메뉴 건너뛰기




Volumn 21, Issue 6, 2000, Pages 1213-1219

Characterization of an ATP-dependent pathway of activation for the heterocyclic amine carcinogen N-hydroxy-2-amino-3-methylimidazo[4,5-f]quinoline

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 3 METHYLIMIDAZO[4,5 F]QUINOLINE; ACETYL COENZYME A; ADENOSINE TRIPHOSPHATE; DAIDZEIN; GENISTEIN; STAUROSPORINE; TYRPHOSTIN;

EID: 0034047351     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/21.6.1213     Document Type: Article
Times cited : (11)

References (52)
  • 1
    • 0022007203 scopus 로고
    • Carcinogenicity of mutagenic heterocyclic amines formed during the cooking process
    • Sugimura, T. (1985) Carcinogenicity of mutagenic heterocyclic amines formed during the cooking process. Mutat. Res., 150, 33-41.
    • (1985) Mutat. Res. , vol.150 , pp. 33-41
    • Sugimura, T.1
  • 2
    • 0021881236 scopus 로고
    • Multipotential Carcinogenicity of the fried food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in rats
    • Tanaka, T., Barnes, W.S., Williams, G.S. and Weisburger, J.H. (1985) Multipotential Carcinogenicity of the fried food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in rats. Jpn. J. Cancer Res., 76, 570-576.
    • (1985) Jpn. J. Cancer Res. , vol.76 , pp. 570-576
    • Tanaka, T.1    Barnes, W.S.2    Williams, G.S.3    Weisburger, J.H.4
  • 3
    • 0021125918 scopus 로고
    • Demonstration of Carcinogenicity in F344 rats of 2-amino-3-methylimidazo[4.5-f]quinoline, from broiled sardine, fried beef and beef extract
    • Takayama, S., Nakatsuru, Y., Masuda, M., Ohgaki, H., Sato, S. and Sugimura, T. (1984) Demonstration of Carcinogenicity in F344 rats of 2-amino-3-methylimidazo[4.5-f]quinoline, from broiled sardine, fried beef and beef extract. Jpn. J. Cancer Res., 75, 467-470.
    • (1984) Jpn. J. Cancer Res. , vol.75 , pp. 467-470
    • Takayama, S.1    Nakatsuru, Y.2    Masuda, M.3    Ohgaki, H.4    Sato, S.5    Sugimura, T.6
  • 6
    • 0029875810 scopus 로고    scopus 로고
    • DNA adduct formation of the food-derived mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in nonhuman primates undergoing carcinogen bioassay
    • Turesky, R.J., Gremaud, E., Markovic, J. and Snyderwine, E.G. (1996) DNA adduct formation of the food-derived mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in nonhuman primates undergoing carcinogen bioassay. Chem. Res. Toxicol., 9, 403-408.
    • (1996) Chem. Res. Toxicol. , vol.9 , pp. 403-408
    • Turesky, R.J.1    Gremaud, E.2    Markovic, J.3    Snyderwine, E.G.4
  • 7
    • 0028376242 scopus 로고
    • Induction of hepatocellular carcinoma in nonhuman primates by the food mutagen 2-amino-3-methylimidazo[4.5-f]quinoline
    • Adamson, R.H., Takayama, S., Sugimura, T. and Thorgeirsson, U.P. (1994) Induction of hepatocellular carcinoma in nonhuman primates by the food mutagen 2-amino-3-methylimidazo[4.5-f]quinoline. Environ. Health Perspect., 102, 190-193.
    • (1994) Environ. Health Perspect. , vol.102 , pp. 190-193
    • Adamson, R.H.1    Takayama, S.2    Sugimura, T.3    Thorgeirsson, U.P.4
  • 8
    • 0028377027 scopus 로고
    • Cardiac damage induced by 2-amino-3-methylimidazo[4,5-f]quinoline in nonhuman primates
    • Thorgeirsson, U.P., Farb, A., Virmani, R. and Adamson, R.H. (1994) Cardiac damage induced by 2-amino-3-methylimidazo[4,5-f]quinoline in nonhuman primates. Environ. Health Perspect., 102, 194-199.
