer Treat Rep 66(5):1187-1200, 1982
    • (1982) Cancer Treat Rep , vol.66 , Issue.5 , pp. 1187-1200
    • Corbett, T.H.1    Roberts, B.J.2    Trader Jr., M.W.3    Laster Jr., W.R.4    Griswold Jr., D.P.5    Schabel Jr., F.M.6
  • 20
    • 0018903599 scopus 로고
    • Surgical adjuvant chemotherapy of metastatic murine osteosarcoraa
    • Hiramoto RN, Ghanta VK: Surgical adjuvant chemotherapy of metastatic murine osteosarcoraa. Int J Cancer 25:393-397, 1980
    • (1980) Int J Cancer , vol.25 , pp. 393-397
    • Hiramoto, R.N.1    Ghanta, V.K.2
  • 21
    • 0002308228 scopus 로고
    • Discovery of solid tumor active agents using a soft-agar-colony-formation-disk-diffusion-assay
    • Valeriote FA, Corbett TH, Baker LH (eds), Norwell, Massachusetts: Kluwer Academic Publishers
    • Corbett TH, Valeriote FA, Polin L et al.: Discovery of solid tumor active agents using a soft-agar-colony-formation-disk-diffusion-assay. In: Valeriote FA, Corbett TH, Baker LH (eds), Cytotoxic Anticancer Drugs: Models and Concepts for Drug Discovery and Development, pp 35-87. Norwell, Massachusetts: Kluwer Academic Publishers, 1992
    • (1992) Cytotoxic Anticancer Drugs: Models and Concepts for Drug Discovery and Development , pp. 35-87
    • Corbett, T.H.1    Valeriote, F.A.2    Polin, L.3
  • 24
    • 2642602013 scopus 로고
    • Two-week oral toxicity study of CI-994 in rats
    • Graziano M, Walsh K: Two-week oral toxicity study of CI-994 in rats. Proc Am Assoc Cancer Res 35:460, 1994
    • (1994) Proc Am Assoc Cancer Res , vol.35 , pp. 460
    • Graziano, M.1    Walsh, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.