Molecular evidences for a role of HSV-1 in multiple sclerosis clinical acute attack

Journal of NeuroVirology

Volumn 6, Issue SUPPL. 2, 2000, Pages

  Ferrante, Pasquale ^a,b   Mancuso, Roberta ^b   Pagani, Elisabetta ^b   Guerini, Franca Rosa ^b   Calvo, Maria Gaetana ^b   Saresella, Marina ^b   Speciale, Livianna ^b   Caputo, Domenico ^b  

^a UNIVERSITY OF MILAN   (Italy)

^b IRCCS FONDAZIONE DON CARLO GNOCCHI   (Italy)

Author keywords

Clinical relapse; DNA; Herpes simplex type 1 and 2; Herpesviruses; Messenger RNA; Multiple sclerosis

Indexed keywords

VIRUS DNA;

ADULT; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; EPSTEIN BARR VIRUS; FEMALE; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CYTOMEGALOVIRUS; HUMAN HERPESVIRUS 6; MALE; MONONUCLEAR CELL; MULTIPLE SCLEROSIS; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL; RELAPSE; VIRUS REACTIVATION;

ACUTE DISEASE; ADULT; DNA, VIRAL; FEMALE; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HERPESVIRUS 2, HUMAN; HUMANS; LEUKOCYTES, MONONUCLEAR; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS, RELAPSING-REMITTING; RNA, MESSENGER; RNA, VIRAL; SEROEPIDEMIOLOGIC STUDIES;

DNA VIRUSES; HERPES; HERPES VIRUS 6; HERPESVIRIDAE; HUMAN HERPES VIRUS; HUMAN HERPES VIRUS 6; HUMAN HERPESVIRUS 1; HUMAN HERPESVIRUS 4; HUMAN HERPESVIRUS 5; HUMAN HERPESVIRUS 6;

EID: 0034040702     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (32)

