Various stages of Schistosoma express Lewis(x), LacdiNAc, GalNAcβ1-4 (Fucα1-3)GlcNAc and GalNAcβ1-4(Fucα1-2Fucα1-3)GlcNAc carbohydrate epitopes: Detection with monoclonal antibodies that are characterized by enzymatically synthesized neoglycoproteins

Glycobiology

Volumn 10, Issue 6, 2000, Pages 601-609

  Van Remoortere, Alexandra ^a,b   Hokke, Cornelis H ^a,b   Van Dam, Govert J ^b   Van Die, Irma ^a   Deelder, André M ^b   Van Den Eijnden, Dirk H ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Antigenicity; Enzymatic synthesis; Fucose; Oligosaccharide; Schistosomiasis

Indexed keywords

EPITOPE; GLYCOPROTEIN; MONOCLONAL ANTIBODY;

ARTICLE; FUCOSYLATION; IMMUNE RESPONSE; IMMUNOFLUORESCENCE TEST; LIFE CYCLE; NONHUMAN; PARASITE DEVELOPMENT; PRIORITY JOURNAL; SCHISTOSOMA;

BOVINAE; SCHISTOSOMA; SCHISTOSOMA MANSONI; TREMATODA;

EID: 0034045731     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/10.6.601     Document Type: Article

References (39)