    • (1994) Environ. Health Perspect. , vol.102 , pp. 194-199
    • Thorgeirsson, U.P.1    Farb, A.2    Virmani, R.3    Adamson, R.H.4
  • 13
    • 0026447831 scopus 로고
    • Intra-and inter-individual variability in systemic exposure in man to MelQx and PhIP, carcinogens present in cooked beef
    • Lynch, A.M., Knize, M.G., Boobis, A.R., Gooderham, N.J., Davis, D.S. and Murray, S. (1992) Intra-and inter-individual variability in systemic exposure in man to MelQx and PhIP, carcinogens present in cooked beef. Cancer Res., 52, 6216-6223.
    • (1992) Cancer Res. , vol.52 , pp. 6216-6223
    • Lynch, A.M.1    Knize, M.G.2    Boobis, A.R.3    Gooderham, N.J.4    Davis, D.S.5    Murray, S.6
  • 15
    • 0025296345 scopus 로고
    • Metabolism of 2-acetylamino-fluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450
    • McManus, M.E., Burgess, W.M., Veronese, M.E., Huggett, A., Quattrochi, L.C. and Tukey, R.H. (1990) Metabolism of 2-acetylamino-fluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450. Cancer Res., 50, 3367-3376.
    • (1990) Cancer Res. , vol.50 , pp. 3367-3376
    • McManus, M.E.1    Burgess, W.M.2    Veronese, M.E.3    Huggett, A.4    Quattrochi, L.C.5    Tukey, R.H.6
  • 16
    • 0023853676 scopus 로고
    • Mutagenicity and in vitro covalent DNA binding of 2-hydroxyamino-3-methylimidazolo[4,5-f]quinoline
    • Snyderwine, E.G., Wirth, P.J., Roller, P.P., Adamson, R.H., Sato, S. and Thorgeirsson, S.S. (1988) Mutagenicity and in vitro covalent DNA binding of 2-hydroxyamino-3-methylimidazolo[4,5-f]quinoline. Carcinogenesis, 9, 411-418.
    • (1988) Carcinogenesis , vol.9 , pp. 411-418
    • Snyderwine, E.G.1    Wirth, P.J.2    Roller, P.P.3    Adamson, R.H.4    Sato, S.5    Thorgeirsson, S.S.6
  • 17
    • 0028904047 scopus 로고
    • Species differences in the biotransformation of the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4.5-b]pyridine by hepatic microsomes and cytosols from humans, rats and mice
    • Lin, D.-X., Lang, N.P. and Kadlubar, F.F. (1995) Species differences in the biotransformation of the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4.5-b]pyridine by hepatic microsomes and cytosols from humans, rats and mice. Drug Metab. Dispos., 23, 518-524.
    • (1995) Drug Metab. Dispos. , vol.23 , pp. 518-524
    • Lin, D.-X.1    Lang, N.P.2    Kadlubar, F.F.3
  • 18
    • 0342308092 scopus 로고
    • Reaction of N-hydroxylamine and N-acetoxy derivatives of 2-amino-3-methylimidazo[4,5-f]quinoline with DNA. Synthesis and identification of N-(deoxyguanosin-8-yl)-IQ
    • Snyderwine, E.G., Roller, P.P., Adamson, R.H., Sato, S. and Thorgeirsson, S.S. (1988) Reaction of N-hydroxylamine and N-acetoxy derivatives of 2-amino-3-methylimidazo[4,5-f]quinoline with DNA. Synthesis and identification of N-(deoxyguanosin-8-yl)-IQ. Carcinogenesis, 10, 335-341.
    • (1988) Carcinogenesis , vol.10 , pp. 335-341
    • Snyderwine, E.G.1    Roller, P.P.2    Adamson, R.H.3    Sato, S.4    Thorgeirsson, S.S.5
  • 19
    • 0343613122 scopus 로고
    • Photolysis of arylazides and generation of highly electrophilic DNA-binding and mutagenic intermediates
    • Wild, D., Dirr, A., Fasshauer, I. and Henschler, D. (1989) Photolysis of arylazides and generation of highly electrophilic DNA-binding and mutagenic intermediates. Carcinogenesis, 12, 1091-1096.
