Gamma-hydroxybutyric acid and alcohol-related syndromes

Alcohol

Volumn 20, Issue 3, 2000, Pages 285-291

  Moncini, M ^a   Masini, E ^a   Gambassi, F ^a   Mannaioni, P F ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Alcohol withdrawal syndrome; Craving; Gamma hydroxybutyrate; Gamma hydroxybutyric acid; Gamma hydroxybutyric acid diversion

Indexed keywords

4 HYDROXYBUTYRIC ACID; ALCOHOL;

ADULT; AGED; ALCOHOL CONSUMPTION; ALCOHOL WITHDRAWAL; ALCOHOLISM; CLINICAL FEATURE; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DETOXIFICATION; DOSE TIME EFFECT RELATION; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; FEMALE; GASTROINTESTINAL SYMPTOM; HUMAN; MAJOR CLINICAL STUDY; MALE; RELAPSE; RISK BENEFIT ANALYSIS; VERTIGO; VOMITING;

ADOLESCENT; ADULT; AGED; ALCOHOL WITHDRAWAL DELIRIUM; ALCOHOL-RELATED DISORDERS; ALCOHOLISM; DOUBLE-BLIND METHOD; FEMALE; HUMANS; HYDROXYBUTYRATES; MALE; MIDDLE AGED; PLACEBOS; RECURRENCE;

EID: 0034043188     PISSN: 07418329     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0741-8329(99)00093-2     Document Type: Article

References (30)