1. Andersson, M., Scarson, S. and Oberg, L. (1993) Synthesis of oligosaccharides with oligoethylene glycol spacers and their conversion into glycoconjugates using N,N,N′,N′′-tetramethyl (succinimido)uronium tetrafluoroborate as coupling reagent. Glycoconj. J., 10, 197-201.
2. Aronstein, W.S., Dalton, J.P., Weiss, J.B. and Strand, M. (1983) Identification of species-specific and gender-specific proteins and glycoproteins of three human schistosomes. J. Parasitol., 69, 1006-1017.
3. Bergwerff, A.A., Van Kuik, J.A., Schiphorst, W.E.C.M., Koeleman, C.A.M., Van den Eijnden, D.H., Kamerling, J.P. and Vliegenthart, J.F.G. (1993) Conversion of GalNAcβ1-4GlcNAcβ-OMe into GalNAcβ1-4 (Fucα1-3)GlcNAcβ-OMe using human milk α3/4-fucosyltransferase. Synthesis of a novel terminal element in glycoprotein glycans. FEBS Lett., 334, 133-138.
4. Bogers, J.J.P.M., Nibbeling, H.A., Van Marck, E.A. and Deelder, A.M. (1994) Immunofluorescent visualization of the excretory and gut system of Schistosoma mansoni confocal laser scanning microscopy. Am. J. Trop. Med. Hyg., 50, 612-619.
5. Bogers, J.J.P.M., Nibbeling, H.A., Singh, S.K., Deelder, A.M. and Van Marck, E.A. (1995) Ultrastructural immunolocalization of two circulating egg antigens in miracidia of Schistosoma mansoni. Parasitology. 110, 365-370.
6. Cummings, R.D. and Nyame, A.K. (1996) Glycobiology of schistosomiasis. FASEB J., 10, 838-848.
7. Cummings, R.D. and Nyame, A.K. (1999) Schistosome glycoconjugates. Biochim. Biophys. Acta. 1455, 363-374.
8. Dalton, J.P. and Strand M. (1987) Schistosoma mansoni polypeptides immunogenic in mice vaccinated with radiation-attenuated cercariae. J. Immunol., 139, 2474-2481.
9. Deelder, A.M., De Jonge, N., Boerman, O.C., Fillié, Y.E., Hilberath, G.W., Rotmans, J.P., Gerritse, M.J. and Schut, D.W.O.A. (1989) Sensitive determination of circulating anodic antigen in Schistosoma mansoni infected individuals by an enzyme-linked immunosorbent assay using monoclonal antibodies. Am. J. Trop. Med. Hyg., 40, 939-943.
10. Deelder, A.M., Van Dam, G.J., Kornelis, D., Fillié, Y.E. and Van Zeyl, R.J.M. (1996) Schistosoma - analysis of monoclonal antibodies reactive with the circulating antigens CCA and CAA. Parasitology, 112, 21-35.
11. DeVries, T., Norberg, T., Lonn, H. and Van den Eijnden, D.H. (1993) The use of human milk fucosyltransferase in the synthesis of tumor-associated trimeric X determinants. Eur. J. Biochem., 216, 769-777.
12. Habeeb, A.F. (1987) Schistosoma mansoni: chemical stabilization of cercariae by aldehydes. Exp. Parasitol., 64, 111-119.
13. Hokke, C.H., Neeleman, A.P., Koeleman, C.A.M. and Van den Eijnden, D.H. (1998) Identification of an α3-fucosyltransferase and a novel α2-fucosyltransferase activity in cercariae of the schistosome Trichobilharzia ocellata: biosynthesis of the Fucα→2Fucα1→3[Gal (NAc)β1→4]GlcNAc sequence. Glycobiology, 8, 393-406.
14. Joziasse, D.H., Schiphorst, W.E.C.M., Koeleman, C.A.M. and Van den Eijnden, D.H. (1993) Enzymatic synthesis of the α3-galactosyl-Le (x) tetrasaccharide - A potential ligand for selectin-type adhesion molecules. Biochem. Biophys. Res. Commun., 194, 358-367.
15. Kamath, V.P. and Hindsgaul, O. (1996) Synthesis of α- and β-L-Fuc p-(1→2)-α-L-Fuc p-(1→3)-β-D-Gal pNAc glycosides identified as termini of Schistosoma mansoni oligosaccharides. Carbohydr. Res., 280, 323-330.
16. Khoo, K.-H., Sarda, S., Xu, X., Caulfield, J.P., McNeil, M.R., Homans, S.W., Morris, H.R. and Dell, A. (1995) A unique multifucosylated -3GalNAcβ1-4GlcNAcβ1-3Galα1-motif constitutes the repeating unit of the complex O-glycans derived from the cercarial glycocalyx of Schistosoma mansoni. J. Biol. Chem., 270, 17114-17123.
17. Khoo, K.-H., Chatterjee, D., Caulfield, J.P., Morris, H.R. and Dell, A. (1997) Structural characterization of glycosphingolipids from the eggs of Schistosoma mansoni and Schistosoma japonicum. Glycobiology, 1, 653-661.
18. Ko, A.I., Dräger, U.C. and Harn, D.A. (1990) A Schistosoma mansoni epitope recognized by a protective monoclonal antibody is identical to the stage-specific embryonic antigen 1. Proc. Natl. Acad. Sci. USA, 87, 4159-4163.
19. Koster, B. and Strand, M. (1994) Schistosoma mansoni: immunolocalization of two different fucose-containing carbohydrate epitopes. Parasitology, 108, 433-446.