    • (1989) Carcinogenesis , vol.12 , pp. 1091-1096
    • Wild, D.1    Dirr, A.2    Fasshauer, I.3    Henschler, D.4
  • 20
    • 0026521971 scopus 로고
    • Quantitative structure-activity relationships of mutagenic aromatic and heteroaromatic azides and amines
    • Sabbioni, G. and Wild, D. (1992) Quantitative structure-activity relationships of mutagenic aromatic and heteroaromatic azides and amines. Carcinogenesis, 13, 709-713.
    • (1992) Carcinogenesis , vol.13 , pp. 709-713
    • Sabbioni, G.1    Wild, D.2
  • 21
    • 0023749970 scopus 로고
    • DNA adduct formation of the carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline in target tissues of the F-344 rat
    • Schut, H.A.J., Putman, K.L. and Randerath, K. (1988) DNA adduct formation of the carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline in target tissues of the F-344 rat. Cancer Lett., 41, 345-352.
    • (1988) Cancer Lett. , vol.41 , pp. 345-352
    • Schut, H.A.J.1    Putman, K.L.2    Randerath, K.3
  • 22
    • 0029166942 scopus 로고
    • DNA adduct formation of the food carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline in liver, kidney and colo-rectum of rats
    • Turesky, R.J. and Markovic, J. (1995) DNA adduct formation of the food carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline in liver, kidney and colo-rectum of rats. Carcinogenesis, 16, 2275-2279.
    • (1995) Carcinogenesis , vol.16 , pp. 2275-2279
    • Turesky, R.J.1    Markovic, J.2
  • 23
    • 0027369714 scopus 로고
    • Enzymatic phase II activation of the N-hydroxylamines of IQ, MeIQx and PhIP by various organs of monkeys and rats
    • Davis, C.D., Schut, H.A.J. and Snyderwine, E.G. (1993) Enzymatic phase II activation of the N-hydroxylamines of IQ, MeIQx and PhIP by various organs of monkeys and rats. Carcinogenesis, 10, 2091-2096.
    • (1993) Carcinogenesis , vol.10 , pp. 2091-2096
    • Davis, C.D.1    Schut, H.A.J.2    Snyderwine, E.G.3
  • 25
    • 0003009327 scopus 로고
    • Experiments illustrating drug metabolism in vitro
    • La Du, B.N., Mandel, H.G. and Way, E.L. (eds). Williams and Wilkins, Baltimore, MD
    • Mazel, P. (1971) Experiments illustrating drug metabolism in vitro. In La Du, B.N., Mandel, H.G. and Way, E.L. (eds) Fundementals of Drug Metabolism ami Drug Disposition. Williams and Wilkins, Baltimore, MD, pp. 546-582.
    • (1971) Fundementals of Drug Metabolism ami Drug Disposition , pp. 546-582
    • Mazel, P.1
  • 26
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 27
    • 0028095423 scopus 로고
    • Effects of human and rat glutathione S-transferases on the covalent DNA binding of the N-acetoxy derivatives of heterocyclic amine carcinogens in vitro: A possible mechanism of organ-specificity in their carcinogenesis
    • Lin, D.-X., Meyer, D.J., Ketterer, B., Lang, N.P. and Kadlubar, F.F. (1994) Effects of human and rat glutathione S-transferases on the covalent DNA binding of the N-acetoxy derivatives of heterocyclic amine carcinogens in vitro: a possible mechanism of organ-specificity in their carcinogenesis. Cancer Res., 54, 4920-4926.
    • (1994) Cancer Res. , vol.54 , pp. 4920-4926
    • Lin, D.-X.1    Meyer, D.J.2    Ketterer, B.3    Lang, N.P.4    Kadlubar, F.F.5
  • 28
    • 0018850985 scopus 로고
    • A simple, rapid and sensitive DNA assay procedure
    • Labarca, C. and Paigen, K. (1980) A simple, rapid and sensitive DNA assay procedure. Anal. Biochem., 102, 344-352.
