Building three-dimensional structures of HIV-1 coreceptor CCR5 and its interaction with antagonist TAK779 by comparative molecular modeling

Acta Pharmacologica Sinica

Volumn 21, Issue 6, 2000, Pages 521-528

  Huang, Xiao Qin ^a   Jiang, Hua Liang ^a   Luo, Xiao Min ^a   Chen, Kai Xian ^a   Ji, Ru Yun ^a   Cao, Yang ^b   Pei, Gang ^c  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b SOOCHOW UNIVERSITY   (China)

^c INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

CCR5 receptor; Computer aided design; HIV 1; Molecular structure; TAK 779

Indexed keywords

ANTIRETROVIRUS AGENT; CHEMOKINE RECEPTOR CCR5; N [4 [[[6,7 DIHYDRO 2 (4 METHYLPHENYL) 5H BENZOCYCLOHEPTEN 8 YL]CARBONYL]AMINO]BENZYL] N,N DIMETHYL 2H TETRAHYDROPYRAN 4 AMINIUM CHLORIDE; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; COMPUTER AIDED DESIGN; DRUG RECEPTOR BINDING; DRUG STRUCTURE; HYDROGEN BOND; MOLECULAR INTERACTION; MOLECULAR MODEL; PROTEIN STRUCTURE; QUANTUM MECHANICS;

AMIDES; BINDING SITES; COMPUTER-AIDED DESIGN; HIV INFECTIONS; HIV-1; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN CONFORMATION; QUATERNARY AMMONIUM COMPOUNDS; RECEPTORS, CCR5;

EID: 0034048041     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

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