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Volumn 30, Issue 5, 2000, Pages 438-446

rhIGF-I/IGFBP-3 complex, but not free rhIGF-I, supports muscle protein biosynthesis in rats during semistarvation

Author keywords

4E binding protein 1; Eucaryotic initiation factor 4E; Messenger RNA; Nutrition; Protein synthesis

Indexed keywords

INITIATION FACTOR; INSULIN; MESSENGER RNA; MUSCLE PROTEIN; PHENYLALANINE; RECOMBINANT SOMATOMEDIN C; SOMATOMEDIN BINDING PROTEIN 3;

EID: 0034057544     PISSN: 00142972     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2362.2000.00652.x     Document Type: Article
Times cited : (34)

References (46)
  • 1
    • 0020537642 scopus 로고
    • Metabolic response of whole body and peripheral tissues to enteral nutrition in weight-losing cancer and noncancer patients
    • 1 Bennegard K, Eden E, Ekman L, Schersten T, Lundholm K. Metabolic response of whole body and peripheral tissues to enteral nutrition in weight-losing cancer and noncancer patients. Gastroenterology 1983;85 (1):92-9.
    • (1983) Gastroenterology , vol.85 , Issue.1 , pp. 92-99
    • Bennegard, K.1    Eden, E.2    Ekman, L.3    Schersten, T.4    Lundholm, K.5
  • 2
    • 0026084963 scopus 로고
    • Effect on whole-body protein synthesis after institution of intravenous nutrition in cancer and non-cancer patients who lose weight
    • 2 Hyltander A, Warnold I, Eden E, Lundholm K. Effect on whole-body protein synthesis after institution of intravenous nutrition in cancer and non-cancer patients who lose weight [see comments]. Eur J Cancer 1991;27 (1):16-21.
    • (1991) Eur J Cancer , vol.27 , Issue.1 , pp. 16-21
    • Hyltander, A.1    Warnold, I.2    Eden, E.3    Lundholm, K.4
  • 3
    • 0025831048 scopus 로고
    • Insufficient effect of total parenteral nutrition to improve protein balance in peripheral tissues of surgical patients
    • 3 Moller-Loswick AC, Zachrisson H, Bennegard K, Sandstrom R, Lundholm K. Insufficient effect of total parenteral nutrition to improve protein balance in peripheral tissues of surgical patients. JPEN J Parenter Enteral Nutr 1991;15 (6):669-75.
    • (1991) JPEN J Parenter Enteral Nutr , vol.15 , Issue.6 , pp. 669-675
    • Moller-Loswick, A.C.1    Zachrisson, H.2    Bennegard, K.3    Sandstrom, R.4    Lundholm, K.5
  • 4
    • 0027405908 scopus 로고
    • Growth factors in nutritional support
    • 4 Hatton J, Luer MS, Rapp RP. Growth factors in nutritional support. Pharmacotherapy 1993;13 (1):17-27.
    • (1993) Pharmacotherapy , vol.13 , Issue.1 , pp. 17-27
    • Hatton, J.1    Luer, M.S.2    Rapp, R.P.3
  • 5
    • 0019022878 scopus 로고
    • Lilly lecture 1979 role of insulin in the regulation of protein synthesis
    • 5 Jefferson LS. Lilly Lecture 1979 role of insulin in the regulation of protein synthesis. Diabetes 1980;29 (6):487-96.
    • (1980) Diabetes , vol.29 , Issue.6 , pp. 487-496
    • Jefferson, L.S.1
  • 7
    • 0023196951 scopus 로고
    • Effect of physiologic hyperinsulinemia on skeletal muscle protein synthesis and breakdown in man
    • 7 Gelfand RA, Barrett EJ. Effect of physiologic hyperinsulinemia on skeletal muscle protein synthesis and breakdown in man. J Clin Invest 1987;80 (1):1-6.
    • (1987) J Clin Invest , vol.80 , Issue.1 , pp. 1-6
    • Gelfand, R.A.1    Barrett, E.J.2
  • 8
    • 0022475294 scopus 로고
    • Insulin decreases muscle protein loss after operative trauma in man
    • 8 Inculet RI, Finley RJ, Duff JH, Pace R, Rose C, Groves AC et al. Insulin decreases muscle protein loss after operative trauma in man. Surgery 1986;99 (6):752-8.
    • (1986) Surgery , vol.99 , Issue.6 , pp. 752-758
    • Inculet, R.I.1    Finley, R.J.2    Duff, J.H.3    Pace, R.4    Rose, C.5    Groves, A.C.6
  • 10
    • 0027103153 scopus 로고
    • Role of insulin-like growth factors and growth hormone in reversing catabolic states
    • 10 Clemmons DR, Underwood LE. Role of insulin-like growth factors and growth hormone in reversing catabolic states. Horm Res 1992;38 (Suppl. 2):37-40.