1. Andersen O, Lygner PE, Bergström T, Andersson M, Vahlne A (1993). Viral infections trigger multiple sclerosis relapses: a prospective seroepidemiological study. J Neurol 240: 417-422.
2. Bergstrom T (1999). Herpesviruses: a rationale for antiviral treatment in multiple sclerosis. Antiviral Res 41: 1-19.
3. Bergstrom T, Anderson O, Vahlne A (1989). Isolation of herpes simplex virus type 1 during first attack of multiple sclerosis. Ann Neurol 26: 283.
4. Bray PF, Culp KW (1992). Demyelinating disease after neurollogically complicated primary Epstein-Barr virus infection. Neurology 42: 278-282.
5. Bray PF, Luka J (1992). Antibodies against Epstein-Barr nuclear antigen (EBNA) in multiple sclerosis CSF and two pentapeptide sequence identities between EBNA and myelin basic protein. Neurology 42: 1798-1804.
6. Colombo E, Magistrelli C, Mendozzi E, Cattaneo E, Achilli G, Ferrante P (1995). HTLV infection among italian intravenous drug users and north african subjects detected by the polymerase chain reaction and serological methods. J Med Virol 47: 10-15.
7. Dalgleish AG (1997). Viruses and multiple sclerosis. Acta Neurol Scand S169: 8-15.
8. Ferrante P, Mancuso R (1996). Viral cerebrospinal fluid virological analysis in mulitpile sclerosis. In: Cerebrospinal fluid analysis in multiple sclerosis. Thompson EJ, Troiano M, Livrea P, (eds). Springer-Verlag Italia: Milano Italy, pp 1-14.
9. Ferrante P, Omodeo-Zorini E, Zuffolato MR, Mancuso R, Caldarelli-Stefano R, Puricelli, Mediati M, Losciale L, Caputo D (1997). Human T-cell lymphotropic virus fax and Epstein-Barr virus DNA in peripheral blood of multiple sclerosis patients during acute attack. Acta Neurol Scand S169: 79-85.
10. Gran B, Hemmer B, Vergelli M, McFarland, Martin R (1999). Molecular mimicry and multiple sclerosis: degenerate T-cell recognition and the induction of autoimmunity. Ann Neurol 45: 559-567.
11. Haahr S, Sommerlund M, Møller-Larsen A, Mogensen S, Andersen HMK (1992). Is multiple sclerosis caused by a dual infection with retrovirus and Epstein-Barr virus? Neuroepidemiology 11: 299-303.
12. Haahr S, Koch-Henriksen N, Møller-Larsen A, Eriksen LS, Andersen HMK (1995). Increased risk of multiple sclerosis after late Epstein-Barr virus infection: a historical prospective study. Multiple Sclerosis 1: 73-77.
13. Huang LM, Lee CY, Lee PI, Chen JM, Wang PJ (1991). Meningitis caused by human herpesvirus-6. Arch Dis Child 66: 1443-1444.
14. Ishiguro N, Yamada S, Takahashi T, Takahashi Y, Togashi T, Okuno T, Yamanishi K (1990) Meningoencephalitis associated with HHV-6 related exanthem subitum. Acta Pediatr Scand 79: 987-989.
15. Kirk J, Zhou AL (1996). Viral infection at the blood-brain barrier in multiple sclerosis: an ultrastructural study of tissues from a UK Regional Brain Bank. Multiple Sclerosis 1: 242-252.
16. Kurtzke JF (1993). Epidemiologic evidence for multiple sclerosis as an infection. Clin Microbiol Rev 6: 382-427.
17. Lindeberg C, Andersen O, Vahlne A, Dalton M, Runmarker B (1991). Epidemiological investigation of the association between infectious mononucleosis and multiple sclerosis. Neuroepidemiology 10: 62-65.
18. Lycke J, Svennerholm B, Hjelmquist E, Frisen L, Badr G, Andersson M, Vahlne A, Andersen O (1996). Acyclovir treatment of relapsing-remitting multiple sclerosis. J Neurol 243: 214-224.
19. Martin JR (1981). Herpes simplex virus type 1 and 2 and multiple sclerosis. Lancet 2: 777-781.
20. McGeoch DJ, Dalrymple MA, Davison AJ, Dolan A, Frame MC, McNab D, Perry LJ, Scott JE, Taylor P (1988). The complete DNA sequence of the long unique region in the genome of Herpes Simplex Virus type 1. J Gen Virol 69: 1531-1574.
21. Monteyne P, Bureau JF, Brahic M (1998). Viruses and multiple sclerosis. Curr Opin Neurol 4: 287-291.
22. Munch M, Riisom K, Christensen T, Moller-Larsen A, Haahr S (1998). The significance of Epstein-Barr virus seropositivity in multiple sclerosis patients? Acta Neurol Scand 97: 171-174.
23. Panitch HS (1994). Influence of infection on exacerbations of multiple sclerosis. Ann Neurol 36: S25-S28.
24. Perron H, Garson JA, Bedin F, Beseme F, Paranhos-Baccala G, Komuria-Pradel F, Mallet F, Tuke PW, Voisset C, Blond JL, Lalande B, Seigneurin JM, Mandrand B and The Collaborative Research Group on Multiple Sclerosis (1997). Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis. Proc Natl Acad Sci USA 94: 7583-7588.
25. Poser CM (1993). The pathogenesis of multiple sclerosis. J Neurol Sci 115: S3-S15.
26. Poser CM, Paty DW, Scheinberg L, McDonald WI, Davis FA, Ebers GC, Johnson KP, Sibley WA, Silberg DH, Tourtellotte WW (1983). New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 13: 227-231.
27. Ross RT, Cheang M, Landry G, Klassen L, Doerksen K (1999). Herpes zoster and multiple sclerosis. Can J Neurol Sci 26: 29-32.
28. Sanders VJ, Felisan S, Waddel A, Tourtellotte WW (1996). Detection of herpesviridae in postmortem multiple sclerosis brain tissue and controls by polimerase chain reaction. J Neurovirol 2: 249-258.
29. Secchiero P, Carrigan DR, Asano Y, Benedetti L, Crowley RW, Komaroffet AL, Gallo RC, Lusso P (1995). Detection of human herpesvirus 6 in plasma of children with primary infection and immunosuppressed patients by polymerase chain reaction. J Inf Dis 171: 273-280.
30. Sibley WA, Bamford CR, Clark K (1985). Clinical viral infections and multiple sclerosis. Lancet, 1: 1313-1315.
31. Soldan SS, Berti R, Salem N, Secchiero P, Flamand L, Calabresi PA, Brennan MB, Maloni HW, McFarland HF, Lin HC, Patnaik M, Jacobson S (1997). Association of human herpesvirus type 6 with multiple sclerosis: increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA. Nature Med 3: 1394-1397.
32. Whitley RJ (1996). Herpes simplex viruses. In: Virology. Vol. 2 Fields BN, Knipe DM, Howley PM, Chanock RM, Melnick JL, Monath TP, Roizman B, Straus SE (eds). Lippincott-Raven Publisher: Philadelphia, pp 2297-2342.