Incorporation of S-9 activation into an ER-α transactivation assay

Reproductive Toxicology

Volumn 14, Issue 3, 2000, Pages 207-216

  Charles, Grantley D ^a   Bartels, Michael J ^a   Gennings, C ^b   Zacharewski, Timothy R ^c   Freshour, Nancy L ^a   Bhaskar Gollapudi, B ^a   Carney, Edward W ^a  

^a DOW CHEMICAL COMPANY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Endocrine toxicity; Estrogenicity; HPTE; MCF 7 cells; Metabolism; Methoxychlor; Reporter gene; S 9 activation

Indexed keywords

AROCLOR 1254; BETA GALACTOSIDASE; ESTRADIOL; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; LUCIFERASE; METHOXYCHLOR;

ANIMAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOASSAY; CELL CULTURE; CELL METABOLISM; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ESTROGEN ACTIVITY; GENETIC TRANSFECTION; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIVER CELL CULTURE; LIVER HOMOGENATE; LIVER MICROSOME; MALE; METABOLISM; METHODOLOGY; NONHUMAN; RAT; RAT STRAIN; REPORTER GENE; TRANSACTIVATION;

ANIMALS; AROCLOR 1254; BETA-GALACTOSIDASE; BIOLOGICAL ASSAY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; GENES, REPORTER; HUMANS; LUCIFERASES; MALE; METHOXYCHLOR; MICROSOMES, LIVER; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ESTROGEN; TRANS-ACTIVATION (GENETICS); TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA; MINK CELL FOCUS-FORMING VIRUS;

EID: 0034045772     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0890-6238(00)00070-8     Document Type: Article

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