Function of pancreatic islets isolated from a type 1 diabetic patient [3]

Diabetes Care

Volumn 23, Issue 5, 2000, Pages 701-703

  Marchetti, Piero ^a,d   Dotta, Francesco ^b   Ling, Zhidong ^c   Lupi, Roberto ^a   Del Guerra, Silvia ^a   Santangelo, Carmela ^b   Realacci, Massimo ^b   Marselli, Lorella ^a   Di Mario, Umberto ^b   Navalesi, Renzo ^a  

^a UNIVERSITY OF PISA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^d CISANELLO HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCAGON RELEASE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; LANGERHANS CELL; LETTER; PANCREAS ISLET BETA CELL;

EID: 0034038911     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.23.5.701     Document Type: Letter

References (7)

1. Conget I, Fernadez-Alvarez J, Ferrer J, Sarn Y, Novials A, Somoza N, Pujol-Borrel R, Casamitjana R, Gomis R: Human pancreatic islet function at the onset of type 1 (insulin-dependent) diabetes mellitus. Diabetologia 36:358-360, 1993
2. Marchetti P, Giannarelli R, Cosimi S, Masiello P, Coppelli A, Viacava P, Navalesi R: Massive isolation, morphological and functional characterization, and xeno-transplantation of bovine pancreatic islets. Diabetes 44:375-381, 1995
3. Keymeulen B, Ling Z, Gorus FK, Delvaux G, Bouwens L, Grupping A, Hendrieckx C, Pipeleers-Marichal M, Van Schravendijk C, Salmela K, Pipeleers DG: Implantation of standardized beta-cell graft in a liver segment of IDDM patients: graft and recipient characteristics in two cases of insulin-independence under maintainance immunosuppression for prior kidney graft. Diabetologia 41:452-459, 1998
4. Pupilli C, Giannini S, Marchetti P, Lupi R, Antonelli A, Malavasi F, Takasawa S, Okamoto H, Ferrannini E: Autoantibodies to CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) in Caucasian patients with diabetes: effects on insulin release from human islet cells. Diabetes 48:2309-2315, 1999
5. Ling Z, Pipeleers D: Prolonged exposure of human beta-cells to elevated glucose levels results in sustained cellular activation with a loss of glucose regulation. J Clin Invest 98:2805-2812, 1996
6. Strandell E, Eizirik DL, Sandler S: Reversal of beta-cell suppression in vitro in pancreatic islets isolated from NOD mice during the phase preceding insulin-dependent diabetes mellitus. J Clin Invest 85:1944-1950, 1990
7. Ishida K, Mizuno A, Sano T, Shi K, Shima K: Plasma glucagon responses to insulin-induced hypolgycemia and arginine in spontaneous non-insulin-dependent diabetes mellitus rats. Otsuka Long Evans Tokushima Fatty (OLEFT) strain. Acta Endocrinol (Copenh) 129:585-593, 1993