Spontaneous apoptotic DNA fragmentation in cultured guinea pig gastric mucosal cells

Digestive Diseases and Sciences

Volumn 45, Issue 2, 2000, Pages 291-297

  Tsutsumi, Shinji ^a,b,c   Rokutan, Kazuhito ^a,b,c   Tsuchiya, Tomofusa ^a,b,c   Mizushima, Tohru ^a,b,c  

^a OKAYAMA UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Apoptosis; Caspase; Gastric mucosal cells; Pit cell lineage

Indexed keywords

CASPASE; DNA FRAGMENT;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL CYCLE; CELL DEATH; GUINEA PIG; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; STOMACH MUCOSA;

ANIMALS; APOPTOSIS; CASPASES; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; DNA FRAGMENTATION; GASTRIC MUCOSA; GUINEA PIGS; MALE; PROTEIN BIOSYNTHESIS; TIME FACTORS;

EID: 0034053041     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1005404424698     Document Type: Article

References (18)

1. 1. Karam SM, Leblond CP: Dynamics of epithelial cells in the corpus of the mouse stomach. II. Outward migration of pit cells. Anat Rec 236:280-296, 1993
2. 2. Anti M, Armuzzi A, Gasbarrini A, Gasbarrini G: Importance of changes in epithelial cell turnover during Helicobacter pylori infection in gastric carcinogenesis. Gut 43:S27-S32, 1998
3. 3. Moss SF, Calam J, Agarwal B, Wang S, Holt PR: Induction of gastric epithelial apoptosis by Helicobacter pylori. Gut 38:498-501, 1996
4. 4. Rudi J, Kuck D, Strand S, Herbay AV, Mariani SM, Krammer PH, Galle PR, Stremmel W: Involvement of the CD95 (APO-I/Fas) receptor and ligand system in Helicobacter pylori-induced gastric epithelial apoptosis. J Clin Invest 102:1506-1514, 1998
5. 5. Wagner S, Beil W, Westermann J, Logan RP, Bock CT, Trautwein C, Bleck JS, Manns MP: Regulation of gastric epithelial cell growth by Helicobacter pylori: Evidence for a major role of apoptosis. Gastroenterology 113:1836-1847, 1997
6. 6. Milligan CE, Schwartz LM: Programmed cell death during animal development. Br Med Bull 53:570-590, 1997
7. 7. Que FG, Gores GJ: Cell death by apoptosis: Basic concepts and disease relevance for the gastroenterologist. Gastroenterology 110:1238-1243, 1996
8. 8. Potten CS, Wilson JW, Booth C: Regulation and significance of apoptosis in the stem cells of the gastrointestinal epithelium. Stem Cells 15:82-93, 1997
9. 9. Benedetti A, Mancini R, Marucci L, Paolucci F, Jezequel AM, Orlandi F: Quantitative study of apoptosis in normal rat gastroduodenal mucosa. J Gastroenterol Hepatol 5:369-374, 1990
10. 10. Hall PA, Coates PJ, Ansari B, Hopwood D: Regulation of cell number in the mammalian gastrointestinal tract: the importance of apoptosis. J Cell Sci 107:3569-3577, 1994
11. 11. Ogihara S, Yamada M, Saito T, Shono M, Rokutan K: Insulin potentiates mitogenic effect of epidermal growth factor on cultured guinea pig gastric mucous cells. Am J Physiol 271:G104-G112, 1996
12. 12. Rokutan K, Yamada M, Torigoe J, Saito T: Transforming growth factor-beta inhibits proliferation and maturation of cultured guinea pig gastric pit cells. Am J Physiol 275:G526-G533, 1998
13. 13. Teshima S, Rokutan K, Nikawa T, Kishi K: Guinea pig gastric mucosal cells produce abundant superoxide anion through an NADPH oxidase-like system. Gastroenterology 115:1186-1196, 1998
14. 14. Hirakawa T, Rokutan K, Nikawa T, Kishi K: Geranylgeranylacetone induces heat shock proteins in cultured guinea pig gastric mucosal cells and rat gastric mucosa. Gastroenterology 111:345-357, 1996
15. 15. Mizushima T, Tsutsumi S, Rokutan K, Tsuchiya T: Suppression of ethanol-induced apoptotic DNA fragmentation by geranylgeranylacetone in cultured guinea pig gastric mucosal cells. Dig Dis Sci (in press)
16. 16. Chandler JM, Cohen GM, MacFarlane M: Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver. J Biol Chem 273:10815-10818, 1998
17. 17. Gamen S, Anel A, Lasierra P, Alava MA, Martinez-Lorenzo MJ, Pineiro A, Naval J: Doxorubicin-induced apoptosis in human T-cell leukemia is mediated by caspase-3 activation in a Fas-independent way. FEBS Lett 417:360-364, 1997
18. 18. Ito M, Fujii A, Suzuki Y: Healing-promoting action of teprenone, a new antiulcer agent on acetic acid ulcer in rats. Jpn J Pharmacol 38:287-293, 1985