    • (1980) Anal. Biochem. , vol.102 , pp. 344-352
    • Labarca, C.1    Paigen, K.2
  • 29
    • 0020038862 scopus 로고
    • Formation and identification of glutathione conjugates from 2-nitrosofluorene and N-hydroxy-2-aminofluorene
    • Mulder, G.J., Unruh, L.E., Evans, F.E., Ketterer, B. and Kadlubar, F.F. (1982) Formation and identification of glutathione conjugates from 2-nitrosofluorene and N-hydroxy-2-aminofluorene. Chem. Biol. Interact., 39, 111-127.
    • (1982) Chem. Biol. Interact. , vol.39 , pp. 111-127
    • Mulder, G.J.1    Unruh, L.E.2    Evans, F.E.3    Ketterer, B.4    Kadlubar, F.F.5
  • 30
    • 0023638696 scopus 로고
    • In vivo and in vitro formation of glutathione conjugates from the K-region epoxides of 1-nitropyrene
    • Djuric, Z., Coles, B., Fifer, E.K., Ketterer, B. and Beland, F.A. (1987) In vivo and in vitro formation of glutathione conjugates from the K-region epoxides of 1-nitropyrene. Carcinogenesis, 8, 1781-1786.
    • (1987) Carcinogenesis , vol.8 , pp. 1781-1786
    • Djuric, Z.1    Coles, B.2    Fifer, E.K.3    Ketterer, B.4    Beland, F.A.5
  • 31
    • 0021133649 scopus 로고
    • Glutathione conjugate formation in the detoxification of ultimate and proximate carcinogens of N-methyl-4-aminoazobenzene
    • Coles, B., Ketterer, B. Beland, F.A. and Kadlubar, F.F. (1984) Glutathione conjugate formation in the detoxification of ultimate and proximate carcinogens of N-methyl-4-aminoazobenzene. Carcinogenesis, 5, 917-920.
    • (1984) Carcinogenesis , vol.5 , pp. 917-920
    • Coles, B.1    Ketterer, B.2    Beland, F.A.3    Kadlubar, F.F.4
  • 33
    • 0019882124 scopus 로고
    • Mitochondrial and cytosolic ATP/ADP ratios in rat liver in vivo
    • Schwenke, W.D., Soboll, S., Seitz, H.J. and Sies, H. (1981) Mitochondrial and cytosolic ATP/ADP ratios in rat liver in vivo. Biochem. J., 200, 405-408.
    • (1981) Biochem. J. , vol.200 , pp. 405-408
    • Schwenke, W.D.1    Soboll, S.2    Seitz, H.J.3    Sies, H.4
  • 34
    • 0023860481 scopus 로고
    • Induction of sulfamethazine acetylation by hydrocortisone in the rabbit
    • Reeves, P.T., Minchin, R.F. and Ilett, K.F. (1988) Induction of sulfamethazine acetylation by hydrocortisone in the rabbit. Drug Metab. Dispos., 16, 110-115.
    • (1988) Drug Metab. Dispos. , vol.16 , pp. 110-115
    • Reeves, P.T.1    Minchin, R.F.2    Ilett, K.F.3
  • 35
    • 0031136606 scopus 로고    scopus 로고
    • The importance of 3′-phosphoadenosine 5′-phosphosulfate (PAPS) in the regulation of sulfation
    • Klaassen, C.D. and Boles, J.W. (1997) The importance of 3′-phosphoadenosine 5′-phosphosulfate (PAPS) in the regulation of sulfation. FASEB J., 11, 404-418.
    • (1997) FASEB J. , vol.11 , pp. 404-418
    • Klaassen, C.D.1    Boles, J.W.2
  • 36
    • 0019829568 scopus 로고
    • The causes of cancer: Quantitative estimates of avoidable risks of cancer in the United States today
    • Doll, R. and Peto, R. (1981) The causes of cancer: quantitative estimates of avoidable risks of cancer in the United States today. J. Natl Cancer Inst., 66, 1191-1308.
