Osteoblast-like cells of the hypophysectomized rat: A model of aberrant osteoblast development

American Journal of Physiology - Endocrinology and Metabolism

Volumn 278, Issue 5 41-5, 2000, Pages

  Evans, Jodi F ^a   Yeh, James K ^a,b   Aloia, John F ^a,b  

^a WINTHROP UNIVERSITY HOSPITAL   (United States)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

Alkaline phosphatase; Differentiation; Mineralization potential; Proliferation

Indexed keywords

CALCIUM ION; COLLAGEN TYPE 1;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DENSITOMETRY; FEMALE; HYPOPHYSECTOMY; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

EID: 0034045149     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.2000.278.5.e832     Document Type: Article

References (30)

1. Aubin JE, Liu F, Malaval L, and Gupta AK. Osteoblast and chondroblast differentiation. Bone Suppl 17: 77S-83S, 1995.
2. Aubin JE, Turksen K, and Heersche JNM. Osteoblastic cell lineage. In: Cellular and Molecular Biology of Bone, edited by M. Noda. San Diego, CA: Academic, 1993, p. 1-45.
3. Barnard R, Martin TJ, and Waters MJ. Growth hormone (GH) receptors in clonal osteoblast-like cells mediate a mitogenic response to GH. Endocrinology 128: 1459-1464, 1991.
4. Birnbaum RS and Wiren KM. Changes in insulin-like growth factor-binding protein expression and secretion during the proliferation, differentiation, and mineralization of primary cultures of rat osteoblasts. Endocrinology 135: 223-230, 1994.
5. Chen M-M, Yeh JK, and Aloia JF. Skeletal alterations in hypophysectomized rats. II. A histomorphometric study on tibial cortical bone. Anat Rec 241: 513-518, 1995.
6. Chen M-M, Yeh JK, and Aloia JF. Histologic evidence: growth hormone completely prevents reduction in cortical bone gain and partially prevents cancellous osteopenia in the tibia of hypophysectomized rats. Anat Rec 249: 163-172, 1997.
7. Chevalley T, Strong DD, Mohan S, Baylink D, and Linkhart TA. Evidence for a role for insulin-like growth factor binding proteins in glucocorticoid inhibition of normal human osteoblast-like cell proliferation. Eur J Endocrinol 134: 591-601, 1996.
8. Currie GA. Platelet-derived growth factor requirements for in vitro proliferation of normal and malignant cells. Br J Cancer 43: 335-343, 1981.
9. Ernst E and Froesch ER. Growth-hormone dependent stimulation of osteoblast-like cells in serum-free cultures via local synthesis of insulin-like growth factor I. Biochem Biophys Res Commun 151: 142-147, 1988.
10. Eshet R, Werner H, Klinger B, Silbergeld A, Laron Z, LeRoith D, and Roberts CT. Up-regulation of insulin-like growth-factor-I (IGF-I) receptor gene expression in patients with reduced serum IGF-I levels. J Mol Endocrinol 10: 115-120, 1993.
11. Halstead LR, Scott MJ, Rifas L, and Avioli LV. Characterization of osteoblast-like cells from normal adult rat femoral trabecular bone. Calcif Tissue Int 50: 93-95, 1992.
12. Kember NF. Growth hormone and cartilage cell division in hypophysectomized rats. Cell Tissue Kinet 4: 193-199, 1971.
13. Lu X, Shi Z, and Murphy LJ. Growth hormone suppression of insulin-like growth factor binding protein-1 promoter activity. Mol Cell Endocrinol 149: 18-19, 1999.
14. Lynch MP, Stein JL, Stein GS, and Lian JB. The influence of type I collagen on the development and maintenance of the osteoblast phenotype in primary and passaged rat calvarial osteoblasts: modification of expression of genes supporting cell growth, adhesion, and extracellular matrix mineralization. Exp Cell Res 216: 35-45, 1995.
15. Maniatopoulos C, Sodek J, and Melcher AH. Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats. Cell Tissue Res 254: 317-330, 1988.
16. Norrelund H, Fisker S, Vahi N, Borglum J, Richelsen B, Christiansen JS, and Jorgensen JOL. Evidence supporting a direct suppressive effect of growth hormone on serum IGFBP-1 levels. Experimental studies in normal, obese and GH-deficient adults. Growth Horm IGF Res 9: 52-60, 1999.
17. Onyia JE, Miller B, Hulman J, Liang J, Galvin R, Frolik C, Chandrasekhar S, Harvey AK, Bidwell J, Herring J, and Hock JM. Proliferating cells in the primary spongiosa express osteoblastic phenotype in vitro. Bone 20: 93-100, 1997.
18. Owen M. Marrow stromal cells. J Cell Sci Suppl 10: 63-76, 1988.
19. Reddi AH and Sullivan NE. Matrix-induced endochondral bone differentiation: influence of hypophysectomy, growth hormone, and thyroid stimulating hormone. Endocrinology 107: 1291-1299, 1980.
20. 2 on bone: induction of a transition from nonadherent to adherent osteoblast precursors. J Bone Miner Res 10: 474-487, 1995.
21. Sodek J, Kim RH, Ogata Y, Li J, Yamauchi M, Zang Q, and Freedman LP. Regulation of bone sialoprotein gene transcription by steroid hormones. Connect Tissue Res 32: 209-217, 1995.
22. Stein GS and Lian JB. Molecular mechanisms mediating proliferation/differentiation interrelationships during progressive development of the osteoblast phenotype. Endocr Rev 14: 424-442, 1993.
23. Stein GS and Lian J. Molecular mechanisms mediating developmental and hormone-regulated expression of genes in osteoblasts: an integrated relationship of cell growth and differentiation. In: Cellular and Molecular Biology of Bone, edited by M. Noda. San Diego, CA: Academic, 1993, p. 47-95.
24. Stein GS, Lian JB, Stein JL, Van Wijnen AJ, and Montecino M. Transcriptional control of osteoblast growth and differentiation. Physiol Rev 76: 593-629, 1996.
25. Stringa E, Filanti C, Giunciuglio D, Albini A, and Manduca P. Osteoblastic cells from rat long bone. I Characterization of their differentiation in culture. Bone 16: 663-670, 1995.
26. Syftestad GT and Urist MR. Growth-hormone dependent matrix-induced heterotropic bone formation. Proc Soc Exp Biol Med 163: 411-415, 1980.
27. Thorngren KG, Hanssson LI, Menander-Sellman K, and Stenstrom A. Effect of hypophysectomy on longitudinal bone growth in the rat. Calcif Tissue Res 11: 281-300, 1973.
28. Yao KL, Todescan R, and Sodek J. Temporal changes in matrix protein synthesis and mRNA expression during mineralized tissue formation by adult rat bone marrow cells in culture. J Bone Miner Res 9: 231-240, 1994.
29. Yeh JK, Chen M-M, and Aloia JF. Skeletal alterations in hypophysectomized rats. I. A histomorphometric study on tibial cancellous bone. Anat Rec 241: 505-512, 1995.
30. Yeh JK, Evans JF, Chen M-M, and Aloia JF. Effect of hypophysectomy on the proliferation and differentiation of rat bone marrow stromal cells. Am J Physiol Endocrinol Metab 276: E34-E42, 1999.