Structure of a closed form of human malic enzyme and implications for catalytic mechanism

Nature Structural Biology

Volumn 7, Issue 3, 2000, Pages 251-257

  Yang, Zhiru ^a   Floyd, Daniel L ^a   Loeber, Gerhard ^b   Tong, Liang ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b BOEHRINGER INGELHEIM RCV GMBH AND CO KG   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

MAGNESIUM ION; MALATE DEHYDROGENASE (DECARBOXYLATING); MALONIC ACID DERIVATIVE; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXALIC ACID; TARTRONIC ACID;

ALLOSTERISM; ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME STRUCTURE; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

ALLOSTERIC REGULATION; BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROGEN BONDING; MAGNESIUM; MALATE DEHYDROGENASE; MALONATES; MANGANESE; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NAD; OXALIC ACID; OXYGEN; PROTEIN STRUCTURE, QUATERNARY; STRUCTURE-ACTIVITY RELATIONSHIP; TARTRONATES; WATER;

EID: 0034049525     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/73378     Document Type: Article

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