Control of fever by continuous, low-dose diclofenac sodium infusion in acute cerebral damage patients

Intensive Care Medicine

Volumn 26, Issue 5, 2000, Pages 552-557

  Cormio, M ^a   Citerio, G ^a   Spear, S ^a   Fumagalli, R ^a   Pesenti, A ^a  

^a SAN GERARDO HOSPITAL   (Italy)

Author keywords

Cerebral perfusion pressure; Diclofenac sodium; Fever; Head trauma; Intracranial pressure; Subarachnoid haemorrhage

Indexed keywords

DICLOFENAC;

AGED; ARTICLE; BRAIN FUNCTION; BRAIN INJURY; CLINICAL ARTICLE; FEMALE; FEVER; HEMODYNAMIC PARAMETERS; HUMAN; INTRACRANIAL PRESSURE; KIDNEY FUNCTION; LIVER FUNCTION; MALE; PERFUSION PRESSURE; SUBARACHNOID HEMORRHAGE;

ACUTE DISEASE; ADULT; ANALYSIS OF VARIANCE; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CRANIOCEREBRAL TRAUMA; DICLOFENAC; FEMALE; FEVER; HEMODYNAMIC PROCESSES; HUMANS; INFUSIONS, INTRAVENOUS; INTENSIVE CARE UNITS; INTRACRANIAL PRESSURE; KIDNEY FUNCTION TESTS; LIVER FUNCTION TESTS; MALE; RETROSPECTIVE STUDIES; SUBARACHNOID HEMORRHAGE;

EID: 0034038375     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001340051203     Document Type: Article

References (20)

1. 1. Albrecht RF, Wass CT, Lanier WL (1998) Occurrence of potentially detrimental temperature alterations in hospitalized patients at risk of brain injury. Mayo Clin Proc 73: 629-635
2. 2. Minamisawa H, Smith ML, Siesjo BK (1990) The effect of mild hyperthermia and hypothermia on brain damage following 5, 10, and 15 m of forebrain ischemia. Ann Neurol 28: 26-33
3. 3. Coimbra C, Boris-Moller F, Drake M, Wieloch T (1996) Diminished neuronal damage in the rat brain by late treatment with the antipyretic drug dipyrone or cooling following cerebral ischemia. Acta Neuropathol (Berl) 92: 447-53
4. 4. Dietrich WD, Busto R, Valdes I, Loor Y (1990) Effects of normothermic versus mild hyperthermic forebrain ischemia in rats. Stroke 21: 1318-1325
5. 5. Kim Y, Busto R, Dietrich WD, Kraydieh S, Ginsberg MD (1996) Delayed postischemic hyperthermia in awake rats worsens the histopathological outcome of transient focal cerebral ischemia. Stroke 27: 2274-80
6. 6. Sharma HS, Westman J, Nyberg F (1998) Pathophysiology of brain edema and cell changes following hyperthermic brain injury. Prog Brain Res 115: 351-412
7. 7. Gasen RA, Pandolfi S, Laing I, Casey D (1974) Experimental study of relation of fever to cerebral edema. J Neurosurg 41: 576-581
8. 8. Takagi K, Ginsberg MD, Globus MY, Martinez E, Busto R (1994) Effect of hyperthermia on glutamate release in ischemic penumbra after middle cerebral artery occlusion in rats. Am J Physiol 267: H1770-6
9. 9. Wass CT, Lanier WL, Hofer RE, et al (1995) Temperature changes of > or = 1 degree C alter functional neurologic outcome and histopathology in a canine model of complete cerebral ischemia. Anesthesiology 83: 325-35
10. 10. Jones PA, Andrews PJ, Midgley S, et al (1994) Measuring the burden of secondary insults in head-injured patients during intensive care. J Neurosurg Anesth 6:4-14
11. 11. Ginsberg MD, Busto R (1998) Combating hyperthermia in acute stroke: a significant clinical concern. Stroke 29: 529-34
12. 12. Zandstra DF, Stoutenbeek CP, Alexander JP (1983) Antipyretic therapy with diclofenac sodium. Observations on effects and serious effects in critically ill patients. Intensive Care Med 9: 21-23
13. 13. Rossi S, Colombo A, Calvi MR, et al (1998) Pyrexia in head injury: results of a multicentric study. Intensive Care Med (Suppl) 24: S61
14. 14. Pesenti A, Riboni A, Basilico E, et al (1986) Antipyretic therapy in ICU patients: evaluation of low dose diclofenac sodium. Intensive Care Med 12: 370-73
15. 15. Kluger MJ, Ringler DH, Anver MR (1975) Fever and survival. Science 188: 166-8
16. 16. Kluger MJ (1986) Is fever beneficial? Yale J Biol Med 59: 89-95
17. 17. Roberts NJ (1979) Temperature and host defence. Microbiol Rev 43: 241-59
18. 18. Fischler MR Reinhart WH (1997) Fever: friend or enemy? Schweiz Med Wochenschr 127: 864-70
19. 19. Villar J, Blazquez M, Manzano JL, Slutsky A (1991) Hypothermia decreases mortality in human septic adult respiratory distress syndrome (ARDS). Crit Care Med (Suppl) 19: S90
20. 20. Styrt B, Sugarman B (1990) Antipyresis and fever. Arch Intern Med 150: 1589-1597