Neuropeptide Y-enhanced diuresis and natriuresis in anaesthetized rats is independent of renal blood flow reduction

Journal of Physiology

Volumn 495, Issue 2, 1996, Pages 525-534

  Bischoff, Angela ^a   Erdbrügger, Wilhelm ^a   Smits, Jos ^b   Michel, Martin C ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CREATININE; NEUROPEPTIDE Y; POTASSIUM; SODIUM; VASOCONSTRICTOR AGENT;

ABDOMINAL AORTA; ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; CALCIUM EXCRETION; CONTROLLED STUDY; CREATININE CLEARANCE; DIURESIS; HEART RATE; KIDNEY BLOOD FLOW; KIDNEY BLOOD VESSEL; KIDNEY CAPSULE; KIDNEY COLLECTING TUBULE; KIDNEY DISTAL TUBULE; KIDNEY PERFUSION; MALE; MEAN ARTERIAL PRESSURE; NATRIURESIS; NONHUMAN; PERFUSION PRESSURE; POTASSIUM EXCRETION; PRIORITY JOURNAL; RAT; SODIUM EXCRETION; URINE;

EID: 0029742097     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.1996.sp021612     Document Type: Article

References (22)

1. ALLEN, J. M., RAINE, A. E. G., LEDINGHAM, J. G. G. & BLOOM, S. R. (1985). Neuropeptide Y - A novel renal peptide with vasoconstrictor and natriuretic activity. Clinical Science 68, 373-377.
2. BALLESTA, J., POLAK, J. M., ALLEN, J. M. & BLOOM, S. R. (1984). The nerves of the juxtaglomerula apparatus of man and other mammals contain the potent peptide NPY. Histochemistry 80, 483-485.
3. BISCHOFF, A., ERDBRÜGGER, W. & MICHEL, M. C. (1994). Indomethacine abolishes diuretic and natriuretic effects of NPY but not reductions in renal blood flow. FASEB Journal 8, A585.
4. BISCHOFF, A. & MICHEL, M. C. (1995). Do NPY-induced diuresis and natriuresis involve a neuronally-released factor? The Physiologist 38, A258.
5. DIETRICH, M. S., FRETSCHNER, M., NOBILING, R., PERSSON, P. B. & STEINHAUSEN, M. (1991). Renovascular effects of neuropeptide Y in the split hydronephrotic rat kidney: non-uniform pattern of vascular reactivity. Journal of Physiology 444, 303-315.
6. ECHTENKAMP, S. F. & DANDRIDGE, P. F. (1989). Renal actions of neuropeptide Y in the primate. American Journal of Physiology 256, F524-531.
7. 2+ and calmodulin. Journal of Pharmacology and Experimental Therapeutics 246, 479-484.
8. FIRTH, J. D., RAINE, A. E. G. & LEDINGHAM, J. G. G. (1990). Editorial review. The mechanism of pressure natriuresis. Journal of Hypertension 8, 97-103.
9. HACKENTHAL, E., AKTORIES, K., JAKOBS, K. H. & LANG, R. E. (1987). Neuropeptide Y inhibits renin release by a pertussis toxin-sensitive mechanism. American Journal of Physiology 252, F543-550.
10. KHRAIBI, A. A. & KNOX, F. G. (1989). Effect of renal decapsulation on renal interstitial hydrostatic pressure and natriuresis. American Journal of Physiology 257, R44-48.
11. KNIGHT, D. S., FABRE, R. D. & BEAL, J. A. (1989). Identification of noradrenergic nerve terminals immunoreactive for neuropeptide Y and vasoactive intestinal peptide in rat kidney. The American Journal of Anatomy 184, 190-204.
12. LE NOBLE, J. L. M. L., STRUYKER-BOUDIER, H. A. J. & SMITS, J. F. M. (1987). Differential effects of general anesthetics on regional vasoconstrictor responses in the rat. Archiv of International Pharmacodynamics 289, 82-92.
13. 2+ mobilization in HEL-cells. British Journal of Pharmacology 112, 499-504.
14. MINSON, R., MCRITCHIE, R. & CHALMERS, J. (1989). Effects of neuropeptide Y on the renal, mesenteric and hindlimb vascular beds of the conscious rabbit. Journal of the Autonomic Nervous System 27, 139-146.
15. OELLERICH, W. F. & MALIK, K. U. (1993). Neuropeptide Y modulates the vascular response to periarterial nerve stimulation primarily by a postjunctional action in the isolated perfused rat kidney. Journal of Pharmacology and Experimental Therapeutics 266, 1321-1329.
16. 2, NPY and angiotensin II receptors. Naunyn-Schmiedeberg's Archives of Pharmacology 340, 379-385.
17. PERNOW, J. & LUNDBERG, J. M. (1989b). Release and vasoconstrictor effects of neuropeptide Y in relation to non-adrenergic sympathetic control of RBF in the pig. Acta Physiologica Scandinavica 136, 507-517.
18. PERSSON, P. B., EHMKE, H., NAFZ, B., LANG, R., HACKENTHAL, E., NOBILING, R., DIETRICH, M. S. & KIRCHHEIM, H. R. (1991). Effects of neuropeptide Y on renal function and its interaction with sympathetic stimulation in conscious dogs. Journal of Physiology 444, 289-302.
19. RIEß, M., BOHMANN, C., SCHAIBLE, U., MICHEL, M. C. & RUMP, L. C. (1995). Pre- and postjunctional effects of neuropeptide Y in human and rabbit isolated tissues. Naunyn-Schmiedeberg's Archives of Pharmacology 351, suppl., R139.
20. ROMERO, J. C. & KNOX, F. G. (1988). Mechanisms underlying pressure-related natriuresis: the role of the renin-angiotensin and prostaglandin systems. Hypertension 11, 724-738.
21. SMITS, J. F. M., KASBERGEN, C. M., VAN ESSEN, H., KLEINJANS, J. C. & STRUYKER-BOUDIER, H. A. J. (1983). Chronic local infusion into the renal artery of unrestrained rats. American Journal of Physiology 244, H304-307.
22. SMYTH, D. D., BLANDFORD, D. E. & THOM, S. L. (1988). Disparate effects of neuropeptide Y and clonidine on the excretion of sodium and water in the rat. European Journal of Pharmacology 152, 157-162.