Insulin-like growth factor I inhibits degradation and improves retention of protein in hindlimb muscle of lambs

American Journal of Physiology - Endocrinology and Metabolism

Volumn 271, Issue 6 34-6, 1996, Pages

  Hutton Oddy, V ^a,c   Owens, Phillip C ^b  

^a NSW DEPARTMENT OF PRIMARY INDUSTRIES   (Australia)

^b CSIRO   (Australia)

^c UNIVERSITY OF NEW ENGLAND   (Australia)

Author keywords

glucose uptake; insulin; insulin like growth factor binding proteins; oxygen uptake

Indexed keywords

SOMATOMEDIN C;

ANIMAL TISSUE; ARTICLE; GLUCOSE TRANSPORT; LAMB; LEG MUSCLE; MUSCLE METABOLISM; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN DEGRADATION;

EID: 12644253855     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1996.271.6.e973     Document Type: Article

References (42)

1. Barrett, E. J., J. H. Revkin, L. H. Young, B. L. Zaret, F. Jacob, and R. A. Gelfand. An isotopic method for measurement of muscle protein synthesis and degradation in vivo. Biochem. J. 245: 223-228, 1987.
2. Bucuvalas, J. C., W. Cutfield, J. Horn, M. A. Sperling, J. E. Heubi, B. Campaigne, and S. D. Chernausek. Resistance to the growth-promoting and metabolic effects of growth hormone in children with chronic liver disease. J. Pediatr. 117: 397-402, 1990.
3. Carr, J. M., J. A. Owens, P. A. Grant, P. E. Walton, P. C. Owens, and J. C. Wallace. Circulating insulin-like growth factors (IGFs), IGF-bindingproteins (IGFBPs) and tissue mRNA levels of IGFBP-2 and IGFBP-4 in the ovine fetus. J. Endocrinol. 145: 545-557, 1995.
4. Cottam, Y. H., H. T. Blair, B. W. Gallaher, R. W. Purchas, B. H. Breier, S. N. McCutcheon, and P. D. Gluckman. Body growth, carcass composition, and endocrine changes in lambs chronically treated with recombinantly derived insulin like growth factor-1. Endocrinology 130: 2924-2930, 1992.
5. Daughaday, W. H., K. A. Parker, S. Dorowsky, B. Trivedi, and M. Kapadia. Measurement of somatomedin-related peptides in fetal, neonatal and maternal rat serum by insulin-like growth factor (IGF) I radioimmunoassay, IGF-II radioreceptor assay (RRA) and multiplication-stimulating activity RRA after acid-ethanol extraction. Endocrinology 110: 575-581, 1982.
6. Douglas, R. G., P. D. Gluckman, K. Ball, B. Breier, and J. H. F. Shaw. The effects of insulin-like growth factor (IGF)I, IGF-II, and insulin on glucose and protein metabolism in fasted lambs. J. Clin. Invest. 88: 614-622, 1991.
7. Fogarty, N. M. Increased ewe reproduction: 200% lambs. Proc. Aust. Soc. Anim. Prod. 15: 61-79, 1984.
8. Francis, G. L., K. A. McNeil, J. C. Wallace, F. J. Ballard, and P. C. Owens. Sheep insulin-like growth factors I and II: sequences, activities and assays. Endocrinology 124: 1173-1183, 1989.
9. Gilmour, A. R. REG - a generalised linear models program. Department of Agriculture, NSW, 1988. (Misc. Bull. 1)
10. Guler, H.-P., J. Zapf, and E. R. Froesch. Short-term metabolic effects of recombinant human insulin-like growth factor I in healthy adults. N. Eng. J. Med. 317: 137-140, 1987.
11. Hizuka, N., K. Takano, K. Shizume, K. Asakawa, M. Miyakawa, I. Tanaka, and R. Horikawa. Insulin-like growth factor I stimulates growth of normal growing rats. Eur. J. Pharmacol. 125: 143-146, 1986.