    • (1981) J. Natl Cancer Inst. , vol.66 , pp. 1191-1308
    • Doll, R.1    Peto, R.2
  • 37
    • 0022778481 scopus 로고
    • Sulfamate formation is a major route for detoxification of 2-amino-3-methylimidazo[4,5-f]quinoline in the rat
    • Turesky, R.J., Skipper, P.L., Tannenbaum, S.R., Coles, B. and Ketterer, B. (1986) Sulfamate formation is a major route for detoxification of 2-amino-3-methylimidazo[4,5-f]quinoline in the rat. Carcinogenesis, 7, 1483-1485.
    • (1986) Carcinogenesis , vol.7 , pp. 1483-1485
    • Turesky, R.J.1    Skipper, P.L.2    Tannenbaum, S.R.3    Coles, B.4    Ketterer, B.5
  • 38
    • 0024320001 scopus 로고
    • Identification of sulfate and glucuronic acid conjugates of the 5-hydroxy derivative as major metabolites of 2-amino-3-methylimidazo[4,5-f]quinoline in rats
    • Luks, H.J., Spratt, J.E., Vavrek, M.T., Roland, S.F. and Weisburger, J.H. (1989) Identification of sulfate and glucuronic acid conjugates of the 5-hydroxy derivative as major metabolites of 2-amino-3-methylimidazo[4,5-f]quinoline in rats. Cancer Res., 49, 4407-4411.
    • (1989) Cancer Res. , vol.49 , pp. 4407-4411
    • Luks, H.J.1    Spratt, J.E.2    Vavrek, M.T.3    Roland, S.F.4    Weisburger, J.H.5
  • 40
    • 0032062180 scopus 로고    scopus 로고
    • Antimutagenicity of flavones and flavonols to heterocyclic amines by specific and strong inhibition of the cytochrome P450 1A family
    • Kanazawa, K., Yamashita, T., Ashida, H. and Danno, G. (1998) Antimutagenicity of flavones and flavonols to heterocyclic amines by specific and strong inhibition of the cytochrome P450 1A family. Biosci. Biotechnol. Biochem., 62, 970-977.
    • (1998) Biosci. Biotechnol. Biochem. , vol.62 , pp. 970-977
    • Kanazawa, K.1    Yamashita, T.2    Ashida, H.3    Danno, G.4
  • 41
    • 0030866720 scopus 로고    scopus 로고
    • The inhibition by flavonoids of 2-amino-3-methylimidazo[4,5-f]quinoline metabolic activation to a mutagen: A structure-activity relationship study
    • Edenharder, R., Rauscher, R. and Platt, K.L. (1997) The inhibition by flavonoids of 2-amino-3-methylimidazo[4,5-f]quinoline metabolic activation to a mutagen: a structure-activity relationship study. Mutat. Res., 379, 21-32.
    • (1997) Mutat. Res. , vol.379 , pp. 21-32
    • Edenharder, R.1    Rauscher, R.2    Platt, K.L.3
  • 42
    • 0031425480 scopus 로고    scopus 로고
    • Effects of tea and chlorophyllin on the mutagenicity of N-hydroxy-IQ: Studies of enzyme inhibition, molecular complex formation and degradation/scavenging of the active metabolites
    • Hernaez, J., Xu, M. and Dashwood, R. (1997) Effects of tea and chlorophyllin on the mutagenicity of N-hydroxy-IQ: studies of enzyme inhibition, molecular complex formation and degradation/scavenging of the active metabolites. Environ. Mol. Mutagen., 30, 468-474.
    • (1997) Environ. Mol. Mutagen. , vol.30 , pp. 468-474
    • Hernaez, J.1    Xu, M.2    Dashwood, R.3
  • 43
    • 0031706092 scopus 로고    scopus 로고
    • Inhibition of PhIP mutagenicity by caffeine, lycopene, daidzein and genistein
    • Weisburger, J.H., Dolan, L. and Pitman, B. (1998) Inhibition of PhIP mutagenicity by caffeine, lycopene, daidzein and genistein. Mutat. Res., 416, 125-128.
