Characterization of the murine BSE infectious agent

Journal of General Virology

Volumn 81, Issue 6, 2000, Pages 1615-1620

  Manousis, T ^a   Verghese Nikolakaki, S ^a   Keyes, P ^b   Sachsamanoglou, M ^a   Dawson, M ^b   Papadopoulos, O ^a   Sklaviadis, Theodoros K ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b VETERINARY LABORATORIES AGENCY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GUANIDINE; HYDROCHLORIC ACID; NUCLEIC ACID; PRION PROTEIN;

ANIMAL TISSUE; ARTICLE; BOVINE SPONGIFORM ENCEPHALOPATHY; CONTROLLED STUDY; ENZYME CONFORMATION; ENZYME DENATURATION; MOUSE; NONHUMAN; PRION; PRIORITY JOURNAL; SOLUBILIZATION; SUCROSE DENSITY GRADIENT CENTRIFUGATION; VIRUS INFECTIVITY; VIRUS PARTICLE;

ANIMALIA; BOVINAE; MURINAE;

EID: 0034035758     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-81-6-1615     Document Type: Article

References (26)

1. Akowitz, A., Sklaviadis, T. & Manuelidis, L. (1994). Endogenous viral complexes with long RNA cosediment with the agent of Creutzfeldt-Jakob disease. Nucleic Acids Research 22, 1101-1107.
2. Alper, T., Haig, D. A. & Clarke, M. C. (1966). The exceptionally small size of the scrapie agent. Biochemical and Biophysical Research Communications 22, 278-284.
3. Brown, P., Liberski, P.P., Wolff, A. & Gajdusek, D. C. (1990). Conservation of infectivity in purified fibrillary extracts of scrapie-infected hamster brain after sequential enzymatic digestion or polyacrylamide gel electrophoresis. Proceedings of the National Academy of Sciences, USA 87, 7240-7244.
4. Bruce, M., Chree, A., McConnell, I., Foster, J., Pearson, G. & Fraser, H. (1994). Transmission of bovine spongiform encephalopathy and scrapie to mice: strain variation and the species barrier. Philosophical Transactions of the Royal Society of London Series B 343, 405-411.
5. Sc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene. Molecular Medicine 1, 19-30.
6. Caughey, B., Raymond, G. J., Kocisko, D. A. & Lansbury, P. T., Jr (1997). Scrapie infectivity correlates with converting activity, protease resistance, and aggregation of scrapie-associated prion protein in guanidine denaturation studies. Journal of Virology 71, 4107-4110.
7. Gasset, M., Baldwin, M. A., Fletterick, R. J. & Prusiner, S. B. (1993). Perturbation of the secondary structure of the scrapie prion protein under conditions that alter infectivity. Proceedings of the National Academy of Sciences, USA 90, 1-5.
8. Hill, A. F., Antoniou, M. & Collinge, J. (1999). Protease-resistant prion protein produced in vitro lacks detectable infectivity. Journal of General Virology 80, 11-14.
9. Kaneko, K., Peretz, D., Pan, K. M., Blochberger, T. C., Wille, H., Gabizon, R., Griffith, O. H., Cohen, F. E., Baldwin, M. A. & Prusiner, S. B. (1995). Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform. Proceedings of the National Academy of Sciences, USA 92, 11160-11164.
10. Kascsak, R. J., Fersko, R., Pulgiano, D., Rubenstein, R. & Carp, R. I. (1997). Immunodiagnosis of prion disease. Immunological Investigations 26, 259-268.
11. Kellings, K., Meyer, N., Mirenda, C., Prusiner, S. B. & Riesner, D. (1992). Further analysis of nucleic acids in purified scrapie prion preparations by improved return refocusing gel electrophoresis. Journal of General Virology 73, 1025-1029.
12. Kocisko, D. A., Come, J. H., Priola, S. A., Chesebro, B., Raymond, G. J., Lansbury, P. T. & Caughey, B. (1994). Cell-free formation of protease-resistant prion protein. Nature 370, 471-474.
13. Kocisko, D. A., Lansbury, P. T., Jr & Caughey, B. (1996). Partial unfolding and refolding of scrapie-associated prion protein: evidence for a critical 16-kDa C-terminal domain. Biochemistry 35, 13434-13442.
14. Lasmezas, C. I., Deslys, J. P., Robain, O., Jaegly, A., Beringue, V., Peyrin, J. M., Fournier, J. G., Hauw, J. J., Rossier, J. & Dormont, D. (1997). Transmission of the BSE agent to mice in the absence of detectable abnormal prion protein. Science 275, 402-405.
15. Manuelidis, L., Sklaviadis, T., Akowitz, A. & Fritch, W. (1995). Viral particles are required for infection in neurodegenerative Creutzfeldt-Jakob disease. Proceedings of the National Academy of Sciences, USA 92, 5124-5128.
16. Millson, G. C. & Manning, E. J. (1979). The effect of selected detergents on scrapie infectivity. In Slow Transmissible Diseases of the Nervous System, vol. 2, pp. 409-424. Edited by S. B. Prusiner & W. J. Hadlow. New York: Academic Press.
17. Prusiner, S. B. (1982). Novel proteinaceous infectious particles cause scrapie. Science 216, 136-144.
18. Prusiner, S. B., Groth, D. F., Cochran, S. P., Masiarz, F. R., McKinley, M. P. & Martinez, H. M. (1980). Molecular properties, partial purification, and assay by incubation period measurements of the hamster scrapie agent. Biochemistry 19, 4883-4891.
19. Prusiner, S. B., Bolton, D. C., Groth, D. F., Bowman, K. A., Cochran, S. P. & McKinley, M. P. (1982). Further purification and characterization of scrapie prions. Biochemistry 21, 6942-6950.
20. Prusiner, S. B., Groth, D., Serban, A., Stahl, N. & Gabizon, R. (1993). Attempts to restore scrapie prion infectivity after exposure to protein denaturants. Proceedings of the National Academy of Sciences, USA 90, 2793-2797.
21. Riesner, D., Kellings, K., Post, K., Wille, H., Serban, H., Groth, D., Baldwin, M. A. & Prusiner, S. B. (1996). Disruption of prion rods generates 10-nm spherical particles having high α-helical content and lacking scrapie infectivity. Journal of Virology 70, 1714-1722.
22. Safar, J., Roller, P. P., Gajdusek, D. C. & Gibbs, C. J., Jr (1993). Conformational transitions, dissociation, and unfolding of scrapie amyloid (prion) protein. Journal of Biological Chemistry 268, 20276-20284.
23. Sklaviadis, T. K., Manuelidis, L. & Manuelidis, E. E. (1989). Physical properties of the Creutzfeldt-Jakob disease agent. Journal of Virology 63, 1212-1222.
24. Sklaviadis, T., Akowitz, A., Manuelidis, E. E. & Manuelidis, L. (1990). Nuclease treatment results in high specific purification of Creutzfeldt-Jacob disease infectivity with a density characteristic of nucleic acid-protein complexes. Archives of Virology 112, 215-228.
25. Somerville, R. A. & Dunn, A. J. (1996). The association between PrP and infectivity in scrapie and BSE infected mouse brain. Archives of Virology 141, 275-289.
26. Weiss, S., Proske, D., Neumann, M., Groschup, M. H., Kretzschmar, H. A., Famulok, M. & Winnacker, E. L (1997). RNA aptamers specifically interact with the prion protein PrP. Journal of Virology 71, 8790-8797.