Nortriptyline versus fluoxetine in the treatment of depression and in short-term recovery after stroke: A placebo-controlled, double-blind study

American Journal of Psychiatry

Volumn 157, Issue 3, 2000, Pages 351-359

  Robinson, Robert G ^a   Schultz, Susan K ^b   Castillo, Carlos ^b   Kopel, Teresa ^b   Kosier, J Todd ^b   Newman, R Mark ^b   Curdue, Kathryn ^b   Petracca, Gustavo ^b   Starkstein, Sergio E ^b  

^a UNIVERSITY OF IOWA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; FLUOXETINE; NORTRIPTYLINE; PLACEBO; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; COGNITION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DAILY LIFE ACTIVITY; DEPRESSION; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NAUSEA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; STROKE; WEIGHT REDUCTION;

ACTIVITIES OF DAILY LIVING; ANTIDEPRESSIVE AGENTS, TRICYCLIC; CEREBROVASCULAR ACCIDENT; COGNITION DISORDERS; DEPRESSIVE DISORDER; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FLUOXETINE; HUMANS; NORTRIPTYLINE; PLACEBOS; PSYCHIATRIC STATUS RATING SCALES; SEROTONIN UPTAKE INHIBITORS; SOCIAL ADJUSTMENT; TREATMENT OUTCOME; WEIGHT LOSS;

EID: 0034058054     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/appi.ajp.157.3.351     Document Type: Article

References (28)

1. Lipsey JR, Robinson RG, Pearlson GD, Rao K, Price TR: Nortriptyline treatment of post-stroke depression: a double-blind treatment trial. Lancet 1984; 1:297-300
2. Reding JJ, Orto LA, Winter SW, Fortuna IM, DiPonte P, McDowell FH: Antidepressant therapy after stroke: a double-blind trial. Arch Neurol 1986; 43:763-765
3. Andersen G, Vestergaard K, Lauritzen L: Effective treatment of poststroke depression with the selective serotonin reuptake inhibitor citalopram. Stroke 1994; 25:1099-1104
4. Lauritzen L, Bendsen BB, Vilmar T, Bendsen EB, Lunde M, Bech P: Post-stroke depression: combined treatment with imipramine or desipramine and mianserin: a controlled clinical study. Psychopharmacology (Berl) 1994; 114:119-122
5. Tollefson GD, Bosomworth JC, Heiligenstein JH, Potvin JH, Holman S: A double-blind, placebo-controlled clinical trial of fluoxetine in geriatric patients with major depression. Int Psychogeriatr 1995; 7:89-104
6. Roose SP, Laghrissi-Thode F, Kennedy JS, Nelson JC, Bigger JT Jr, Pollock BG, Gaffney A, Narayan M, Finkel MS, McCafferty J, Gergel I: Comparison of paroxetine and nortriptyline in depressed patients with ischemic heart disease. JAMA 1998; 279:287-291
7. Brymer C, Winograd C: Fluoxetine in elderly patients: is there a cause for concern? J Am Geriatr 1992; 40:902-905
8. Roose SP, Glassman AH, Attia E, Woodring S: Comparative efficacy of selective serotonin reuptake inhibitors and tricyclics in the treatment of melancholia. Am J Psychiatry 1994; 151:1735-1739
9. DeRenzi E, Faglioni P: Development of a shortened version of the Token Test. Cortex 1978; 14:41-49
10. Robinson RG, Parikh RM, Lipsey JR, Starkstein SE, Price TR: Pathological laughing and crying following stroke: validation of measurement scale and a double-blind treatment study. Am J Psychiatry 1993; 150:286-293
11. Robinson RG, Starr LB, Kubos KL, Price TR: A two year Iongitudinal study of post-stroke mood disorders: findings during the initial evaluation. Stroke 1983; 14:736-744
12. Robinson RG, Szetela B: Mood change following left hemispheric brain injury. Ann Neurol 1981; 9:447-453
13. Starkstein SE, Fedoroff JP, Price TR, Leiguarda R, Robinson RG: Anosognosia in patients with cerebrovascular lesions: a study of causative factors. Stroke 1992; 23:1446-1453
14. Ottenbacher KJ, Mann WC, Granger CV, Tomita M, Hurren D, Charvat B: Inter-rater agreement and stability of functional assessment in the community-based elderly. Arch Phys Med Rehabil 1994; 75:1297-1301
15. Robinson RG, Kubos KL, Starr LB, Rao K, Price TR: Mood changes in stroke patients: relationship to lesion location. Compr Psychiatry 1983; 24:555-566
16. Folstein MF, Folstein SE, McHugh PR: "Mini-Mental State": a practical method of grading the cognitive state of patients for the clinician. J Psychiatry Res 1975; 12:189-198
17. Robinson RG, Bolla-Wilson K, Kaplan E, Lipsey JR, Price TR: Depression influences intellectual impairment in stroke patients. Br J Psychiatry 1986; 148:541-547
18. Robinson RG, Starr LB, Price TR: A two-year longitudinal study of post-stroke mood disorders: dynamic changes in associated variables over the first six months of follow-up. Stroke 1984; 15:510-517
19. Starr LB, Robinson RG, Price TR: The Social Functioning Exam: an assessment of stroke patients. Soc Work Res Abstr 1983; 18:28-33
20. Robinson RG, Bolduc PL, Kubos KL, Starr LB, Price TR: Social functioning assessment in stroke patients. Arch Phys Med Rehabil 1985; 66:496-500
21. Cliff N: Ordinal Methods for Behavioral Data Analysis. Mahway, NJ, Lawrence Erlbaum Associates, 1996
22. Conover WJ, Iman RL: Rank transformations as a bridge between parametric and nonparametric statistics. Am Statistician 1981; 35:124-129
23. Ackerman DL, Greenland S, Bystritsky A, Small GU: Characteristics of fluoxetine versus placebo responders in a randomized trial of geriatric depression. Psychopharmacol Bull 1997; 33:707-714
24. Evans M, Hammond M, Wilson K, Lye M, Copeland J: Placebo controlled treatment trial of depression in elderly physically ill patients, Int J Geriatr Psychiatry 1997; 12:817-824
25. Goldstein DJ, Hamilton SH, Masica DN, Beasley CM Jr: Fluoxetine in medically stable, depressed geriatric patients: effects on weight. J Clin Psychopharmacol 1997; 17:365-369
26. Schneider LS, Small GW, Hamilton SH, Bystritsky A, Nemeroff CB, Meyers BS: Estrogen replacement and response to fluoxetine in a multicenter geriatric depression trial. Am J Geriatr Psychiatry 1997; 5:97-106
27. Gonzalez-Torrecillas JL, Mendlewicz J, Lobo A: Repercussion of early treatment of post-stroke depression on neuropsychological rehabilitation. Int Psychogeriatr 1995; 7:547-560
28. Crisostomo EA, Duncan PW, Propst M, Dawson D, Davis JN: Evidence that amphetamine with physical therapy promotes recovery of motor function in stroke patients. Ann Neurol 1988; 23:94-97