    • (1992) Horm Res , vol.38 , Issue.SUPPL. 2 , pp. 37-40
    • Clemmons, D.R.1    Underwood, L.E.2
  • 11
    • 0027533214 scopus 로고
    • Enhancement of the anabolic effects of growth hormone and insulin-like growth factor I by use of both agents simultaneously
    • 11 Kupfer SR, Underwood LE, Baxter RC, Clemmons DR. Enhancement of the anabolic effects of growth hormone and insulin-like growth factor I by use of both agents simultaneously. J Clin Invest 1993;91 (2):391-6.
    • (1993) J Clin Invest , vol.91 , Issue.2 , pp. 391-396
    • Kupfer, S.R.1    Underwood, L.E.2    Baxter, R.C.3    Clemmons, D.R.4
  • 12
    • 0025915444 scopus 로고
    • The effects of infusion of insulinlike growth factor (IGF) I, IGF-II, and insulin on glucose and protein metabolism in fasted lambs
    • 12 Douglas RG, Gluckman PD, Ball K, Breier B, Shaw JH. The effects of infusion of insulinlike growth factor (IGF) I, IGF-II, and insulin on glucose and protein metabolism in fasted lambs. J Clin Invest 1991;88 (2):614-22.
    • (1991) J Clin Invest , vol.88 , Issue.2 , pp. 614-622
    • Douglas, R.G.1    Gluckman, P.D.2    Ball, K.3    Breier, B.4    Shaw, J.H.5
  • 13
    • 0028858574 scopus 로고
    • The effect of recombinant human IGF-I on protein metabolism in post-operative patients without nutrition compared to effects in experimental animals
    • 13 Sandstrom R, Svanberg E, Hyltander A, Haglind E, Ohlsson C, Zachrisson H et al. The effect of recombinant human IGF-I on protein metabolism in post-operative patients without nutrition compared to effects in experimental animals. Eur J Clin Invest 1995;25 (10):784-92.
    • (1995) Eur J Clin Invest , vol.25 , Issue.10 , pp. 784-792
    • Sandstrom, R.1    Svanberg, E.2    Hyltander, A.3    Haglind, E.4    Ohlsson, C.5    Zachrisson, H.6
  • 14
    • 0025836055 scopus 로고
    • The induction of a specific protease for insulin-like growth factor binding protein-3 in the circulation during severe illness
    • 14 Davies SC, Wass JA, Ross RJ, Cotterill AM, Buchanan CR, Coulson VJ et al. The induction of a specific protease for insulin-like growth factor binding protein-3 in the circulation during severe illness. J Endocrinol 1991;130 (3):469-73.
    • (1991) J Endocrinol , vol.130 , Issue.3 , pp. 469-473
    • Davies, S.C.1    Wass, J.A.2    Ross, R.J.3    Cotterill, A.M.4    Buchanan, C.R.5    Coulson, V.J.6
  • 16
    • 0029155620 scopus 로고
    • Systemic administration of rhIGF-I or rhIGF-I/ IGFBP-3 increases cortical bone and lean body mass in ovariectomized rats
    • 16 Bagi CM, DeLeon E, Brommage R, Adams S, Rosen D, Sommer A. Systemic administration of rhIGF-I or rhIGF-I/ IGFBP-3 increases cortical bone and lean body mass in ovariectomized rats. Bone 1995;16 (4 Suppl.):263S-269S.
    • (1995) Bone , vol.16 , Issue.4 SUPPL.
    • Bagi, C.M.1    DeLeon, E.2    Brommage, R.3    Adams, S.4    Rosen, D.5    Sommer, A.6
  • 17
    • 0019491372 scopus 로고    scopus 로고
    • Evaluation of anorexia as the cause of altered protein synthesis in skeletal muscles from nongrowing mice with sarcoma
    • 17 Lundholm K, Karlberg I, Ekman L, Trom S, Schersten T. Evaluation of anorexia as the cause of altered protein synthesis in skeletal muscles from nongrowing mice with sarcoma. Cancer Res 1998;41 (5):1989-96.