20. Levery, S.B., Weiss, J.B., Salyan, M.E.K., Roberts, C.E., Hakomori, S., Magnani, J.L. and Strand, M. (1992) Characterization of a series of novel fucose-containing glycosphingolipid immunogens from eggs of Schistosoma mansoni. J. Biol. Chem., 267, 5542-5551.
21. Linder, E. (1990) Cercarial kissing marks - no superficial make-up. Parasitol. Today, 12, 393-395.
22. Mulder, H., Spronk, B.A., Schachter, H., Neeleman, A.P., Van den Eijnden, D.H., De Jong-Brink, M., Kamerling, J.P. and Vliegenthart, J.F.G. (1995) Identification of a novel UDP-GalNAc:GlcNAcβ-R β1-4 N-acetylgalactosaminyltransferase from the albumen gland and connective tissue of the snail Lymnaea stagnalis. Eur. J. Biochem., 227, 175-185.
23. Nash, T.E., Nasir, U.D. and Jeanloz, R.W. (1977) Further purification and characterization of a circulating antigen in schistosomiasis. J. Immunol., 119, 1627-1633.
24. Nash, T.E. (1978) Antibody response to a polysaccharide antigen present in the schistosome gut. I. Sensitivity and specificity. Am. J. Trop. Med. Hyg., 27, 939-943.
25. Nash, T.E., Lunde, M.N. and Cheever, A.W. (1981) Analysis and antigenic activity of a carbohydrate fraction derived from adult Schistosoma mansoni. J. Immunol., 126, 805-810.
26. Nibbeling, H.M., Kahama, A.I., Van Zeyl, R.M. and Deelder, A.M. (1998) Use of monoclonal antibodies prepared against Schistosoma mansoni hatching fluid antigens for demonstration of Schistosoma haematobium circulating egg antigens in urine. Am. J. Trop. Med. Hyg., 58, 543-550.
27. Nourel Din, M.A., Kornelis, D., Van Zeyl, R.J. and Deelder, A.M. (1994) Immunologic characterization of two monoclonal antibodies reactive with repetitive carbohydrate epitopes of circulating Schistosoma mansoni egg antigen. Am. J. Trop. Med. Hyg., 50, 487-498.
28. Nyame, A.K., Smith, D.F., Damian, R.T. and Cummings, R.D. (1989) Complex-type asparagine-linked oligosaccharides in glycoproteins synthesized by Schistosoma mansoni adult males contain terminal β-linked N-acetylgalactosamine. J. Biol. Chem., 264, 3235-3243.
29. x determinants on myeloid cells. Exp. Parasitol., 82, 191-200.
30. Nyame, A.K., Leppänen, A.M., Debose-Boyd, R. and Cummings, R.D. (1999) Mice infected with Schistosoma mansoni generate antibodies to LacdiNAc (GalNAcβ1-4GlcNAc) determinants. Glycobiology, 9, 1029-1035.
31. Omer Ali, P., Smithers, S.R., Bickle, Q., Philips, S.M., Harn, D. and Simpson, A.J.G. (1988) Analysis of the anti-Schistosoma mansoni surface antibody response during murine infection and its potential contribution to protective immunity. J. Immunol., 140, 258-264.
32. Palcic, M.M., Heerze, L.D., Pierce, M. and Hindsgaul, O. (1988) The use of hydrophobia synthetic glycosides as acceptors in glycosyltransferase assays. Glycoconj. J., 5, 49-63.
33. Srivatsan, J., Smith, D.F. and Cummings, R.D. (1992) The human blood fluke Schistosoma mansoni synthesizes glycoproteins containing the Lewis x antigen. J. Biol. Chem., 267, 20196-20203.
34. Van Dam, G.J. and Deelder, A.M. (1996) Glycoproteins of parasites. In Montreuil, J., Vliegenthart, J.F.G. and Schachter, H. (eds.). Glycoproteins and Disease. Elsevier, Amsterdam, pp. 159-182.
35. Van Dam, G.J., Kornelis, D., Van Zeyl, R.J., Rotmans, J.P. and Deelder, A.M. (1993) Schistosoma mansoni: analysis of monoclonal antibodies reactive with gut-associated antigens. Parasitol Res., 79, 55-62.
36. Van Dam, G.J., Bergwerf, A.A., Thomas-Oates, J.E., Rotmans, J.P., Kamerling, J.P., Vliegenthart, J.F.G. and Deelder, A.M. (1994) The immunological reactive O-linked polysaccharide chains derived from circulating cathodic antigen isolated from the human blood fluke Schistosoma mansoni have Lewis x as repeating unit. Eur. J. Biochem., 225, 467-482.
37. Van Dam, G.J., Claas, F.H.J., Yazdanbakhsh, M., Kruize, Y.C.M, Van Keulen, A.C.I., Ferreira, S.T.M.F., Rotmans, J.P. and Deelder, A.M. (1996) Schistosoma mansoni excretory circulating cathodic antigen shares Lewis-x epitopes with a human granulocyte surface antigen and evokes host antibodies mediating complement-dependent lysis of granulocytes. Blood, 88, 4246-4251.
38. Weiss, J.B. and Strand, M. (1985) Characterization of developmentally regulated epitopes of egg glycoprotein antigens. J. Immunol., 135, 1421-1429.
39. Weiss, J.B., Magnani, J.L. and Strand, M. (1986) Identification of Schistosoma mansoni glycolipids that share immunogenic carbohydrate epitopes with glycoproteins. J. Immunol., 136, 4275-4282.