1. Addolorato G., Cibin M., Capristo E., Beghè F., Gessa G.L., Stefanini F.G., Gasbarrini G. Maintaining abstinence for alcohol with γ-hydroxybutyric acid. Lancet. 951:1988;38.
2. Addolorato G., Castelli E., Stefanini G.F., Casella G., Caputo F., Marsigli L., Bernardi M., Gasbarrini G. An open multicentric study evaluating 4-hydroxybutyric acid sodium salt in the medium term treatment of 179 alcohol dependent subjects. Alcohol Alcohol. 31:1996;341-345.
3. +-dependent uptake system for gamma-hydroxybutyrate in membrane vesicles prepared from rat brain. J Neurochem. 38:1982;1570-1575.
4. B receptors J Neural Transm Supp. 35:1992;155-177.
5. Bessman S.P., Fishbein B.J. Gamma-hydroxybutyrate, a normal brain metabolite. Nature. 200:1963;1207-1208.
6. Canton, G., Ferri, M., Forza, G., Brambilla, C., Minazzato, L., & Gallimberti, L. (1991). Un questionario per la valutazione del craving alcolico: l'ACS (Alcohol Craving Scale). I Congresso Nazionale SITD Roma.
7. Carter J., Mofenson H., Caraccio T. Gamma-hydroxybutyrate use. New York and Texas, 1995-1996 Morb Mortal Wkly Rep. 46:1997;281-283.
8. Di Bello M.G., Gambassi F., Mugnai L., Masini E., Mannaioni P.F. Gamma-hydroxybutyric acid induced suppression and prevention of alcohol withdrawal syndrome and relief of craving in alcohol-dependent patients. Alcologia. 7:1995;111-118.
9. Fadda F., Argiolas A., Melis M.R., De Montis G., Gessa G.L. Suppression of voluntary ethanol consumption in rats by gamma-butyrolactone. Life Sci. 32:1983;1471-1477.
10. Fadda F., Colombo G., Mosca E., Gessa G.L. Suppression by gamma-hydroxybutyric acid of ethanol withdrawal syndrome in rats. Alcohol Alcohol. 24:1989;447-451.
11. Ferrara S.D., Tedeschi L., Frison G., Rossi A. Fatality due to gamma-hydroxybutyric acid (GHB) and heroin intoxication. J Forensic Sci. 40:1995;501-504.
12. Friedman J., Westlake R., Furman R. Grievous bodily harm. gamma-hydroxybutyrate abuse leading to a Werniche-Korsakoff syndrome Neurology. 46:1996;469-471.
13. Gallimberti L., Canton G., Gentile N., Ferri M., Cibin M., Ferrara S.D., Fadda F., Gessa G.L. Gamma-hydroxybutyric acid for the treatment of alcohol withdrawal syndrome. Lancet. 2:1989;787-789.
14. Gallimberti L., Ferrara S.D., Gessa G.L. Il GHB nel trattamento della dipendenza alcolica. Monograph Series 4. 1992;Addiction Res Foundation Italy, Padova. a.
15. Gallimberti L., Ferri M., Ferrara S.D., Fadda F., Gessa G.L. Gamma-hydroxybutyric acid in the treatment of alcohol dependence. a double blind study Alcohol Clin Exp Res. 16:1992;673-676. b.
16. Gallimberti L., Cibin M., Pagnin P., Sabbion R., Pani P.P., Pirastu R., Ferrara S.D., Gessa G.L. Gamma-hydroxybutyric acid for treatment of opiate withdrawal syndrome. Neuropsychopharmacol. 9:1993;77-81.
17. Gallimberti L., Schifano F., Forza G., Miconi L., Ferrara S.D. Clinical efficacy of gamma-hydroxybutyric acid in treatment of opiate withdrawal. Eur Arch Psychiatry Clin Neurosci. 244:1994;113-114.
18. Galloway G.P., Frederick S.L., Staggers F.E. Physical dependence on sodium oxybate. Lancet. 343:1994;57.
19. Galloway G.P., Frederick S.L., Staggers F.E., Gonzales M., Stalcup S.A., Smith D.E. Gamma-hydroxybutyrate. an emerging drug of abuse that causes physical dependence Addiction. 92:1997;89-96.
20. Gessa G.L., Diana M., Fadda F., Colombo G. Gamma-hydroxybutyric acid (GHB) for the treatment of alcohol dependence. Eur Neuropsychopharmacol. 3:1993;224-225.
21. Gessa G.L., Agabio R., Lobina C., Pani M.L., Reali R., Colombo G. Mechanism of the antialcohol effect of gamma-hydroxybutyric acid. Alcohol. 20:2000;271-276.
22. Howard S.G., Feigenbaum J.J. Effect of γ-hydroxybutyrate on central dopamine release in vivo. Biochem Pharmacol. 53:1997;103-110.
23. Laborit G., Larcan A., Kind A. Le gamma-hydroxybutyrate en anesthesie neuro-chirurgicale. Neurochirurgie. 8:1962;104-107.
24. Louagie H.K., Verstraete A.G., De Soete C.J., Baetens D.G., Calle P.A. A sudden awakening from a near coma after combined intake of gamma-hydroxybutyric acid (GHB) and ethanol. J Toxicol Clin Toxicol. 35:1997;591-594.
25. Mamelak M., Scharr M.B., Woods M. Treatment of narcolepsy and sleep apnea with gamma-hydroxybutyrate. a review of clinical and sleep laboratory findings Sleep. 9:1986;285-289.
26. B receptor agonist. Eur J Pharmacol. 321:1997;67-75.
27. Takahara J., Yunoki S., Yakushiji W., Yamauchi W., Yamane J. Stimulatory effect of gamma-hydroxybutyric acid on growth hormone and prolactin release in humans. J Clin Endocrinol Metab. 44:1977;1014-1017.
28. Tunnicliff G. Sites of action of gamma-hydroxybutyrate (GHB). a neuroactive drug with abuse potential J Toxicol Clin Toxicol. 35:1997;581-590.
29. Van Cauter E., Plat L., Scharf M.B., Leproult R., Cespedes S., L'Hermite-Baleriaux M., Copinschi G. Simultaneous stimulation of slow-wave sleep and growth hormone secretion by gamma-hydroxybutyrate in normal young man. J Clin Invest. 100:1997;745-753.
30. Walter, H., Benda, N., Grunhut, C., Nimmerrichter, A., Mader, R., & Lesch, O. M. (in press). GHB efficacy in the treatment of alcohol withdrawal. Alcohol.