    • (1998) Cancer Res , vol.41 , Issue.5 , pp. 1989-1996
    • Lundholm, K.1    Karlberg, I.2    Ekman, L.3    Trom, S.4    Schersten, T.5
  • 18
    • 0029989622 scopus 로고    scopus 로고
    • Insulin and diabetes cause reciprocal changes in the association of eIF-4E and PHASE-I in rat skeletal muscle
    • 2 Pt 1
    • 18 Kimball SR, Jefferson LS, Fadden P, Haystead TA, Lawrence JC Jr. Insulin and diabetes cause reciprocal changes in the association of eIF-4E and PHAS-I in rat skeletal muscle. Am J Physiol 1996;270 (2 Pt 1):C705-9.
    • (1996) Am J Physiol , vol.270
    • Kimball, S.R.1    Jefferson, L.S.2    Fadden, P.3    Haystead, T.A.4    Lawrence J.C., Jr.5
  • 19
    • 0028032605 scopus 로고
    • Purification and characterization of eukaryotic translational initiation factor eIF-2B from liver
    • 19 Kimball SR, Karinch AM, Feldhoff RC, Mellor H, Jefferson LS. Purification and characterization of eukaryotic translational initiation factor eIF-2B from liver. Biochim Biophys Acta 1994;1201:473-81.
    • (1994) Biochim Biophys Acta , vol.1201 , pp. 473-481
    • Kimball, S.R.1    Karinch, A.M.2    Feldhoff, R.C.3    Mellor, H.4    Jefferson, L.S.5
  • 20
    • 0006789567 scopus 로고
    • Regulation of insulin-like growth factor I gene expression by growth hormone
    • 20 Mathews LS, Norstedt G, Palmiter RD. Regulation of insulin-like growth factor I gene expression by growth hormone. Proc Natl Acad Sci USA 1986;83 (24):9343-7.
    • (1986) Proc Natl Acad Sci USA , vol.83 , Issue.24 , pp. 9343-9347
    • Mathews, L.S.1    Norstedt, G.2    Palmiter, R.D.3
  • 21
    • 0025952626 scopus 로고
    • Quantitative comparison of insulin-like growth factor mRNA levels in human and rat tissues analysed by a solution hybridization assay
    • 21 Moller C, Arner P, Sonnenfeld T, Norstedt G. Quantitative comparison of insulin-like growth factor mRNA levels in human and rat tissues analysed by a solution hybridization assay. J Mol Endocrinol 1991;7 (3):213-22.
    • (1991) J Mol Endocrinol , vol.7 , Issue.3 , pp. 213-222
    • Moller, C.1    Arner, P.2    Sonnenfeld, T.3    Norstedt, G.4
  • 23
    • 0013639839 scopus 로고
    • Regulation of rat growth hormone receptor gene expression
    • Oct 86
    • 23 Mathews LS, Enberg B, Norstedt G. Regulation of rat growth hormone receptor gene expression. Proc Natl Acad Sci 1989;19 (Oct 86):7451-5.
    • (1989) Proc Natl Acad Sci , vol.19 , pp. 7451-7455
    • Mathews, L.S.1    Enberg, B.2    Norstedt, G.3
  • 24
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • 24 Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162 (1):156-9.
    • (1987) Anal Biochem , vol.162 , Issue.1 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 25
    • 0020773108 scopus 로고
    • Practical approach for quantitating specific mRNAs by solution hybridization
    • 25 Durnam DM, Palmiter RDA. practical approach for quantitating specific mRNAs by solution hybridization. Anal Biochem 1983;131 (2):385-93.
    • (1983) Anal Biochem , vol.131 , Issue.2 , pp. 385-393
    • Durnam, D.M.1    Palmiter, R.D.A.2
  • 26
    • 0018850985 scopus 로고
    • Simple, rapid, and sensitive DNA assay procedure
    • 26 Labarca C, Paigen KA. simple, rapid, and sensitive DNA assay procedure. Anal Biochem 1980;102 (2):344-52.
    • (1980) Anal Biochem , vol.102 , Issue.2 , pp. 344-352
    • Labarca, C.1    Paigen, K.A.2
  • 27
    • 0028379864 scopus 로고
    • Radioimmunoassays for IGFs and IGFBPs
    • 27 Blum WF, Breier BH. Radioimmunoassays for IGFs and IGFBPs. Growth Regul 1994;4 (Suppl. 1):11-9.
    • (1994) Growth Regul , vol.4 , Issue.SUPPL. 1 , pp. 11-19
    • Blum, W.F.1    Breier, B.H.2
  • 28
    • 12644253855 scopus 로고    scopus 로고
    • Insulin-like growth factor I inhibits degradation and improves retention of protein in hindlimb muscle of lambs
    • 6 Pt 1
    • 28 Oddy VH, Owens PC. Insulin-like growth factor I inhibits degradation and improves retention of protein in hindlimb muscle of lambs. Am J Physiol 1996;271 (6 Pt 1):E973-82.