12. Holly, J. M. P., S. A. Aimie, R. R. Sandhu, L. H. Rees, and J. A. H. Wass. The role of growth hormone in diabetes mellitus. J. Endocrinol. 118: 353-364, 1988.
13. Horn, S., M. D. R. Stern, M. Young, and D. E. Noakes. Influence of insulin and substrate concentration on protein synthetic rate in fetal tissues. Res. Vet. Sci. 35: 35-41, 1983.
14. Hossenlopp, P., D. Seurin, B. Segovia-Quinson, S. Hardouin, and M. Binoux. Analysis of serum insulin-like growth factor binding proteins using Western blotting: use of the method for titration of the binding proteins and competitive binding studies. Anal. Biochem. 154: 138-143, 1986.
15. Isley, W. L., L. E. Underwood, and D. R. Clemmons. Dietary components that regulate serum somatomedin-C concentrations in humans. J. Clin. Invest. 71: 175-182, 1983.
16. Johnson, R. J., J. P. McMurtry, and F. J. Ballard. Ontogeny and secretory patterns of plasma insulin-like growth factor-1 concentrations in meat-type chickens. J. Endocrinol. 124: 81-87, 1989.
17. Jones, I. R., and D. R. Clemmons. Insulin-like growth factors and their binding proteins: biological actions. Endocr. Rev. 16: 3-34, 1995.
18. Kelley, F. Improved method for microtitration of fatty acids. Anal. Chem. 37: 1078-1079, 1965.
19. Kind, K. L., J. A. Owens, J. S. Robinson, K. J. Quinn, P. A. Grant, P. E. Walton, R. S. Gilmour, and P. C. Owens. Effect of restriction of placental growth on the expression of IGFs in fetal sheep: relationship to fetal growth, circulating IGFs and binding proteins. J. Endocrinol. 146: 23-34, 1995.
20. Lee, H. M., M. D. Forde, M. C. Lee, and D. J. Bucher. Fluorometric microbore amino acid analyser. The construction of an inexpensive, highly sensitive instrument using o-phthaldehyde as detection agent. Anal. Biochem. 96: 298-307, 1979.
21. Lemmey, A. B., A. E. Martin, L. C. Read, F. M. Tomas, P. C. Owens, and F. J. Ballard. IGF-I and the truncated analogue des-(1-3)IGF-I enhance growth in rats after gut resection. Am. J. Physiol 260 (Endocrinol. Metab. 23): E213-E219, 1991.
22. Lewitt, M. S., H. Saunders, G. J. Cooney, and R. C. Baxter. Effect of human insulin-like growth factor-binding protein-1 on the half-life and action of administered insulin-like growth factor-1 in rats. J. Endocrinol. 136: 253-260, 1993.
23. Lobley, G. E., P. M. Harris, P. A. Skene, D. Brown, E. Milne, A. G. Calder, S. E. Anderson, P. J. Garlick, I. Nevison, and A. Connell. Responses in tissue protein synthesis to sub- and supra-maintenance intake in ruminant lambs: comparison of large dose and continuous infusion techniques. Br. J. Nutr. 68: 373-388, 1992.
24. Lord, A. P. D., L. C. Read, P. C. Owens, A. A. Martin, P. E. Walton, and F. J. Ballard. Rapid changes in plasma concentrations of insulin-like growth factor I (IGF-1) and IGF-II and IGF-binding proteins during anaesthesia in young sheep. J. Endocrinol. 141: 427-437, 1994.
25. Mauras, N., F. Z. Horber, and M. W. Haymond. Low dose recombinant human insulin-like growth factor-1 fails to affect protein anabolism but inhibits islet cell secretion in humans. J. Clin. Endocrinol. Metab. 75: 1192-1197, 1992.
