Neuropeptide Y enhances potassium excretion by mechanisms distinct from those controlling sodium excretion

Canadian Journal of Physiology and Pharmacology

Volumn 78, Issue 2, 2000, Pages 93-99

  Bischoff, Angela ^a   Michel, Martin C ^a,b  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

Angiotensin II; Cyclooxygenase; Neuropeptide Y; Potassium excretion; Sodium excretion

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; BRADYKININ; BRADYKININ B2 RECEPTOR ANTAGONIST; CALCIUM ION; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ICATIBANT; INDOMETACIN; LOSARTAN; NEUROPEPTIDE Y; NIFEDIPINE; POTASSIUM ION; PROSTAGLANDIN SYNTHASE INHIBITOR; RAMIPRILAT; RECEPTOR;

ARTICLE; CONTROLLED STUDY; DIURESIS; GLOMERULUS FILTRATION RATE; KALIURESIS; KIDNEY BLOOD FLOW; KIDNEY FUNCTION; MALE; NATRIURESIS; NONHUMAN; POTASSIUM EXCRETION; POTASSIUM URINE LEVEL; PRIORITY JOURNAL; RAT; SODIUM EXCRETION;

EID: 0034055983     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y99-121     Document Type: Article

References (15)

1. Bischoff, A., and Michel, M.C. 1998a. Renal effects of neuropeptide Y. Pfluegers Arch. Eur. J. Physiol. 435: 443-453.
2. 5 receptor subtype. Endocrinology 139: 3018-3021.
3. Bischoff, A., and Michel, M.C. 1999. Nifedipine attenuates neuropeptide Y effects in vivo. Br. J. Pharmacol. 126: 32P. (Abstr.)
4. Bischoff, A., Erdbrügger, W., Smits, J., and Michel, M.C. 1996. Neuropeptide Y-enhanced diuresis and natriuresis in anaesthetized rats is independent of renal blood flow reduction. J. Physiol. (London), 495: 525-534.
5. 5 are involved in the renal effects of neuropeptide Y. Br. J. Pharmacol. 120: 1335-1343.
6. Bischoff, A., Limmroth, V., and Michel, M.C. 1998a. Indomethacin inhibits the natriuretic effects of neuropeptide Y in anaesthetized rats. J. Pharmacol. Exp. Ther. 286: 704-708.
7. Bischoff, A., Rascher, W., and Michel, M.C. 1998b. Bradykinin may be involved in neuropeptide Y-induced diuresis, natriuresis, and calciuresis. Am. J. Physiol. 275: F502-F509.
8. Colmers, W.F., and Bleakman, D. 1994. Effects of neuropeptide Y on the electrical properties of neurons. Trends Neurosci. 17: 373-379.
9. 1 receptor antagonist: a review of its pharmacological properties. Regul. Pept. 65: 71-77.
10. Firth, J.D., Raine, A.E.G., and Ledingham, J.G.G. 1990. The mechanism of pressure natriuresis. J. Hypertens. 8: 97-103.
11. Hackenthal, E., Aktories, K., Jakobs, K.H., and Lang, R.E. 1987. Neuropeptide Y inhibits renin release by a pertussis toxin-sensitive mechanism. Am. J. Physiol. 252: F543-F550.
12. Halperin, M.L., and Kamel, S.K. 1998. Potassium. Lancet, 352: 135-140.
13. McDermott, B.J., Millar, B.C., and Piper, H.M. 1993. Cardiovascular effects of neuropeptide Y: receptor interactions and cellular mechanisms. Cardiovasc. Res. 27: 893-905.
14. +-ATPase activity. Kidney Int. 45: 1606-1613.
15. Smyth, D.D., Blandford, D.E., and Thom, S.L. 1988. Disparate effects of neuropeptide Y and clonidine on the excretion of sodium and water in the rat. Eur. J. Pharmacol. 152: 157-162.