    • (1996) Am J Physiol , vol.271
    • Oddy, V.H.1    Owens, P.C.2
  • 29
    • 0029881462 scopus 로고    scopus 로고
    • Role of insulin and IGF-I in activation of muscle protein synthesis after oral feeding
    • 4 Pt 1
    • 29 Svanberg E, Zachrisson H, Ohlsson C, Iresjo BM, Lundholm KG. Role of insulin and IGF-I in activation of muscle protein synthesis after oral feeding. Am J Physiol 1996;270 (4 Pt 1):E614-20.
    • (1996) Am J Physiol , vol.270
    • Svanberg, E.1    Zachrisson, H.2    Ohlsson, C.3    Iresjo, B.M.4    Lundholm, K.G.5
  • 30
    • 0028014548 scopus 로고
    • Nutritional regulation of hormones and growth factors that control mammalian growth
    • 30 Straus DS. Nutritional regulation of hormones and growth factors that control mammalian growth. Faseb J 1994;8 (1):6-12.
    • (1994) Faseb J , vol.8 , Issue.1 , pp. 6-12
    • Straus, D.S.1
  • 31
    • 0026673704 scopus 로고
    • In-vivo regulation of messenger RNA encoding insulin-like growth factor-I (IGF-I) and its receptor by diabetes, insulin and IGF-I in rat muscle
    • 31 Bornfeldt KE, Skottner A, Arnqvist HJ. In-vivo regulation of messenger RNA encoding insulin-like growth factor-I (IGF-I) and its receptor by diabetes, insulin and IGF-I in rat muscle. J Endocrinol 1992;135:203-11.
    • (1992) J Endocrinol , vol.135 , pp. 203-211
    • Bornfeldt, K.E.1    Skottner, A.2    Arnqvist, H.J.3
  • 32
    • 0024382014 scopus 로고
    • Regulation by fasting of rat insulin-like growth factor I and its receptor. Effects on gene expression and binding
    • 32 Lowe WL Jr, Adamo M, Werner H, Roberts CT Jr, LeRoith D. Regulation by fasting of rat insulin-like growth factor I and its receptor. Effects on gene expression and binding. J Clin Invest 1989 84 (2):619-26.
    • (1989) J Clin Invest , vol.84 , Issue.2 , pp. 619-626
    • Lowe W.L., Jr.1    Adamo, M.2    Werner, H.3    Roberts C.T., Jr.4    LeRoith, D.5
  • 34
    • 0019495527 scopus 로고
    • The effect of fasting on liver receptors for prolactin and growth hormone
    • 34 Baxter RC, Bryson JM, Turtle JR. The effect of fasting on liver receptors for prolactin and growth hormone. Metabolism 1981;30 (11):1086-90.
    • (1981) Metabolism , vol.30 , Issue.11 , pp. 1086-1090
    • Baxter, R.C.1    Bryson, J.M.2    Turtle, J.R.3
  • 35
    • 0025129073 scopus 로고
    • Effect of fasting on insulin-like growth factor-I (IGF-I) and growth hormone receptor mRNA levels and IGF-I gene transcription in rat liver
    • 35 Straus DS, Takemoto CD. Effect of fasting on insulin-like growth factor-I (IGF-I) and growth hormone receptor mRNA levels and IGF-I gene transcription in rat liver. Mol Endocrinol 1990;4 (1):91-100.
    • (1990) Mol Endocrinol , vol.4 , Issue.1 , pp. 91-100
    • Straus, D.S.1    Takemoto, C.D.2
  • 36
    • 0030003211 scopus 로고    scopus 로고
    • Protein synthesis in skeletal muscle and jejunum is more responsive to feeding in 7-than in 26-day-old pigs
    • 5 Pt 1
    • 36 Davis TA, Burrin DG, Fiorotto ML, Nguyen HV. Protein synthesis in skeletal muscle and jejunum is more responsive to feeding in 7-than in 26-day-old pigs. Am J Physiol 1996;270 (5 Pt 1):E802-9.
    • (1996) Am J Physiol , vol.270
    • Davis, T.A.1    Burrin, D.G.2    Fiorotto, M.L.3    Nguyen, H.V.4
  • 37
    • 0028178928 scopus 로고
    • PDGF- and insulin-dependent pp. 70S6k activation mediated by phosphatidylinositol-3-OH kinase
    • 37 Chung J, Grammer TC, Lemon KP, Kazlauskas A, Blenis J. PDGF-and insulin-dependent pp. 70S6k activation mediated by phosphatidylinositol-3-OH kinase. Nature 1994;370 (6484):71-5.
