Efficient synthesis and biological evaluation of all A-ring diastereomers of 1α,25-dihydroxyvitamin D3 and its 20-epimer

Bioorganic and Medicinal Chemistry

Volumn 8, Issue 1, 2000, Pages 123-134

  Fujishima, Toshie ^a   Konno, Katsuhiro ^a   Nakagawa, Kimie ^b   Kurobe, Mayuko ^b   Okano, Toshio ^b   Takayama, Hiroaki ^a  

^a TEIKYO UNIVERSITY   (Japan)

^b KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Antiproliferative agents; Hormones; Receptors; Vitamins

Indexed keywords

CALCITRIOL DERIVATIVE; HYDROXYL GROUP; PALLADIUM; VITAMIN D BINDING PROTEIN; VITAMIN D RECEPTOR;

ARTICLE; BONE MINERAL; BONE MINERALIZATION; CATALYST; CELL DIFFERENTIATION; CELL STRAIN HL 60; DIASTEREOISOMER; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROXYLATION; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIGENS, SURFACE; CALCITRIOL; DRUG EVALUATION; MAGNETIC RESONANCE SPECTROSCOPY; MALE; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RECEPTORS, CALCITRIOL; STEREOISOMERISM;

OXY;

EID: 0034051008     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00262-X     Document Type: Article

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