    • (1998) Mutat. Res. , vol.416 , pp. 125-128
    • Weisburger, J.H.1    Dolan, L.2    Pitman, B.3
  • 44
    • 0027154091 scopus 로고
    • Antimutagenic effects of flavonoids, chalcones and structurally related compounds on the activity of 2-amino-3-methylimidazo[4.5-f]quinoline (IQ) and other heterocyclic amine mutagens from cooked food
    • Edenharder, R., von Petersdorff, I. and Rauscher, R. (1993) Antimutagenic effects of flavonoids, chalcones and structurally related compounds on the activity of 2-amino-3-methylimidazo[4.5-f]quinoline (IQ) and other heterocyclic amine mutagens from cooked food. Mutat. Res., 287, 261-274.
    • (1993) Mutat. Res. , vol.287 , pp. 261-274
    • Edenharder, R.1    Von Petersdorff, I.2    Rauscher, R.3
  • 45
    • 0030811507 scopus 로고    scopus 로고
    • Dietary phytoestrogens
    • Kurzer, M.S. and Xu, X. (1997) Dietary phytoestrogens. Annu. Rev. Nutr., 17, 353-381.
    • (1997) Annu. Rev. Nutr. , vol.17 , pp. 353-381
    • Kurzer, M.S.1    Xu, X.2
  • 46
    • 0028216956 scopus 로고
    • Soy intake and cancer risk: A review of the in vitro and in vivo data
    • Messina, M.J., Persky, V., Setchell, K.D.R. and Barnes, S. (1994) Soy intake and cancer risk: a review of the in vitro and in vivo data. Nutr. Cancer, 21, 113-131.
    • (1994) Nutr. Cancer , vol.21 , pp. 113-131
    • Messina, M.J.1    Persky, V.2    Setchell, K.D.R.3    Barnes, S.4
  • 47
    • 0032523809 scopus 로고    scopus 로고
    • Receptor-mediated endocytosis of albumin by kidney proximal tubule cells is regulated by phosphatidylinositide 3-kinase
    • Brunskill, N.J., Stuart, J., Tobin, A.B., Walls, J. and Nahorski, S. (1998) Receptor-mediated endocytosis of albumin by kidney proximal tubule cells is regulated by phosphatidylinositide 3-kinase. J. Clin. Invest., 101, 2140-2150
    • (1998) J. Clin. Invest. , vol.101 , pp. 2140-2150
    • Brunskill, N.J.1    Stuart, J.2    Tobin, A.B.3    Walls, J.4    Nahorski, S.5
  • 48
    • 0030603158 scopus 로고    scopus 로고
    • Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isozymes
    • Gschwendt, M., Dieterich, S., Rennecke, J., Kittstein, W., Mueller, H.J. and Johannes, F.J. (1996) Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isozymes. FEBS Lett., 392, 77-80.
    • (1996) FEBS Lett. , vol.392 , pp. 77-80
    • Gschwendt, M.1    Dieterich, S.2    Rennecke, J.3    Kittstein, W.4    Mueller, H.J.5    Johannes, F.J.6
  • 49
    • 0031253655 scopus 로고    scopus 로고
    • Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2
    • Lawrie, A.M., Noble, M.E., Tunnah, P., Brown, N.R., Johnson, L.N. and Endicott, J.A. (1997) Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2. Nature Stuct. Biol., 4, 796-801.
    • (1997) Nature Stuct. Biol. , vol.4 , pp. 796-801
    • Lawrie, A.M.1    Noble, M.E.2    Tunnah, P.3    Brown, N.R.4    Johnson, L.N.5    Endicott, J.A.6
  • 50
    • 0030709470 scopus 로고    scopus 로고
    • Anti-thyroid isoflavones from soybean: Isolation, characterization and mechanisms of action
    • Divi, R.L., Chang, H.C. and Doerge, D.R. (1997) Anti-thyroid isoflavones from soybean: isolation, characterization and mechanisms of action. Biochem. Pharmacol., 54, 1087-1096.
    • (1997) Biochem. Pharmacol. , vol.54 , pp. 1087-1096
    • Divi, R.L.1    Chang, H.C.2    Doerge, D.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.