    • (1994) Nature , vol.370 , Issue.6484 , pp. 71-75
    • Chung, J.1    Grammer, T.C.2    Lemon, K.P.3    Kazlauskas, A.4    Blenis, J.5
  • 38
    • 0030973515 scopus 로고    scopus 로고
    • Postprandial stimulation of muscle protein synthesis is independent of changes in insulin
    • 5 Pt 1
    • 38 Svanberg E, Jefferson LS, Lundholm K, Kimball SR. Postprandial stimulation of muscle protein synthesis is independent of changes in insulin. Am J Physiol 1997;272 (5 Pt 1):E841-7.
    • (1997) Am J Physiol , vol.272
    • Svanberg, E.1    Jefferson, L.S.2    Lundholm, K.3    Kimball, S.R.4
  • 39
    • 0028308412 scopus 로고
    • Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70, S6 kinase, DNA synthesis, and glucose transporter translocation
    • 39 Cheatham B, Vlahos CJ, Cheatham L, Wang L, Blenis J, Kahn CR. Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70, S6 kinase, DNA synthesis, and glucose transporter translocation. Mol Cell Biol 1994;14 (7):4902-11.
    • (1994) Mol Cell Biol , vol.14 , Issue.7 , pp. 4902-4911
    • Cheatham, B.1    Vlahos, C.J.2    Cheatham, L.3    Wang, L.4    Blenis, J.5    Kahn, C.R.6
  • 40
    • 0018139377 scopus 로고
    • Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice
    • 40 Coleman DL. Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 1978;14 (3):141-8.
    • (1978) Diabetologia , vol.14 , Issue.3 , pp. 141-148
    • Coleman, D.L.1
  • 41
    • 0029964974 scopus 로고    scopus 로고
    • The role of eIF4 in cell proliferation
    • 41 Flynn A, Proud CG. The role of eIF4 in cell proliferation. Cancer Surv 1996;27:293-310.
    • (1996) Cancer Surv , vol.27 , pp. 293-310
    • Flynn, A.1    Proud, C.G.2
  • 42
    • 0029435015 scopus 로고
    • Pharmacokinetics and bioavailability of rhIGF-I/IGFBP-3 in the rat and monkey
    • 42 Adams S, Moore J, Chu S, Bagi C, DeLeon L, Liu C et al. Pharmacokinetics and bioavailability of rhIGF-I/IGFBP-3 in the rat and monkey. Prog Growth Factor Res 1995;6 (2-4):347-56.
    • (1995) Prog Growth Factor Res , vol.6 , Issue.2-4 , pp. 347-356
    • Adams, S.1    Moore, J.2    Chu, S.3    Bagi, C.4    DeLeon, L.5    Liu, C.6
  • 43
    • 0000140111 scopus 로고    scopus 로고
    • Musculoskeletal effects of recombinant human insulin-like growth factor-I (rhIGF-I) / IGF binding protein-3 (IGFBP-3) in hip fracture patients: Results from a double blind placebo-controlled phase II study
    • 43 Geusens P, Bouillon R, Broos P, Rosen D, Adams S, Sanders M et al. Musculoskeletal effects of recombinant human insulin-like growth factor-I (rhIGF-I) / IGF binding protein-3 (IGFBP-3) in hip fracture patients: results from a double blind placebo-controlled phase II study. Bone 1998;23 (Suppl.): S157.
    • (1998) Bone , vol.23 , Issue.SUPPL.
    • Geusens, P.1    Bouillon, R.2    Broos, P.3    Rosen, D.4    Adams, S.5    Sanders, M.6
  • 44
    • 0017999338 scopus 로고
    • Effect of starvation on initiation of protein synthesis in skeletal muscle and heart
    • 44 Rannels DE, Pegg AE, Rannels SR, Jefferson LS. Effect of starvation on initiation of protein synthesis in skeletal muscle and heart. Am J Physiol 1978;235 (2):E126-33.
    • (1978) Am J Physiol , vol.235 , Issue.2
    • Rannels, D.E.1    Pegg, A.E.2    Rannels, S.R.3    Jefferson, L.S.4
  • 46
    • 0031730932 scopus 로고    scopus 로고
    • Effect of dietary protein on translation initiation in rat skeletal muscle and liver
    • 5 Pt 1
    • 46 Yoshizawa F, Kimball SR, Vary TC, Jefferson LS. Effect of dietary protein on translation initiation in rat skeletal muscle and liver. Am J Physiol 1998;275 (5 Pt 1):E814-20.
    • (1998) Am J Physiol , vol.275
    • Yoshizawa, F.1    Kimball, S.R.2    Vary, T.C.3    Jefferson, L.S.4


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