26. Oddy, V. H., B. W. Brown, and A. W. Jones. Measurement of organ blood flow using tritiated water. I. Hind limb blood flow in conscious ewes. Aust. J. Biol. Sci. 43: 419-425, 1981.
27. Oddy, V. H., A. W. Jones, and H. M. Warren. Phenylalanine as a marker of muscle protein synthesis (Abstract). Proc. Nutr. Soc. Aust. 13: 119, 1988.
28. Oddy, V. H., and D. B. Lindsay. Determination of rates of protein synthesis, gain and degradation in intact hind-limb muscle of lambs. Biochem. J. 233: 417-425, 1986.
29. Oddy, V. H., and D. B. Lindsay. The contribution of protein synthesis to oxygen consumption in hind limb muscle of lambs (Abstract). Proc. Nutr. Soc. Aust. 12: 172, 1987.
30. Oddy, V. H., D. B. Lindsay, P. J. Barker, and A. J. Northrop. Effect of insulin on hind-limb and whole-body leucine and protein metabolism in fed and fasted lambs. Br. J. Nutr. 58: 437-452, 1987.
31. Owens, P. C., B. J. Johnson, R. G. Campbell, and F. J. Ballard. Growth hormone increases insulin-like growth factor-I (IGF-I) and decreases IGF-II in plasma of growing pigs. J. Endocrinol. 124: 269-275, 1990.
32. Rotwein, P. Structure, evolution, expression and regulation of insulin-like growth factors I and II. Growth Factors 5: 3-18, 1991.
33. Schoenle, E., J. Zapf, and E. R. Froesch. Insulin-like growth factor I stimulates growth in hypophysectomized rats. Nature Lond. 296: 252-253, 1982.
34. Shutt, D. A., H. Oddy, F. Bertus, and C. Ewoldt. Response of plasma IGF-1 and tissue receptors for insulin and IGF-1 to level of milk intake in lambs (Abstract). Proc. Endocr. Soc. Aust. 34: 47, 1991.
35. Somogyi, M. Determination of blood sugar. J. Biol. Chem. 160: 69-73, 1945.
36. Suikkari, A.-M., V. A. Koivisto, E.-M. Rutanen, H. Yki-Jarvinen, S.-L. Karonen, and M. Seppala. Insulin regulates serum levels of low molecular weight insulin-like growth factor binding protein. J. Clin. Endocrinol. Metab. 66: 266-272, 1988.
37. Teleni, E., and E. F. Annison. Development of a sheep hind-limb muscle preparation for metabolic studies. Aust. J. Biol. Sci. 39: 271-281, 1986.
38. Tomas, F. M., S. E. Knowles, P. C. Owens, C. S. Chandler, G. L. Francis, L. C. Read, and F. J. Ballard. Insulin-like growth factor-I (IGF-I) and especially IGF-I variants are anabolic in dexamethasone-treated rats. Biochem. J. 282: 91-97, 1992.
39. Tomas, F. M., S. E. Knowles, P. C. Owens, L. C. Read, C. S. Chandler, S. E. Garbosky, and F. J. Ballard. Effects of full-length and truncated insulin-like growth factor-I on nitrogen balance and muscle protein metabolism in nitrogen-restricted rats. J. Endocrinol. 128: 97-105, 1991.
40. Tomas, F. M., S. E. Knowles, P. C. Owens, L. C. Read, C. S. Chandler, S. E. Garbosky, and F. J. Ballard. Increased weight gain, nitrogen retention and muscle protein synthesis following treatment of diabetic rats with insulin-like growth factor (IGF)-I and des(1 - 3)IGF-I. Biochem. J. 276: 547-554, 1991.
41. Yang, H., D. S. Schalch, and D. M. Ney. Anabolic effects of insulin-like growth factor I in calorie restricted and ad libitum fed rats. Nutr. Res. 10: 1151-1160, 1990.
42. Zenobi, P. D., S. Graf, H. Ursprung, and E. R. Froesch. Effects of insulin-like growth factor-1 on glucose tolerance, insulin levels, and insulin secretion. J. Clin. Invest. 89: 1908-1913, 1992.